E-R control efficiency

high-resolution terminology - matching measurements at high-resolution

E-R control efficiency

Description

The apparent excess ETS capacity factor over R (E-R coupling control factor), j_ExR = (E-R)/E = 1-R/E, is an expression of the relative scope of increasing ROUTINE respiration in intact cells by uncoupling. j_ExR = 0.0 for zero excess capacity when R=E; j_ExR = 1.0 for the maximum limit when R=0. The ROUTINE state of intact cells is stimulated to ETS by uncoupler titration. Since ETS capacity is significantly higher than OXPHOS capacity in various cell types (as shown by cell ergometry), E-R or j_ExR is not a reseve capacity available for the cell to increase oxidative phosphorylation, but strictly a scope (reserve?) for uncoupling respiration.

Abbreviation: j_ExR

Reference: Flux control factor

MitoPedia methods: Respirometry 

MitoPedia topics: "Respiratory control ratio" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property. Respiratory control ratio"Respiratory control ratio" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property. 

Compare

• Excess E-P capacity factor
• More details: ETS coupling efficiency