Rouet 2017 US Patent

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Rouet P, Smih F (2017) ApoO for use in method for treating cancer and various pathophysiological situations. US Patent US20170035842 A1.

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Rouet P, Smih F (2017) US Patent

Abstract: The invention relates to a compound for use for inducing apoptosis in a cancerous cell, wherein said compound is selected from the group consisting of ApoO, a variant or a fragment thereof, their mixtures, and a vector encoding for said ApoO, variant or fragment thereof. The invention further relates to a compound for use for treating a pathophysiological situation, wherein said compound is an inhibitor of the ApoO activity or of the ApoO gene expression.

Bioblast editor: Kandolf G

Labels: MiParea: Respiration  Pathology: Cancer, Diabetes, Obesity 

Organism: Human, Mouse  Tissue;cell: Heart, Liver  Preparation: Isolated mitochondria 

Coupling state: LEAK, ET  Pathway: ROX  HRR: Oxygraph-2k