Difference between revisions of "Bristot 2014 Abstract MiP2014"
From Bioblast
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|title=High-resolution respirometry and bioenergetics evaluation in fibrobalsts derived from patient with TP53 germline mutations. | |title=High-resolution respirometry and bioenergetics evaluation in fibrobalsts derived from patient with TP53 germline mutations. | ||
|info=[[File:Person.JPG|240px|right|Name]] [http://www.mitophysiology.org/index.php?mip2014 MiP2014], [[Laner 2014 Mitochondr Physiol Network MiP2014|Book of Abstracts Open Access]] | |info=[[File:Person.JPG|240px|right|Name]] [http://www.mitophysiology.org/index.php?mip2014 MiP2014], [[Laner 2014 Mitochondr Physiol Network MiP2014|Book of Abstracts Open Access]] | ||
|authors=Bristot | |authors=Bristot IJ, Macedo G, Neto CB, Ashton-Prolla P, Klamt F | ||
|year=2014 | |year=2014 | ||
|event=MiP2014 | |event=MiP2014 | ||
| Line 9: | Line 9: | ||
|area=Respiration | |area=Respiration | ||
|organism=Human | |organism=Human | ||
|model cell lines=Fibroblast | |model cell lines=Fibroblast | ||
|preparations=Intact cells | |preparations=Intact cells | ||
|injuries=RONS; Oxidative Stress | |injuries=RONS; Oxidative Stress | ||
|diseases=Cancer | |diseases=Cancer | ||
| | |couplingstates=LEAK, OXPHOS | ||
| | |instruments=Oxygraph-2k | ||
|additional=MiP2014 | |additional=MiP2014 | ||
}} | }} | ||
== Affiliation == | == Affiliation == | ||
1-Progr PĂłs-Gradua CiĂȘncias Biol: BioquĂmica, UFRGS; 2-Inst Nacionais CiĂȘncia e Tecnol - Translac Medicina; 3-Progr PĂłs-Gradua GenĂ©t Biol Mol, Univ Federal Rio Grande do Sul (UFRGS); 4-Lab Medicina GenĂŽmica, Hosp ClĂnicas Porto Alegre HCPA; 5-Rede GaĂșcha Estresse Oxidativo e Sinalização Celular; 6-Progr de PĂłs-Gradua CiĂȘncias MĂ©dicas: Medicina, UFRGS, 7Serviço de GenĂ©tica MĂ©dica, HCPA; Porto Alegre, Brazil. - [email protected] | 1-Progr PĂłs-Gradua CiĂȘncias Biol: BioquĂmica, UFRGS; 2-Inst Nacionais CiĂȘncia e Tecnol - Translac Medicina; 3-Progr PĂłs-Gradua GenĂ©t Biol Mol, Univ Federal Rio Grande do Sul (UFRGS); 4-Lab Medicina GenĂŽmica, Hosp ClĂnicas Porto Alegre HCPA; 5-Rede GaĂșcha Estresse Oxidativo e Sinalização Celular; 6-Progr de PĂłs-Gradua CiĂȘncias MĂ©dicas: Medicina, UFRGS, 7Serviço de GenĂ©tica MĂ©dica, HCPA; Porto Alegre, Brazil. - [email protected] | ||
== References == | |||
# Olivier M, Goldgar DE, Sodha N, Ohgaki H, Kleihues P, Hainaut P, Eeles RA (2003) LiFraumeni and related syndromes: correlation between tumor type, family structure, and TP53 genotype. Cancer Res 63: 6643â50. | |||
# Latronico AC, Pinto EM, Domenice S, Fragoso MC, Martin RM, Zerbini MC, Lucon AM, Mendonca BB (2001) An inherited mutation outside the highly conserved DNA-binding domain of the p53 tumor suppressor protein in children and adults with sporadic adrenocortical tumors. J Clin Endocrinol Metab 86: 4970â3. | |||
# Cantor JR, Sabatini DM ( 2012) Cancer cell metabolism: one hallmark, many faces. Cancer Discov 2: 881â98. | |||
# Macedo GS, LisbĂŽa da Motta L, Giacomazzi J, Netto CB, Manfredini V, Vanzin CS, Vargas CR, Hainaut P, Klamt F, Ashton-Prolla P (2012) Increased oxidative damage in carriers of the germline. TP53 p.R337H mutation. PLoS One 7:e47010. | |||
Revision as of 12:18, 8 August 2014
| High-resolution respirometry and bioenergetics evaluation in fibrobalsts derived from patient with TP53 germline mutations. |
Link:
MiP2014, Book of Abstracts Open Access
Bristot IJ, Macedo G, Neto CB, Ashton-Prolla P, Klamt F (2014)
Event: MiP2014
Labels: MiParea: Respiration Pathology: Cancer Stress:RONS; Oxidative Stress"RONS; Oxidative Stress" is not in the list (Cell death, Cryopreservation, Ischemia-reperfusion, Permeability transition, Oxidative stress;RONS, Temperature, Hypoxia, Mitochondrial disease) of allowed values for the "Stress" property. Organism: Human
Preparation: Intact cells
Coupling state: LEAK, OXPHOS
HRR: Oxygraph-2k
MiP2014
Affiliation
1-Progr PĂłs-Gradua CiĂȘncias Biol: BioquĂmica, UFRGS; 2-Inst Nacionais CiĂȘncia e Tecnol - Translac Medicina; 3-Progr PĂłs-Gradua GenĂ©t Biol Mol, Univ Federal Rio Grande do Sul (UFRGS); 4-Lab Medicina GenĂŽmica, Hosp ClĂnicas Porto Alegre HCPA; 5-Rede GaĂșcha Estresse Oxidativo e Sinalização Celular; 6-Progr de PĂłs-Gradua CiĂȘncias MĂ©dicas: Medicina, UFRGS, 7Serviço de GenĂ©tica MĂ©dica, HCPA; Porto Alegre, Brazil. - [email protected]
References
- Olivier M, Goldgar DE, Sodha N, Ohgaki H, Kleihues P, Hainaut P, Eeles RA (2003) LiFraumeni and related syndromes: correlation between tumor type, family structure, and TP53 genotype. Cancer Res 63: 6643â50.
- Latronico AC, Pinto EM, Domenice S, Fragoso MC, Martin RM, Zerbini MC, Lucon AM, Mendonca BB (2001) An inherited mutation outside the highly conserved DNA-binding domain of the p53 tumor suppressor protein in children and adults with sporadic adrenocortical tumors. J Clin Endocrinol Metab 86: 4970â3.
- Cantor JR, Sabatini DM ( 2012) Cancer cell metabolism: one hallmark, many faces. Cancer Discov 2: 881â98.
- Macedo GS, LisbĂŽa da Motta L, Giacomazzi J, Netto CB, Manfredini V, Vanzin CS, Vargas CR, Hainaut P, Klamt F, Ashton-Prolla P (2012) Increased oxidative damage in carriers of the germline. TP53 p.R337H mutation. PLoS One 7:e47010.
