Difference between revisions of "Coupled respiration"
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{{MitoPedia | {{MitoPedia | ||
|description='''Coupled respiration''' drives oxidative phosphorylation of [[ADP]] to [[ATP]] mediated by proton pumps across the inner mitochondrial membrane. [[Uncoupled respiration]], in contrast, does not lead to phosphorylation of ADP, despite of protons being pumped across the inner mt-membrane. Coupled respiration, therefore, is the coupled part of respiratory oxygen flux that pumps the fraction of protons across the inner mt-membrane which is utilized by the phosphorylation system to produce ATP from ADP and Pi. In the OXPHOS state, mitochondria are in a partially coupled state, and the corresponding coupled respiration is the [[free OXPHOS capacity]]. In the state of ROUTINE respiration, coupled respiration is the [[free ROUTINE activity]]. | |description='''Coupled respiration''' drives oxidative phosphorylation of [[ADP]] to [[ATP]] mediated by proton pumps across the inner mitochondrial membrane. [[Uncoupled respiration]], in contrast, does not lead to phosphorylation of ADP, despite of protons being pumped across the inner mt-membrane. Coupled respiration, therefore, is the coupled part of respiratory oxygen flux that pumps the fraction of protons across the inner mt-membrane which is utilized by the phosphorylation system to produce ATP from ADP and Pi. In the OXPHOS state, mitochondria are in a partially coupled state, and the corresponding coupled respiration is the [[free OXPHOS capacity]]. In the state of ROUTINE respiration, coupled respiration is the [[free ROUTINE activity]]. | ||
|info=[[Gnaiger 2014 MitoPathways]] | |info=[[Gnaiger 2014 MitoPathways]] | ||
|type=Respiration | |||
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{{MitoPedia concepts | |||
|mitopedia concept=MitoFit Quality Control System | |||
|type=Respiration | |type=Respiration | ||
}} | }} | ||
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|mitopedia method=Respirometry | |mitopedia method=Respirometry | ||
|type=Respiration | |type=Respiration | ||
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{{MitoPedia SUIT|type=Respiration | |||
}} | }} | ||
{{MitoPedia topics | {{MitoPedia topics | ||
Revision as of 23:15, 27 January 2016
- high-resolution terminology - matching measurements at high-resolution
Coupled respiration
Description
Coupled respiration drives oxidative phosphorylation of ADP to ATP mediated by proton pumps across the inner mitochondrial membrane. Uncoupled respiration, in contrast, does not lead to phosphorylation of ADP, despite of protons being pumped across the inner mt-membrane. Coupled respiration, therefore, is the coupled part of respiratory oxygen flux that pumps the fraction of protons across the inner mt-membrane which is utilized by the phosphorylation system to produce ATP from ADP and Pi. In the OXPHOS state, mitochondria are in a partially coupled state, and the corresponding coupled respiration is the free OXPHOS capacity. In the state of ROUTINE respiration, coupled respiration is the free ROUTINE activity.
Reference: Gnaiger 2014 MitoPathways
MitoPedia concepts: "MitoFit Quality Control System" is not in the list (MiP concept, Respiratory state, Respiratory control ratio, SUIT concept, SUIT protocol, SUIT A, SUIT B, SUIT C, SUIT state, Recommended, ...) of allowed values for the "MitoPedia concept" property.
MitoFit Quality Control System"MitoFit Quality Control System" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property.
MitoPedia methods:
Respirometry
MitoPedia topics: "Respiratory state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property. Respiratory state"Respiratory state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property.
