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Difference between revisions of "E-L net ET capacity"

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{{MitoPedia
{{MitoPedia
|abbr=''≈E''
|abbr=''≈E''
|description=[[Image:E-L.jpg|50 px|Free ET-capacity]] The '''Free ET-capacity''', ''≈E'', is the [[ET capacity]] corrected for [[LEAK respiration]], ''≈E'' = ''E-L''. ''≈E'' is the respiratory capacity potentially available for ion transport and phosphorylation of ADP to ATP. Oxygen consumption in the ET-pathway state, therefore, is partitioned into the free ET capacity, ''≈E'', and LEAK respiration, ''L<sub>P</sub>'', compensating for proton leaks, slip and cation cycling: ''E'' = ''≈E''+''L<sub>P</sub>'' (see [[free OXPHOS capacity]]).
|description=[[Image:E-L.jpg|50 px|Free ET-capacity]] The '''Free ET-capacity''', ''≈E'', is the [[ET-capacity]] corrected for [[LEAK respiration]], ''≈E'' = ''E-L''. ''≈E'' is the respiratory capacity potentially available for ion transport and phosphorylation of ADP to ATP. Oxygen consumption in the ET-pathway state, therefore, is partitioned into the free ET-capacity, ''≈E'', and LEAK respiration, ''L<sub>P</sub>'', compensating for proton leaks, slip and cation cycling: ''E'' = ''≈E''+''L<sub>P</sub>'' (see [[free OXPHOS capacity]]).
|info=[[Gnaiger 2014 MitoPathways]]
|info=[[Gnaiger 2014 MitoPathways]]
}}
}}
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== Coupling control states for ''≈E'' ==
== Coupling control states for ''≈E'' ==
::» [[Respiratory state]]
::» [[Respiratory state]]
* [[Reference state]], ''Z<sub>X</sub>'': [[Image:E.jpg|link=ET capacity|ET capacity]] [[ET capacity]], ''E'' = ''E´''-ROX
* [[Reference state]], ''Z<sub>X</sub>'': [[Image:E.jpg|link=ET-capacity|ET-capacity]] [[ET-capacity]]; ''E'' = ''E´''-''Rox''
* [[Background state]], ''Y<sub>X</sub>'': [[Image:L.jpg|link=LEAK respiration|LEAK]] [[LEAK respiration]], ''L'' = ''L´''-ROX
* [[Background state]], ''Y<sub>X</sub>'': [[Image:L.jpg|link=LEAK respiration|LEAK]] [[LEAK respiration]]; ''L'' = ''L´''-''Rox''
* [[Metabolic control variable]], ''X=Z<sub>X</sub>-Y<sub>X</sub>'': [[Image:E-L.jpg|50 px|link=Free ET-capacity |Free ET-capacity]] Scope of uncoupler stimulation, [[Free ET-capacity]], ''≈E'' = ''E-L''
* [[Metabolic control variable]], ''X=Z<sub>X</sub>-Y<sub>X</sub>'': [[Image:E-L.jpg|50 px|link=Free ET-capacity |Free ET-capacity]] Scope of uncoupler stimulation, [[Free ET-capacity]]; ''≈E'' = ''E-L''





Revision as of 22:21, 4 January 2018


high-resolution terminology - matching measurements at high-resolution


E-L net ET capacity

Description

Free ET-capacity The Free ET-capacity, ≈E, is the ET-capacity corrected for LEAK respiration, ≈E = E-L. ≈E is the respiratory capacity potentially available for ion transport and phosphorylation of ADP to ATP. Oxygen consumption in the ET-pathway state, therefore, is partitioned into the free ET-capacity, ≈E, and LEAK respiration, LP, compensating for proton leaks, slip and cation cycling: E = ≈E+LP (see free OXPHOS capacity).

Abbreviation: ≈E

Reference: Gnaiger 2014 MitoPathways


MitoPedia concepts: Respiratory state, Recommended 


MitoPedia topics: EAGLE 

Communicated by Gnaiger E 2014-09-21, edited 2015-01-19.

Coupling control states for ≈E

» Respiratory state


Flux control factor

» Flux control factor, FCF


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