Difference between revisions of "E-L net ET capacity"
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[[File:EPL-free and excess.jpg|right|300px|thumb|[[Gnaiger 2014 MitoPathways |The Blue Book 2014]]: Fig. 2.4.]] | [[File:EPL-free and excess.jpg|right|300px|thumb|[[Gnaiger 2014 MitoPathways |The Blue Book 2014]]: Fig. 2.4.]] | ||
Revision as of 13:44, 8 February 2016
- high-resolution terminology - matching measurements at high-resolution
E-L net ET capacity
Description
The free ETS capacity, ≈E, is the ETS capacity corrected for LEAK respiration, ≈E = E-L. ≈E is the respiratory capacity potentially available for ion transport and phosphorylation of ADP to ATP. Oxygen consumption in the ETS state, therefore, is partitioned into the free ETS capacity, ≈E, and LEAK respiration, LP, compensating for proton leaks, slip and cation cycling: E = ≈E+LP (see free OXPHOS capacity).
Abbreviation: ≈E
Reference: Gnaiger 2014 MitoPathways
MitoPedia concepts:
Respiratory state
The Blue Book 2014: Fig. 2.4.
Coupling control states for ≈E
- Reference state, ZX:
ETS capacity, E = E´-ROX - Background state, YX:
LEAK respiration, L = L´-ROX - Metabolic control variable, X=ZX-YX:
Scope of uncoupler stimulation, free ETS capacity, ≈E = E-L
Flux control factor
- » Flux control factor, FCF
- Coupling control factor, 1-YX/ZX:
E-L coupling control factor, ETS coupling efficiency: j≈E = ≈E/E =(E-L)/E = 1-L/E
Compare
- mt-Preparations
Free OXPHOS capacity, ≈P = P-L - Intact cells
Free ROUTINE activity, ≈R = R-L
