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Difference between revisions of "Background state"

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{{MitoPedia
{{MitoPedia
|abbr=''Y''
|abbr=''Y''
|description=The '''background state''', ''Y'', is the non-activated or inhibited respiratory state at background flux, which is low in relation to the higher flux in the [[reference state]], ''Z''. The transition from the background state to the reference state is a step change. A [[metabolic control variable]], ''X'' (substrate, activator), is added to the background state to stimulate flux to the level of the reference state. Alternatively, the metabolic control variable, ''X'', is an inhibitor, which is present in the background state, ''Y'', but absent in the reference state, ''Z''. The background state is the baseline of a single step in the definition of the [[flux control factor]]. In a sequence of step changes, the common [[baseline state]] is the state of lowest flux in relation to all steps, which can be used as a [[baseline correction]].
|description=The '''background state''' Y (background rate ''Y<sub>X</sub>'') is the non-activated or inhibited respiratory state at background rate, which is low in relation to the higher rate ''Z<sub>X</sub>'' in the [[reference state]] Z. The transition from the background state to the reference state is a step change. A [[metabolic control variable]] ''X'' (substrate, activator) is added to the background state to stimulate flux to the level of the reference state. Alternatively, the metabolic control variable ''X'' is an inhibitor, which is present in the background state Y, but absent in the reference state Z. The background state is the baseline of a single step in the definition of the [[flux control efficiency]]. In a sequence of step changes, the common [[baseline state]] is the state of lowest flux in relation to all steps, which can be used as a [[baseline correction]].
|info=[[Flux control factor]]
|info=[[Flux control efficiency]]
}}
}}
Communicated by [[Gnaiger Erich]] (2013-08-01) edited 2020-11-10.
{{MitoPedia concepts
{{MitoPedia concepts
|mitopedia concept=Respiratory state, Recommended
|mitopedia concept=Respiratory state, Recommended
}}
}}
{{MitoPedia methods}}
{{MitoPedia O2k and high-resolution respirometry}}
{{MitoPedia topics
{{MitoPedia topics
|mitopedia topic=EAGLE
|mitopedia topic=EAGLE
}}
}}
Communicated by [[Gnaiger E]] 2013-08-01; edited 2016-11-19.

Latest revision as of 17:19, 10 November 2020


high-resolution terminology - matching measurements at high-resolution


Background state

Description

The background state Y (background rate YX) is the non-activated or inhibited respiratory state at background rate, which is low in relation to the higher rate ZX in the reference state Z. The transition from the background state to the reference state is a step change. A metabolic control variable X (substrate, activator) is added to the background state to stimulate flux to the level of the reference state. Alternatively, the metabolic control variable X is an inhibitor, which is present in the background state Y, but absent in the reference state Z. The background state is the baseline of a single step in the definition of the flux control efficiency. In a sequence of step changes, the common baseline state is the state of lowest flux in relation to all steps, which can be used as a baseline correction.

Abbreviation: Y

Reference: Flux control efficiency

Communicated by Gnaiger Erich (2013-08-01) edited 2020-11-10.


MitoPedia concepts: Respiratory state, Recommended 


MitoPedia topics: EAGLE