Name | Ryan Terence E., PhD
PostDoc |
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Institution | Dept. of Applied Physiology & Kinesiology
University of Florida |
Address | 100 Farrior Hall at 205 Fletcher Drive, 32611 |
City | Gainesville |
State/Province | Florida (FL) |
Country | USA |
[email protected] | |
Weblink | |
O2k-Network Lab | US FL Gainesville Ryan TE, US NC Greenville Neufer PD |
Labels:
Publications
Published | Reference | |
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Thome 2024 JCI Insight | 2024 | Thome T, Vugman NA, Stone LE, Wimberly K, Scali ST, Ryan TE (2024) A tryptophan-derived uremic metabolite-Ahr-Pdk4 axis governs skeletal muscle mitochondrial energetics in chronic kidney disease. JCI Insight [Epub ahead of print]. https://doi.org/10.1172/jci.insight.178372 |
Fitzgerald 2024 J Cachexia Sarcopenia Muscle | 2024 | Fitzgerald LF, Lackey J, Moussa A, Shah SV, Castellanos AM, Khan S, Schonk M, Thome T, Salyers ZR, Jakkidi N, Kim K, Yang Q, Hepple RT, Ryan TE (2024) Chronic aryl hydrocarbon receptor activity impairs muscle mitochondrial function with tobacco smoking. https://doi.org/10.1002/jcsm.13439 |
Ryan 2022 Clin Transl Med | 2022 | Ryan TE, Kim K, Scali ST, Berceli SA, Thome T, Salyers ZR, O'Malley KA, Green TD, Karnekar R, Fisher-Wellman KH, Yamaguchi DJ, McClung JM (2022) Interventional- and amputation-stage muscle proteomes in the chronically threatened ischemic limb. https://doi.org/10.1002/ctm2.658 |
Salyers 2022 JVS Vasc Sci | 2022 | Salyers ZR, Mariani V, Balestrieri N, Kumar RA, Vugman NA, Thome T, Villani KR, Berceli SA, Scali ST, Vasilakos G, Ryan TE (2022) S100A8 and S100A9 are elevated in chronically threatened ischemic limb muscle and induce ischemic mitochondrial pathology in mice. https://doi.org/10.1016/j.jvssci.2022.03.003 |
Hahn 2021 Cell Physiol Biochem | 2021 | Hahn D, Kumar RA, Muscato DR, Ryan TE, SchrΓΆder K, Ferreira LF (2021) Nox4 knockout does not prevent diaphragm atrophy, contractile dysfunction, or mitochondrial maladaptation in the early phase post-myocardial infarction in mice. Cell Physiol Biochem 55:489-504. |
Terwilliger 2021 Vasc Med | 2021 | Terwilliger ZS, Ryan TE, Goldberg EJ, Schmidt CA, Yamaguchi DJ, Karnekar R, Brophy P, Green TD, Zeczycki TN, Mac Gabhann F, Annex BH, McClung JM (2021) Racial differences in the limb skeletal muscle transcriptional programs of patients with critical limb ischemia. Vasc Med 26:247-58. |
Thome 2020 JCI Insight | 2020 | Thome T, Kumar RA, Burke SK, Khattri RB, Salyers ZR, Kelley RC, Coleman MD, Christou DD, Hepple RT, Scali ST, Ferreira LF, Ryan TE (2020) Impaired muscle mitochondrial energetics is associated with uremic metabolite accumulation in chronic kidney disease. JCI Insight 6:e139826. |
Berru 2019 Sci Rep | 2019 | Berru FN, Gray SE, Thome T, Kumar RA, Salyers ZR, Coleman M, Dennis Le, O'Malley K, Ferreira LF, Berceli SA, Scali ST, Ryan TE (2019) Chronic kidney disease exacerbates ischemic limb myopathy in mice via altered mitochondrial energetics. Sci Rep 9:15547. |
Thome 2019 Am J Physiol Cell Physiol | 2019 | Thome T, Salyers ZR, Kumar RA, Hahn D, Berru FN, Ferreira LF, Scali ST, Ryan TE (2019) Uremic metabolites impair skeletal muscle mitochondrial energetics through disruption of the electron transport system and matrix dehydrogenase activity. Am J Physiol Cell Physiol 317:C701-13. |
Heden 2019 Sci Adv | 2019 | Heden TD, Johnson JM, Ferrara PJ, Eshima H, Verkerke ARP, Wentzler EJ, Siripoksup P, Narowski TM, Coleman CB, Lin CT, Ryan TE, Reidy PT, de Castro BrΓ‘s LE, Karner CM, Burant CF, Maschek JA, Cox JE, Mashek DG, Kardon G, Boudina S, Zeczycki TN, Rutter J, Shaikh SR, Vance JE, Drummond MJ, Neufer PD, Funai K (2019) Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity. Sci Adv 5:eaax8352. |
Powers 2019 Neurourol Urodyn | 2019 | Powers SA, Ryan TE, Pak ES, Fraser MO, McClung JM, Hannan JL (2019) Chronic high-fat diet decreased detrusor mitochondrial respiration and increased nerve-mediated contractions. Neurourol Urodyn 38:1524-32. |
Ryan 2018 JCI Insight | 2018 | Ryan TE, Yamaguchi DJ, Schmidt CA, Zeczycki TN, Shaikh SR, Brophy P, Green TD, Tarpey MD, Karnekar R, Goldberg EJ, Sparagna GC, Torres MJ, Annex BH, Neufer PD, Spangenburg EE, McClung JM (2018) Extensive skeletal muscle cell mitochondriopathy distinguishes critical limb ischemia patients from claudicants. JCI Insight 3:123235. |
Tarpey 2018 Skelet Muscle | 2018 | Tarpey MD, Amorese AJ, Balestrieri NP, Ryan TE, Schmidt CA, McClung JM, Spangenburg EE (2018) Characterization and utilization of the flexor digitorum brevis for assessing skeletal muscle function. Skelet Muscle 8:14. |
Torres 2018 Cell Metab | 2018 | Torres MJ, Kew KA, Ryan TE, Pennington ER, Lin CT, Buddo KA, Fix AM, Smith CA, Gilliam LA, Karvinen S, Lowe DA, Spangenburg EE, Zeczycki TN, Shaikh SR, Neufer PD (2018) 17Ξ²-estradiol directly lowers mitochondrial membrane microviscosity and improves bioenergetic function in skeletal muscle. Cell Metab 27:167-79. https://doi.org/10.1016/j.cmet.2017.10.003 |
Schmidt 2017 J Vasc Surg | 2017 | Schmidt CA, Ryan TE, Lin CT, Inigo MM, Green TD, Brault JJ, Spangenburg EE, McClung JM (2017) Diminished force production and mitochondrial respiratory deficits are strain-dependent myopathies of subacute limb ischemia. J Vasc Surg 65:1504-1514. |
Lark 2016 Am J Physiol Cell Physiol | 2016 | Lark DS, Torres MJ, Lin CT, Ryan TE, Anderson EJ, Neufer PD (2016) Direct real-time quantification of mitochondrial oxidative phosphorylation efficiency in permeabilized skeletal muscle myofibers. Am J Physiol Cell Physiol 311:C239-45. |
Gilliam 2016 Am J Physiol Endocrinol Metab | 2016 | Gilliam LA, Lark DS, Reese LR, Torres MJ, Ryan TE, Lin CT, Cathey BL, Neufer PD (2016) Targeted overexpression of mitochondrial catalase protects against cancer chemotherapy-induced skeletal muscle dysfunction. Am J Physiol Endocrinol Metab 311:E293-301. |
Ryan 2016 Diabetes | 2016 | Ryan TE, Schmidt CA, Green TD, Spangenburg EE, Neufer PD, McClung JM (2016) Targeted expression of catalase to mitochondria protects against ischemic myopathy in high fat fed mice. Diabetes 65:2553-68. |
Ryan 2016 J Mol Cell Cardiol | 2016 | Ryan TE, Schmidt CA, Alleman RJ, Tsang AM, Green TD, Neufer PD, Brown DA, McClung JM (2016) Mitochondrial therapy improves limb perfusion and myopathy following hindlimb ischemia. J Mol Cell Cardiol 97:191-6. |
Morad 2016 J Lipid Res | 2016 | Morad SA, Ryan TE, Neufer PD, Zeczycki TN, Davis TS, MacDougall MR, Fox TE, Tan SF, Feith DJ, Loughran TP Jr, Kester M, Claxton DF, Barth BM, Deering TG, Cabot MC (2016) Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia. J Lipid Res 57:1231-42. |
Alleman 2016 Am J Physiol Heart Circ Physiol | 2016 | Alleman RJ, Tsang AM, Ryan TE, Patteson DJ, McClung JM, Spangenburg EE, Shaikh SR, Neufer PD, Brown DA (2016) Exercise-induced protection against reperfusion arrhythmia involves stabilization of mitochondrial energetics. Am J Physiol Heart Circ Physiol 310:H1360-70. |
Lark 2015 Front Physiol | 2015 | Lark DS, Reese LR, Ryan TE, Torres MJ, Smith CD, Lin CT, Neufer PD (2015) Protein kinase A governs oxidative phosphorylation kinetics and oxidant emitting potential at complex I. https://doi.org/10.3389/fphys.2015.00332 |
Ryan 2014 J Physiol | 2014 | Ryan TE, Brophy P, Lin CT, Hickner RC, Neufer PD (2014) Assessment of in vivo skeletal muscle mitochondrial respiratory capacity in humans by near-infrared spectroscopy: a comparison with in situ measurements. J Physiol 592:3231-41. |
Abstracts
Published | Reference | |
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Neufer 2016 Abstract MitoFit Science Camp 2016 | 2016 | Direct real-time quantification of mitochondrial oxidative phosphorylation efficiency in permeabilized skeletal muscle myofibers. |
Terence 2015 Abstract MiPschool Greenville 2015 | 2015 | Mitochondrial dysfunction is a genetic component of ischemic tissue pathology and occurs independent of differential blood flow in the murine limb. |
Schmidt 2015 Abstract MiPschool Greenville 2015 | 2015 | High-fat diet induced mitochondrial dysfunction exacerbates limb pathology in genetically ischemia protected mice. |
Neufer 2014 Abstract MiP2014 | 2014 | Assessing ATP production and oxygen consumption simultaneously in permeabilized fibers: ATP/O. |