Wiesner RJ

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MiPsociety
COST Action CA15203 MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping


 

Wiesner RJ


MitoPedia topics: EAGLE 

COST: Member COST WG1: WG1


Name Wiesner Rudolf J, Prof. Dr.
Institution
Wiesner Rudolf
Institute for Vegetative Physiology,

Universtiy of Cologne, DE

Address Robert-Koch-Str. 39, 50931
City Cologne
State/Province
Country Germany
Email rudolf.wiesner@uni-koeln.de
Weblink
O2k-Network Lab


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Publications

 PublishedReference
Gnaiger 2019 MitoFit Preprint Arch2019Gnaiger E, Aasander Frostner E, Abdul Karim N, Abdel-Rahman EA, Abumrad NA, Acuna-Castroviejo D, Adiele RC, et al (2019) Mitochondrial respiratory states and rates. MitoFit Preprint Arch doi:10.26124/mitofit:190001.v6.
Schommers 2017 Mol Metab2017Schommers P, Thurau A, Bultmann-Mellin I, Guschlbauer M, Klatt AR, Rozman J, Klingenspor M, de Angelis MH, Alber J, Gründemann D, Sterner-Kock A, Wiesner RJ (2017) Metformin causes a futile intestinal-hepatic cycle which increases energy expenditure and slows down development of a type 2 diabetes-like state. Mol Metab 6:737-47.
Franko 2016 Diabetes2016Franko A, Huypens P, Neschen S, Irmler M, Rozman J, Rathkolb B, Neff F, Prehn C, Dubois G, Baumann M, Massinger R, Gradinger D, Przemeck GK, Repp B, Aichler M, Feuchtinger A, Schommers P, Stöhr O, Sanchez-Lasheras C, Adamski J, Peter A, Prokisch H, Beckers J, Walch AK, Fuchs H, Wolf E, Schubert M, Wiesner RJ, Hrabě de Angelis M (2016) Bezafibrate improves insulin sensitivity and metabolic flexibility in STZ-treated diabetic mice. Diabetes 65:2540-52.
Szczepanowska 2016 EMBO J2016Szczepanowska K, Maiti P, Kukat A, Hofsetz E, Nolte H, Senft K, Becker C, Ruzzenente B, Hornig-Do HT, Wibom R, Wiesner RJ, Krüger M, Trifunovic A (2016) CLPP coordinates mitoribosomal assembly through the regulation of ERAL1 levels. EMBO J 35:2566-83.
Freyer 2012 Nat Genet2012Freyer C, Cree LM, Mourier A, Stewart JB, Koolmeister C, Milenkovic D, Wai T, Floros VI, Hagström E, Chatzidaki EE, Wiesner RJ, Samuels DC, Larsson NG, Chinnery PF (2012) Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission. Nat Genet 44:1282-5.
Franko 2012 J Mol Med2012Franko A, von Kleist-Retzow JC, Böse M, Sanchez-Lasheras C, Brodesser S, Krut O, Kunz WS, Wiedermann D, Höhn M, Stöhr O, Moll L, Freude S, Krone W, Schubert M, Wiesner RJ (2012) Complete failure of insulin-transmitted signaling, but not obesity-induced insulin resistance, impairs respiratory chain function in muscle. J Mol Med 90:1145-60.
Wiesner 1988 Biochim Biophys Acta1988Wiesner RJ, Kreutzer U, Rösen P, Grieshaber MK (1988) Subcellular distribution of malate-aspartate cycle intermediates during normoxia and anoxia in the heart. Biochim Biophys Acta 936:114-23.

Abstracts

 PublishedReference
Kimoloi 2019 MiPschool Coimbra2019
MiPsociety
Mitochondrial DNA (mtDNA) maintenance defects impairs muscle stem cells regenerative efficiency.
Wiesner 2018 MiPschool Tromso E12018
MiPsociety
Aging-related accumulation of mitochondrial DNA deletions in skeletal muscle occurs preferentially in Type IIb fibers – high mitophagic flux protects Type I fibers.

Participated at