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...) in C2C12 cells in a dose-dependent manner. At a concentration of 0.2 μM, paxilline, which effectively abolished the protective effect of NS1619, failed to cou

...was reversed by preincubation with the BK_Ca channel inhibitors paxilline and Iberiotoxin (IbTx). Moreover, mitochondrial respiration measurements re

...ium channel blockers 5-hydroxy decanoic acid (5HD) blocking mitoK(ATP) and paxilline (PAX) blocking mitoK(Ca) abolished cardioprotective effect of Hp (Hp + 5HD

...where this effect was partially abolished by the mitoBKCa channel blocker paxilline. In conclusion, these results suggest that luteolin has cardioprotective ef

...ty to Ca²⁺, [[NS1619]] (a BK_Ca channel opener) and [[paxilline]] (BK_Ca channel inhibitor) indicate similarity to the mammalian

...w calcium concentration. Additionally, the channel activity was blocked by paxilline (inhibitor of the BKCa types channels). Moreover we demonstrated that the p

...clamp technique. The mitoBK_Ca channel activity was inhibited by paxilline, potassium channel blocker. The channel was activated by Ca₂₊ an

...us concentrations is not inhibited by the main inhibitor for this channel, paxilline. Possible cytoprotective properties of flavonoids with using apoptosis/necr

...ive roles of mitoBKs. Herein, we present electrophysiological evidence for paxilline- and NS11021-sensitive BK-mediated currents of 190 pS conductance in mitopl