Walley 2009 Nat Rev Genet

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Walley AJ, Asher JE, Froguel P (2009) The genetic contribution to non-syndromic human obesity. Nat Rev Genet 10:431–42.

» PMID: 19506576 Open Access

Walley AJ, Asher JE, Froguel P (2009) Nat Rev Genet

Abstract: The last few years have seen major advances in common non-syndromic obesity research, much of it the result of genetic studies. This Review outlines the competing hypotheses about the mechanisms underlying the genetic and physiological basis of obesity, and then examines the recent explosion of genetic association studies that have yielded insights into obesity, both at the candidate gene level and the genome-wide level. With obesity genetics now entering the post-genome-wide association scan era, the obvious question is how to improve the results obtained so far using single nucleotide polymorphism markers and how to move successfully into the other areas of genomic variation that may be associated with common obesity.

Bioblast editor: Gnaiger E

Labels: MiParea: nDNA;cell genetics  Pathology: Obesity 

Organism: Human 

Preparation: Intact organism