Wu 2020 Chemosphere
| Wu F, Sokolov EP, Dellwig O, Sokolova IM (2020) Season-dependent effects of ZnO nanoparticles and elevated temperature on bioenergetics of the blue mussel Mytilus edulis. Chemosphere 263:127780. |
Wu Fangli, Sokolov Eugene P, Dellwig Olaf, Sokolova Inna M (2020) Chemosphere
Abstract: Input of ZnO nanoparticles (nZnO) from multiple sources have raised concerns about the potential toxic effects on estuarine and coastal organisms. The toxicity of nZnO and its interaction with common abiotic stressors (such as elevated temperature) are not well understood in these organisms. Here, we examined the bioenergetics responses of the blue mussel Mytilus edulis exposed for 21 days to different concentrations of nZnO or dissolved zinc (Zn2+) (0, 10, 100 ΞΌg l-1) and two temperatures (ambient and 5 Β°C warmer) in winter and summer. Exposure to nZnO had little effect on the protein and lipid levels, but led to a significant depletion of carbohydrates and a decrease in the electron transport system (ETS) activity. Qualitatively similar but weaker effects were found for dissolved Zn. In winter mussels, elevated temperature (15 Β°C) led to elevated protein and lipid levels increasing the total energy content of the tissues. In contrast, elevated temperature (20 Β°C) resulted in a decrease in the lipid and carbohydrate levels and suppressed ETS in summer mussels. These data indicate that moderate warming in winter (but not in summer) might partially compensate for the bioenergetics stress caused by nZnO toxicity in M. edulis from temperate areas such as the Baltic Sea. β’ Keywords: Carbohydrate, Electron transport activity, Energy reserves, Lipid, Mitochondria, Mussel, Oxidative phosphorylation, Proton leak, Warming, nZnO β’ Bioblast editor: Plangger M β’ O2k-Network Lab: DE Rostock Sokolova I
Labels: MiParea: Respiration, Pharmacology;toxicology
Stress:Temperature Organism: Molluscs Tissue;cell: Other cell lines Preparation: Isolated mitochondria
Coupling state: LEAK, OXPHOS, ET
Pathway: N, NS
HRR: Oxygraph-2k
2020-08
