CZ Prague Jezek P

CZ Prague Jezek P

O2k-Network Lab	Institute of Physiology Laboratory . No. 75 Academy of Sciences of the Czech Republic
Address	Videnska 1083, 14220
City	Prague
State/Prov
Country	Czech Republic
Weblink
Contact	Jezek Petr
Team	Dlaskova Andrea, Dvorak Ales, Jaburek Martin, Jezek Jan, Plecita-Hlavata Lydie, Saudek Frantisek, Smolkova Katharina, Spacek Tomas, Uhrova Katerina, Zelenka Jaroslav, Pajuelo-Reguera David
Team previous
Status	2 Power-O2k 2004-
Oroboros Events	IOC125, MitoEAGLE 2017 CZ, MiP2014, MiP2013, IOC76, IOC44, IOC39, IOC24
Topics

O2k-Publications

	Published	Reference
Pavluch 2023 Sci Rep	2023	Pavluch V, Engstová H, Špačková J, Ježek P (2023) Deficiency of transcription factor Nkx6.1 does not prevent insulin secretion in INS-1E cells. https://doi.org/10.1038/s41598-023-27985-7
Pruuchova 2022 Antioxidants (Basel)	2022	Průchová P, Gotvaldová K, Smolková K, Alán L, Holendová B, Tauber J, Galkin A, Ježek P, Jabůrek M (2022) Antioxidant role and cardiolipin remodeling by redox-activated mitochondrial Ca²⁺-independent phospholipase A_2γ in the brain.
Plecita-Hlavata 2020 Antioxid Redox Signal	2020	Plecitá-Hlavatá L, Engstová H, Holendová B, Tauber J, Špaček T, Petrásková L, Křen V, Špačková J, Gotvaldová K, Ježek J, Dlasková A, Smolková K, Ježek P (2020) Mitochondrial superoxide production decreases on glucose-stimulated insulin secretion in pancreatic β cells due to decreasing mitochondrial matrix NADH/NAD⁺ ratio. Antioxid Redox Signal 33:789-815.
Leguina-Ruzzi 2020 Biomolecules	2020	Leguina-Ruzzi A, Vodičková A, Holendová B, Pavluch V, Tauber J, Engstová H, Dlasková A, Ježek P (2020) Glucose-induced expression of DAPIT in pancreatic β-cells. Biomolecules 10:E1026.
Smolkova 2020 Sci Rep	2020	Smolková K, Špačková J, Gotvaldová K, Dvořák A, Křenková A, Hubálek M, Holendová B, Vítek L, Ježek P (2020) SIRT3 and GCN5L regulation of NADP+- and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2 . Sci Rep 10:8677.
Kahancova 2020 Sci Rep	2020	Kahancová A, Sklenář F, Ježek P, Dlasková A (2020) Overexpression of native IF1 downregulates glucose-stimulated insulin secretion by pancreatic INS-1E cells. Sci Rep 10:1551.
Dlaskova 2019 Biochim Biophys Acta Bioenerg	2019	Dlasková A, Špaček T, Engstová H, Špačková J, Schröfel A, Holendová B, Smolková K, Plecitá-Hlavatá L, Ježek P (2019) Mitochondrial cristae narrowing upon higher 2-oxoglutarate load. Biochim Biophys Acta Bioenerg 1860:659-78.
Kahancova 2018 FEBS Lett	2018	Kahancova A, Sklenar F, Jezek P, Dlaskova A (2018) Regulation of glucose-stimulated insulin secretion by ATPase Inhibitory Factor 1 (IF1). FEBS Lett 592:999-1009.
Jezek 2017 Biochim Biophys Acta	2017	Ježek J, Engstová H, Ježek P (2017) Antioxidant mechanism of mitochondria-targeted plastoquinone SkQ1 is suppressed in aglycemic HepG2 cells dependent on oxidative phosphorylation. Biochim Biophys Acta 1858:750-62.
Zelenka 2016 Oxid Med Cell Longev	2016	Zelenka J, Dvořák A, Alán L, Zadinová M, Haluzík M, Vítek L (2016) Hyperbilirubinemia protects against aging-associated inflammation and metabolic deterioration. Oxid Med Cell Longev ID 6190609:10p.
Rohlenova 2016 Antioxid Redox Signal	2016	Rohlenova K, Sachaphibulkij K, Stursa J, Bezawork-Geleta A, Blecha J, Endaya B, Werner L, Cerny J, Zobalova R, Goodwin J, Spacek T, Alisadeh E, Yan B, Nguyen M, Vondrusova M, Sobol M, Jezek P, Hozak P, Truksa J, Rohlena J, Dong L, Neuzil J (2016) Selective disruption of respiratory supercomplexes as a new strategy to suppress Her2^high breast cancer. Antioxid Redox Signal 26:84-103.
Zelenka 2015 Oxid Med Cell Longev	2015	Zelenka J, Dvořák A, Alán L (2015) L-lactate protects skin fibroblasts against aging-associated mitochondrial dysfunction via mitohormesis. Oxid Med Cell Longev 2015:351698.
Plecita-Hlavata 2015 Am J Respir Cell Mol Biol	2015	Plecitá-Hlavatá L, Tauber J, Li M, Zhang H, Flockton AR, Pullamsetti SS, Chelladurai P, D'alessandro A, El Kasmi KC, Ježek P, Stenmark KR (2015) Constitutive reprogramming of fibroblast mitochondrial metabolism in pulmonary hypertension. Am J Respir Cell Mol Biol 55:47-57.
Plecita-Hlavata 2015 J Bioenerg Biomembr	2015	Plecitá-Hlavatá L, Ježek J, Ježek P (2015) Aglycemia keeps mitochondrial oxidative phosphorylation under hypoxic conditions in HepG2 cells. J Bioenerg Biomembr 47(6):467-76.
Smolkova 2015 Int J Biochem Cell Biol	2015	Smolková K, Dvořák A, Zelenka J, Vítek L, Ježek P (2015) Reductive carboxylation and 2-hydroxyglutarate formation by wild-type IDH2 in breast carcinoma cells. Int J Biochem Cell Biol 65:125-33.
Jezek 2015 Antioxid Redox Signal	2015	Ježek J, Dlasková A, Zelenka J, Jabůrek M, Ježek P (2015) H2O2-activated mitochondrial phospholipase iPLA2γ prevents lipotoxic oxidative stress in synergy with UCP2, amplifies signaling via G-protein-coupled receptor GPR40, and regulates insulin secretion in pancreatic β-cells. Antioxid Redox Signal 23:958-72.
Konickova 2014 Annals Hepatol	2014	Konickova R, Vankova K, Vanikova J, Vanova K, Muchova L, Subhanova I, Zadoinova M, Zelenka J, Dvorak A, Kolar M,Strnad H, Rimpelova S, Ruml T, Wong RJ, Vitek L (2014) Anti-cancer effects of blue-green alga Spirulina platensis, a natural source of bilirubin-like tetrapyrrolic compounds. Annals Hepatol 13:273-83.
MiPNet18.04 IOC76	2013-05-28	Prague CZ, 2013 May 28-29. Oroboros O2k-Workshop on high-resolution respirometry (HRR) and O2k-Fluorometry, IOC76. O2k-Network Lab »CZ Prague Kalous M.
Jaburek 2013 Int J Biochem Cell Biol	2013	Jabůrek M, Ježek J, Zelenka J, Ježek P (2013) Antioxidant activity by a synergy of redox-sensitive mitochondrial phospholipase A2 and uncoupling protein-2 in lung and spleen. Int J Biochem Cell Biol 45:816-25.
Smolkova 2010 J Bioenerg Biomembr	2010	Smolková K, Bellance N, Scandurra F, Génot E, Gnaiger E, Plecitá-Hlavatá L, Ježek P, Rossignol R (2010) Mitochondrial bioenergetic adaptations of breast cancer cells to aglycemia and hypoxia. https://doi.org/10.1007/s10863-009-9267-x
Jezek 2010 Physiol Res	2010	Ježek J, Jabůrek M, Zelenka J, Ježek P (2010) Mitochondrial phospholipase A₂ activated by reactive oxygen species in heart mitochondria induces mild uncoupling. Physiol Res 59:737-47.
Plecita-Hlavata 2009 Int J Biochem Cell Biol	2009	Plecita-Hlavata L, Jezek J, Jezek P (2009) Pro-oxidant mitochondrial matrix-targeted ubiquinone MitoQ₁₀ acts as anti-oxidant at retarded electron transport or proton pumping within Complex I. Int J Biochem Cell Biol 41:1697-707.
Bellance 2009 Int J Biochem Cell Biol	2009	Bellance N, Benard G, Furt F, Begueret H, Smolková K, Passerieux E, Delage JP, Baste JM, Moreau P, Rossignol R (2009) Bioenergetics of lung tumors: Alteration of mitochondrial biogenesis and respiratory capacity. Int J Biochem Cell Biol 41:2566-77.
Spacek 2008 Int J Biochem Cell Biol	2008	Spacek T, Santorová J, Zacharovová K, Berková Z, Hlavatá L, Saudek F, Jezek P (2008) Glucose-stimulated insulin secretion of insulinoma INS-1E cells is associated with elevation of both respiration and mitochondrial membrane potential. Int J Biochem Cell Biol 40:1522-35.
Hlavata 2008 Aging Cell	2008	Hlavatá L, Nachin L, Jezek P, Nyström T (2008) Elevated Ras/protein kinase A activity in Saccharomyces cerevisiae reduces proliferation rate and lifespan by two different reactive oxygen species-dependent routes. Aging Cell 7:148-57.
Dlaskova 2008 Int J Biochem Cell Biol	2008	Dlasková A, Hlavatá L, Jezek J, Jezek P (2008) Mitochondrial Complex I superoxide production is attenuated by uncoupling. Int J Biochem Cell Biol 40:2098-109.
Zacharovova 2005 Transplant Proc	2005	Zacharovova K, Berkova Z, Spacek T, Kriz J, Dovolilova E, Girman P, Koblas T, Jezek P, Saudek F (2005) In vitro assessment of pancreatic islet vitality by oxymetry. Transplant Proc 37:3454-6.

O2k-Abstracts

	Published	Reference
Pajuelo-Reguera 2017 MiP2017	2017	COX4-1/COX4-2 cell knock-out/knock-in models for the study of cytochrome c oxidase regulation.
Jaburek 2014 Abstract MiP2014	2014	The role of phospholipase A2γ in the regulation of mitochondrial uncoupling protein 2–dependent antioxidant function.
Jezek 2014 Abstract MiP2014	2014	Mitochondrial cristae morphology changes: from Hackenbrock to hypoxia.
Jezek 2013 Abstract MiP2013	2013	Ježek P, Ježek J, Zelenka J, Dlasková A, Jabůrek M (2013) Antioxidant synergy of mitochondrial uncoupling protein UCP2 and phospholipase iPLA2γ. Mitochondr Physiol Network 18.08.
Zelenka 2013 Abstract MiP2013	2013	Zelenka J, Smolkova K, Dvorak A, Vitek L, Jezek P (2013) Reverse carboxylation glutaminolysis in breast cancer cells. Mitochondr Physiol Network 18.08.
Zelenka J 2013 Abstract MiP2013	2013	Zelenka J, Alan L, Jezek P(2013) Response of cancer cells to mitochondrial DNA damage. Mitochondr Physiol Network 18.08.