Difference between revisions of "E-L net ET capacity"
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{{MitoPedia | {{MitoPedia | ||
|abbr=''≈E'' | |abbr=''≈E'' | ||
|description=[[ | |description=[[Image:E-L.jpg|50 px|link=Free ETS capacity|Free ETS capacity]] | ||
The '''free ETS capacity''', ''≈E'', is the [[ETS capacity]] corrected for [[LEAK respiration]], ''≈E'' = ''E-L''. ''≈E'' is the respiratory capacity potentially available for ion transport and phosphorylation of ADP to ATP. Oxygen consumption in the ETS state, therefore, is partitioned into the free ETS capacity, ''≈E'', and resting LEAK respiration, ''L<sub>P</sub>'', compensating for proton leaks, slip and cation cycling: ''E'' = ''≈E''+''L<sub>P</sub>'' (see [[free OXPHOS capacity]]). | The '''free ETS capacity''', ''≈E'', is the [[ETS capacity]] corrected for [[LEAK respiration]], ''≈E'' = ''E-L''. ''≈E'' is the respiratory capacity potentially available for ion transport and phosphorylation of ADP to ATP. Oxygen consumption in the ETS state, therefore, is partitioned into the free ETS capacity, ''≈E'', and resting LEAK respiration, ''L<sub>P</sub>'', compensating for proton leaks, slip and cation cycling: ''E'' = ''≈E''+''L<sub>P</sub>'' (see [[free OXPHOS capacity]]). | ||
|info=[[Gnaiger 2014 MitoPathways]] | |info=[[Gnaiger 2014 MitoPathways]] | ||
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|mitopedia topic=Respiratory state | |mitopedia topic=Respiratory state | ||
}} | }} | ||
[[File:EPL-free and excess.jpg|right|300px|thumb|[[Gnaiger 2014 MitoPathways |The Blue Book 2014]]: Fig. 2.4.]] | |||
== Compare == | == Compare == | ||
* [[Free OXPHOS capacity]] | * [[Free OXPHOS capacity]] | ||
Revision as of 12:31, 18 January 2015
- high-resolution terminology - matching measurements at high-resolution
E-L net ET capacity
Description
The free ETS capacity, ≈E, is the ETS capacity corrected for LEAK respiration, ≈E = E-L. ≈E is the respiratory capacity potentially available for ion transport and phosphorylation of ADP to ATP. Oxygen consumption in the ETS state, therefore, is partitioned into the free ETS capacity, ≈E, and resting LEAK respiration, LP, compensating for proton leaks, slip and cation cycling: E = ≈E+LP (see free OXPHOS capacity).
Abbreviation: ≈E
Reference: Gnaiger 2014 MitoPathways
MitoPedia methods:
Respirometry
MitoPedia topics: "Respiratory state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property.
Respiratory state"Respiratory state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property.
