US FL Orlando Sparks LM

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US FL Orlando Sparks LM

Oroboros O2k-Network

O2k-Network
O2k-Network Lab Translational Research Institute for Metabolism and Diabetes

Burnham Institute for Medical Research

Power-O2k Network Cluster: US FL Orlando Translational Research Institute

Address 301 East Princeton Street, 32827
City Orlando
State/Prov Florida (FL)
Country USA
Weblink
Contact Sparks Lauren M
Team McCall J, Nelson Dinielle, Pino Maria F, Smith Steven R, Stephens Natalie
Team previous Costford Sheila
Status 2 Power-O2k 2012-
Oroboros Events MiPschool 2015, IOC104, MiP2014, MiP2013 , IOC80, IOC79, IOC72, MiPschool 2009, MiPsummer 2009
Topics Obesity, T2 Diabetes


O2k-Publications

 PublishedReference
Brouwers 2018 Front Physiol2018Brouwers B, Stephens NA, Costford SR, Hopf ME, Ayala JE, Yi F, Xie H, Li JL, Gardell SJ, Sparks LM, Smith SR (2018) Elevated nicotinamide phosphoribosyl transferase in skeletal muscle augments exercise performance and mitochondrial respiratory capacity following exercise training. Front Physiol 9:704.
Pino 2017 Int J Obes (Lond)2017Pino MF, Divoux A, Simmonds AV, Smith SR, Sparks LM (2017) Investigating the effects of Orexin-A on thermogenesis in human deep neck brown adipose tissue. Int J Obes (Lond) 41:1646-53.
Sparks 2016 Diabetologia2016Sparks LM, Gemmink A, Phielix E, Bosma M, Schaart G, Moonen-Kornips E, Jörgensen JA, Nascimento EB, Hesselink MK, Schrauwen P, Hoeks J (2016) ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity. Diabetologia 59:1030-9.
Van de Weijer 2015 Diabetes2015van de Weijer T, Phielix E, Bilet L, Williams EG, Ropelle ER, Bierwagen A, Livingstone R, Nowotny P, Sparks LM, Paglialunga S, Szendroedi J, Havekes B, Moullan N, Pirinen E, Hwang JH, Schrauwen-Hinderling VB, Hesselink MK, Auwerx J, Roden M, Schrauwen P (2015) Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans. Diabetes 64:1193-201.
Coen 2015 Diabetes2015Coen PM, Menshikova EV, Distefano G, Zheng D, Tanner CJ, Standley RA, Helbling NL, Dubis GS, Ritov VB, Xie H, Desimone ME, Smith SR, Stefanovic-Racic M, Toledo FG, Houmard JA, Goodpaster BH (2015) Exercise and weight loss improve muscle mitochondrial respiration, lipid partitioning, and insulin sensitivity after gastric bypass surgery. Diabetes 64:3737-50.
Vijgen 2013 J Clin Endocrinol Metab2013Vijgen GH, Sparks LM, Bouvy ND, Schaart G, Hoeks J, van Marken Lichtenbelt WD, Schrauwen P (2013) Increased oxygen consumption in human adipose tissue from the "brown adipose tissue" region. J Clin Endocrinol Metab 98:E1230-4.
Bosma 2012 Histochem Cell Biol2012Bosma M, Minnaard R, Sparks LM, Schaart G, Losen M, de Baets MH, Duimel H, Kersten S, Bickel PE, Schrauwen P, Hesselink MK (2012) The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria. Histochem Cell Biol 137:205-16.
Phielix 2012 Diabetes2012Phielix E, Meex R, Ouwens DM, Sparks LM, Hoeks J, Schaart G, Moonen-Kornips E, Hesselink MK, Schrauwen P (2012) High oxidative capacity due to chronic exercise training attenuates lipid-induced insulin resistance. Diabetes 61:2472-8.

O2k-Abstracts

 PublishedReference
Sparks 2014 Abstract MiP20142014NAMPT remodels substrate metabolism in skeletal muscle.

Pictures of the Oxygraphs at the TRI-Translational Research Institute for Metabolism and Diabetes:

Sparks L Lab2.JPG Sparks L Lab4.JPG


* pictures by Lauren Sparks