Difference between revisions of "Blier 2013 Abstract MiP2013"
Beno Marija (talk | contribs) |
|||
| (6 intermediate revisions by 5 users not shown) | |||
| Line 1: | Line 1: | ||
{{Abstract | {{Abstract | ||
|title=Blier PU, Lemieux H, Pichaud N (2013) Holding our breath in our modern world: are mitochondria keeping the pace with global changes? Mitochondr Physiol Network 18.08. | |title=Blier PU, Lemieux H, Pichaud N (2013) Holding our breath in our modern world: are mitochondria keeping the pace with global changes? Mitochondr Physiol Network 18.08. | ||
|info=[ | |info=[[File:BlierP.jpg|150px|right|Pierre Blier]][[MiP2013]], [[Laner 2013 Mitochondr Physiol Network MiP2013|Book of Abstracts Open Access]] | ||
|authors=Blier PU, Lemieux H, Pichaud N | |authors=Blier PU, Lemieux H, Pichaud N | ||
|year=2013 | |year=2013 | ||
|event= | |event=MiPNet18.08_MiP2013 | ||
|abstract=Changes in environmental temperature can pose significant challenges to animals. Shifts in thermal habitat have been shown to be a major force driving species adaptation. These adaptations have been the focus of major research efforts to delineate the physiological or metabolic constraints related to temperature and to reveal the phenotypic characters that can or should adjust. Considering the current consensus on climate change, the focus of research will likely move on questioning if they will survive to future modifications of their thermal niches. Adjustments to temperature can either be through physiological plasticity (e.g. acclimation) or via genetic adaptation. Therefore we will have to specify what are the genetic and phenotypic attributes (at the level of individual, population and species) that could grant survival success. These questions are particularly important for ectotherms, which are in thermal equilibrium with the surrounding environment. To start answering these queries, we should wonder if any physiological or metabolic function set the temperature impact on organisms. Some recent developments point to mitochondria as a key metabolic structure that partly delineates the thermal range that organism can tolerate [1]. The catalytic capacity of mitochondria is highly sensitive to thermal variation and therefore should partly dictate the temperature dependence of biological functions. Mitochondria are a complex network of pathways of different enzymatic reactions that synergistically interact. The fine regulation of both ATP and ROS production depends on this integration of different enzymes and pathways. Here, we will scrutinize the temperature dependence of different parts of the mitochondrial pathways and evaluate the evolutionary challenges that should be overcome to insure mitochondrial adaptations to new thermal environments. | |abstract=Changes in environmental temperature can pose significant challenges to animals. Shifts in thermal habitat have been shown to be a major force driving species adaptation. These adaptations have been the focus of major research efforts to delineate the physiological or metabolic constraints related to temperature and to reveal the phenotypic characters that can or should adjust. Considering the current consensus on climate change, the focus of research will likely move on questioning if they will survive to future modifications of their thermal niches. Adjustments to temperature can either be through physiological plasticity (e.g. acclimation) or via genetic adaptation. Therefore we will have to specify what are the genetic and phenotypic attributes (at the level of individual, population and species) that could grant survival success. These questions are particularly important for ectotherms, which are in thermal equilibrium with the surrounding environment. To start answering these queries, we should wonder if any physiological or metabolic function set the temperature impact on organisms. Some recent developments point to mitochondria as a key metabolic structure that partly delineates the thermal range that organism can tolerate [1]. The catalytic capacity of mitochondria is highly sensitive to thermal variation and therefore should partly dictate the temperature dependence of biological functions. Mitochondria are a complex network of pathways of different enzymatic reactions that synergistically interact. The fine regulation of both ATP and ROS production depends on this integration of different enzymes and pathways. Here, we will scrutinize the temperature dependence of different parts of the mitochondrial pathways and evaluate the evolutionary challenges that should be overcome to insure mitochondrial adaptations to new thermal environments. | ||
|mipnetlab=CA Rimouski Blier PU, CA Edmonton Lemieux H | |mipnetlab=CA Rimouski Blier PU, CA Edmonton Lemieux H | ||
| Line 10: | Line 10: | ||
{{Labeling | {{Labeling | ||
|area=Respiration, Comparative MiP;environmental MiP | |area=Respiration, Comparative MiP;environmental MiP | ||
| | |organism=Other invertebrates | ||
|topics=Temperature | |topics=Temperature | ||
|couplingstates=OXPHOS | |couplingstates=OXPHOS | ||
| Line 16: | Line 16: | ||
|additional=MiP2013, S04 | |additional=MiP2013, S04 | ||
}} | }} | ||
== Affiliations and author contributions == | == Affiliations and author contributions == | ||
1 - Laboratoire de physiologie integrative, Dépt de Biologie Université du Québec, Canada; | 1 - Laboratoire de physiologie integrative, Dépt de Biologie Université du Québec, Canada; | ||
Latest revision as of 11:03, 28 April 2017
| Blier PU, Lemieux H, Pichaud N (2013) Holding our breath in our modern world: are mitochondria keeping the pace with global changes? Mitochondr Physiol Network 18.08. |
Link:
MiP2013, Book of Abstracts Open Access
Blier PU, Lemieux H, Pichaud N (2013)
Event: MiPNet18.08_MiP2013
Changes in environmental temperature can pose significant challenges to animals. Shifts in thermal habitat have been shown to be a major force driving species adaptation. These adaptations have been the focus of major research efforts to delineate the physiological or metabolic constraints related to temperature and to reveal the phenotypic characters that can or should adjust. Considering the current consensus on climate change, the focus of research will likely move on questioning if they will survive to future modifications of their thermal niches. Adjustments to temperature can either be through physiological plasticity (e.g. acclimation) or via genetic adaptation. Therefore we will have to specify what are the genetic and phenotypic attributes (at the level of individual, population and species) that could grant survival success. These questions are particularly important for ectotherms, which are in thermal equilibrium with the surrounding environment. To start answering these queries, we should wonder if any physiological or metabolic function set the temperature impact on organisms. Some recent developments point to mitochondria as a key metabolic structure that partly delineates the thermal range that organism can tolerate [1]. The catalytic capacity of mitochondria is highly sensitive to thermal variation and therefore should partly dictate the temperature dependence of biological functions. Mitochondria are a complex network of pathways of different enzymatic reactions that synergistically interact. The fine regulation of both ATP and ROS production depends on this integration of different enzymes and pathways. Here, we will scrutinize the temperature dependence of different parts of the mitochondrial pathways and evaluate the evolutionary challenges that should be overcome to insure mitochondrial adaptations to new thermal environments.
• O2k-Network Lab: CA Rimouski Blier PU, CA Edmonton Lemieux H
Labels: MiParea: Respiration, Comparative MiP;environmental MiP
Organism: Other invertebrates
Regulation: Temperature Coupling state: OXPHOS
HRR: Oxygraph-2k
MiP2013, S04
Affiliations and author contributions
1 - Laboratoire de physiologie integrative, Dépt de Biologie Université du Québec, Canada;
2 - Campus Saint-Jean, University of Alberta, Edmonton, Canada.
Email: [email protected]
References
- Pörtner HO, Bennett AF, Bozinovic F, Clarke A, Lardies MA, Lucassen, M, Pelster B, Schiemer F, Stillman, JH (2006) Trade-offs in thermal adaptation: The need for a molecular to ecological integration. Physiol Biochem Zool 79: 295-313.
