Silaidos C

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COST Action CA15203 MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping


Silaidos C

MitoPedia topics: EAGLE 

COST: Member COST WG1: WG1


Name Silaidos Carmina,
Institution Department of Nutrition in Prevention & Therapy
Silaidos Carmina

Justus Liebig University

Institute of Nutrional Sciences

Address Wilhelmstr. 20, 35392
City Gießen
Country Germany
O2k-Network Lab DE Frankfurt Eckert GP, DE Giessen Eckert GP



MitoEAGLE blood cells 12018MitoEAGLE blood cells group (2018) An interlaboratory guide through procedures for mitochondrial respiratory studies with intact and permeabilized peripheral blood mononuclear cells and platelets. - Updated: 2018-02-23
Silaidos 2018 Biol Sex Differ2018Silaidos C, Pilatus U, Grewal R, Matura S, Lienerth B, Pantel J, Eckert GP (2018) Sex-associated differences in mitochondrial function in human peripheral blood mononuclear cells (PBMCs) and brain. Biol Sex Differ 9:34.
Reutzel 2018 Oxid Med Cell Longev2018Reutzel M, Grewal R, Silaidos C, Zotzel J, Marx S, Tretzel J, Eckert GP (2018) Effects of long-term treatment with a blend of highly purified olive secoiridoids on cognition and brain ATP levels in aged NMRI mice. Oxid Med Cell Longev 2018:4070935.
Asseburg 2016 Neuromolecular Med2016Asseburg H, Schäfer C, Müller M, Hagl S, Pohland M, Berressem D, Borchiellini M, Plank C, Eckert GP (2016) Effects of grape skin extract on age-related mitochondrial dysfunction, memory and life span in C57BL/6J mice. Neuromolecular Med 18:378-95.


Calabria 2019 MiPschool Coimbra2019
Elisa Calabria
Investigating mitochondrial function in blood cells by high-resolution respirometry: contribution to an interlaboratory study. Mitoeagle WG4.

MitoEAGLE Short-Term Scientific Mission

Work Plan summary
The aim of the STSM to the workshop in Lund is to dilate my knowledge of working with PBMCs and to interact with other scientists in the field. In addition, the workshop will provide a joint WG4 blood cell manuscript entitled "An interlaboratory guide through procedures for mitochondrial respiratory studies with intact and permeabilized peripheral blood mononuclear cells and platelets" to standardize the PBMC methodology for the international community. The knowledge and experience of the various working groups will combined in this paper to improve the work with PBMCs. Since I have already gained a lot of experience in working with PBMCs in the last few years and have already been completed several experiments with PBMCs, I would like to use my knowledge and my results to contribute to the success of the paper. The collaboration of several working groups on the manuscript gives a unique opportunity to jointly publish and compare data. This makes it easier for beginners to work with PBMCs and saving research funds, since duplicate attempts are avoided. In addition, standardizing the method leads to a better (interlaboratory) comparability of the results. In order to achieve my proposed aims, I will communicate with the other scientists and discuss our findings. We also want to continue the active work on the paper and bring it to a final version.

Participated at