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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping
Szabadkai Gyorgy
MitoPedia topics: EAGLE
COST: Member
COST WG2: WG2
| Name | Szabadkai Gyorgy, MD, PhD
Senior Lecturer |
|---|---|
| Institution | Department of Cell and Developmental Biology
Consortium for Mitochondrial Research (CfMR) University College London |
| Address | Gower Street, WC1E 6BT |
| City | London |
| State/Province | |
| Country | United Kingdom |
| [email protected] | |
| Weblink | |
| O2k-Network Lab |
Labels:
Field of research: Basic
Publications
| Published | Reference | |
|---|---|---|
| Menegollo 2019 Methods Mol Biol | 2019 | Menegollo M, Tessari I, Bubacco L, Szabadkai G (2019) Determination of ATP, ADP, and AMP Levels by Reversed-Phase High-Performance Liquid Chromatography in Cultured Cells. Methods Mol Biol 1925:223-32. |
| Briston 2017 Sci Rep | 2017 | Briston T, Roberts M, Lewis S, Powney B, M Staddon J, Szabadkai G, Duchen MR (2017) Mitochondrial permeability transition pore: sensitivity to opening and mechanistic dependence on substrate availability. Sci Rep 7:10492. |
| Selwood 2017 US Patent | 2017 | Selwood DL, Baker D, Szabadkai G, Duchen MR, Hill JM, Warne JND (2017) Quinolium conjugates of cyclosporin. US Patent US20170349632 A1. |
| Briston 2016 Sci Rep | 2016 | Briston T, Lewis S, Koglin M, Mistry K, Shen Y, Hartopp N, Katsumata R, Fukumoto H, Duchen MR, Szabadkai G, Staddon JM, Roberts M, Powney B (2016) Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria. Sci Rep 6:37798. |
| Warne 2015 J Biol Chem | 2015 | Warne J, Pryce G, Hill JM, Shi X, Lennerås F, Puentes F, Kip M, Hilditch L, Walker P, Simone MI, Chan AWE, Towers GJ, Coker AR, Duchen MR, Szabadkai G, Baker D, Selwood DL (2015) Selective inhibition of the mitochondrial permeability transition pore protects against neuro-degeneration in experimental multiple sclerosis. J Biol Chem 291:4356-73. |
| Logan 2014 Nat Genet | 2014 | Logan CV, Szabadkai G, Sharpe JA, Parry DA, Torelli S, Childs AM, Kriek M, Phadke R, Johnson CA, Roberts NY, Bonthron DT, Pysden KA, Whyte T, Munteanu I, Foley AR, Wheway G, Szymanska K, Natarajan S, Abdelhamed ZA, Morgan JE, Roper H, Santen GW, Niks EH, van der Pol WL, Lindhout D, Raffaello A, De Stefani D, den Dunnen JT, Sun Y, Ginjaar I, Sewry CA, Hurles M, Rizzuto R. UK10K Consortium, Duchen MR, Muntoni F, Sheridan E (2014) Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling. Nat Genet 46:188-93. |
| Astin 2013 Sci Rep | 2013 | Astin R, Bentham R, Djafarzadeh S, Horscroft JA, Kuc RE, Leung PS, Skipworth JR, Vicencio JM, Davenport AP, Murray AJ, Takala J, Jakob SM, Montgomery H, Szabadkai G (2013) No evidence for a local renin-angiotensin system in liver mitochondria. Sci Rep 3:2467. |
Abstracts
| Published | Reference | |
|---|---|---|
| Matteo 2015 Abstract MiPschool London 2015 | 2015 | Mitochondrial and nuclear IP3-mediated Ca2+ signaling in core myopathies. |
| Bentham 2015 Abstract MiPschool London 2015 | 2015 | Specific mitochondrial biogenesis patterns underlie development of breast cancer subtypes. |
| Logan 2015 Abstract MiPschool London 2015 | 2015 | Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signalling. |
| Hill 2015 Abstract MiPschool London 2015 | 2015 | A novel inhibitor of the mitochondrial permeability transition pore is beneficial in an experimental model of multiple sclerosis. |
| Duchen 2012 Abstract Bioblast | 2012 | Blacker TS, Gale JE, Ziegler M, Bain AJ, Szabadkai G, Duchen MR (2012) Separation of NADPH and NADH fluorescence emission in live cells using fluorescence lifetime imaging microscopy. Mitochondr Physiol Network 17.12. |
