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O2k-Publications: Topics
- Mitochondria and Cell Research - the Oroboros Ecosystem
Mitochondrial physiology: MiP areas
# O2k-Publications MitoPedia: Comment O2k Total 1 mt-Medicine (356 entries) 356 499 2 Exercise physiology;nutrition;life style 695 969 3 Comparative MiP;environmental MiP 308 454 4 Pharmacology;toxicology 775 928 5 mt-Biogenesis;mt-density 243 325 6 Genetic knockout;overexpression 575 641 7 Instruments;methods 251 384
Pathological states
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Aging;senescence 248 383 2 Alzheimer's 65 89 3 Autism 6 10 4 Cancer 323 431 5 Cardiovascular 177 246 6 COPD 9 12 7 Diabetes 330 432 8 Inherited 61 93 9 Infectious 44 61 10 Myopathy 60 71 11 Neurodegenerative 155 216 12 Obesity 226 368 13 Parkinson's 58 93 14 Sepsis 69 79 15 Other 250 321
Stress conditions
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Cell death White, brown, beige fat tissue 92 152 2 Cryopreservation 38 61 3 Hypoxia 92 184 4 Ischemia-reperfusion 306 410 5 Oxidative stress;RONS 551 778 6 Permeability transition 69 90 7 Temperature: hypothermia; hyperthermia 90 110
Organisms
- Mammals
- Model organisms
# O2k-Publications MitoPedia: Comment O2k Total 1 Chicken (» Birds) 4 6 2 Zebrafish (» Fishes) 11 16 3 Drosophila (» Hexapods) 57 74 4 Caenorhabditis elegans (» Nematodes) 22 30 5 Artemia (» Crustaceans) 11 18 6 Saccharomyces cerevisiae (» Fungi) 59 83 7 Comparative MiP 308 454
- Non-mammals
# O2k-Publications MitoPedia: Comment O2k Total 1 Birds (» Chicken) 11 22 2 Reptiles turtles, lizards, snakes, crocodiles, alligators 12 17 3 Amphibians frogs, toads, salamanders 10 15 4 Fishes bony fishes, carilaginous fishes (sharks, rays, skates) and jawless fishes (hagfish, lampreys); » Zebrafish 106 141 5 Hexapods insects, springtails; » Drosophila 32 41 6 Crustaceans crabs, shrimp, barnacles, etc.; » Artemia 19 39 7 Annelids polychaetes, e.g. lugworm Arenicola marina, oligochaetes, leeches 3 20 8 Molluscs gastropods, cephalopods, bivalves 22 39 9 Nematodes » Caenorhabditis elegans 5 11 10 Other invertebrates urocordates (e.g. ascidians, sea squirts); cephalochordates (amphioxus, lancelets); echinoderms; chelicerates (e.g. spiders, scorpions, horseshoe crabs); myriapods (millipedes, centipedes); gastrotrichs; rotifers; ctenophores; nemerteans; tardigrades; platyhelminthes; cnidaria; porifera; ... 11 18 11 Fungi yeast, molds, mushrooms, etc.; » Saccharomyces cerevisiae 50 61 12 Plants 31 59 13 Protists amoebas, ciliates, trypanosomes, dinoflagellates, diatoms, green algae, etc. 36 51 14 Eubacteria true bacteria, cyanobacteria, spirochetes 23 42 15 Archaea archaebacteria 0 7
Tissues and cells
- Tissues - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Fat White, brown, beige fat tissue 163 227 2 Genital 87 118 3 Heart 664 863 4 Kidney 132 164 5 Liver 590 766 6 Lung;Gill 53 72 7 Nervous system 558 674 8 Skeletal muscle 1005 1249
- Cell types - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Blood cells 230 285 2 Endothelial;epithelial;mesothelial cell 236 270 3 Fibroblast 192 251 4 Islet cell;pancreas;thymus 48 60 5 Leukemia 22 25 6 Lymphocyte 54 71 7 Platelets 110 128 8 Stem cells 35 47
- Cell lines - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 CHO 13 15 2 HEK 84 104 3 HeLa 35 52 4 Neuroblastoma 36 41 5 HUVEC 19 22 6 Macrophage-derived cell lines 25 34 7 Other cells and cell lines 281 323
Preparations
# O2k-Publications MitoPedia: Comment O2k Total 1 Living organism 48 238 2 Intact organ 22 36 3 Living cells 1050 1180 4 Permeabilized cells 639 672 5 Permeabilized tissue 1013 1099 6 Homogenate 328 366 7 Isolated mitochondria 1161 1452 8 SMP Submitochondrial particles 10 28 9 Chloroplasts 2 10 10 Enzyme 39 74 11 Oxidase and biochemical oxidation 38 48
Enzymes
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Adenine nucleotide translocase ANT 21 25 2 Complex I CI 447 535 3 Complex II;succinate dehydrogenase CII 393 465 4 Complex III CIII 297 346 5 Complex IV;cytochrome c oxidase CIV 402 473 6 Complex V;ATP synthase CV 218 258 7 mt-Inner membrane transporter 31 43 8 Marker enzyme 57 80 9 Supercomplex 44 60 10 TCA cycle and matrix dehydrogenases Tricarboxylic acid cycle 80 105 11 Uncoupling protein 59 64
Regulation
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 ADP ADP kinetics 147 197 2 ATP production 75 112 3 Aerobic glycolysis 46 90 4 Amino acid 9 19 5 Calcium 97 164 6 Coupling efficiency;uncoupling 80 145 7 Cyt c Cytochrome c 40 53 8 Fatty acid FA substrate kinetics 120 144 9 Flux control 52 83 10 Inhibitor Inhibitor kinetics 127 158 11 Ion;substrate transport 56 103 12 mt-Membrane potential Mitochondrial membrane potential
- Bioblast links: Force and membrane potential - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
.::: Fundamental relationships
- mt-Membrane potential and protonmotive force
- O2k-Potentiometry
- » O2k-Catalogue: O2k-TPP+ ISE-Module
- » O2k-Manual: MiPNet15.03 O2k-MultiSensor-ISE
- » TPP - O2k-Procedures: Tetraphenylphosphonium
- » Specifications: MiPNet15.08 TPP electrode
- » Poster
- » Unspecific binding of TPP+
- » TPP+ inhibitory effect
- O2k-Potentiometry
- O2k-Fluorometry
- » O2k-Catalogue: O2k-FluoRespirometer
- » O2k-Manual: MiPNet22.11 O2k-FluoRespirometer manual
- » Safranin - O2k-Procedures: MiPNet20.13 Safranin mt-membranepotential / Safranin
- » TMRM - O2k-Procedures: TMRM
- O2k-Fluorometry
- O2k-Publications
104 158 13 Oxygen kinetics 101 139 14 Q-junction effect 13 55 15 Redox state 50 85 16 Substrate Fuel substrate kinetics 179 231 17 Temperature Temperature dependence 67 92 18 Threshold;excess capacity 27 30 19 Uncoupler Uncoupler kinetics 53 68
Coupling-control
# O2k-Publications MitoPedia: Coupling-control states Comment O2k Total 1 P 
OXPHOS capacity
Oxidative phosphorylation capacity, saturating [ADP] 2584 2795 2 R 
ROUTINE respiration
Physiological state, living cells 800 880 3 E 
ET capacity
Maximal noncoupled respiration 1835 1933 4 L 
LEAK respiration
Resting state, non-phosphorylating respiration 2292 2436
Pathway control
# O2k-Publications MitoPedia: Electron-transfer-pathway states Comment O2k Total 1 F F-pathway control state Fatty acid oxidation, level 5 542 641 2 N N-pathway control state NADH-linked, level 4 2202 2341 3 S S-pathway control state Succinate-linked, level 3 1499 1581 4 Gp Gp-pathway control state Glycerophosphate-linked, level 3 140 162 5 DQ Duorquinol-linked, level 2 23 27 6 CIV Complex IV single step Ascorbate & TMPD, level 1 618 645 7 NS NS-pathway control state Convergent CI- and CII-linked electron flow to the Q-junction 1382 1435 8 Other 129 145 9 ROX 
Residual oxygen consumption
includes non-mitochondrial respiration 1314 1364
MiPMap combinations - examples
- Examples for specific combinations
# O2k-Publications MitoPedia: Comment O2k Total 1 O2k-Publications: Human skeletal muscle 1005 1249 2 O2k-Publications: Human heart 664 863 3 O2k-Publications: Skeletal muscle - human vs mouse 36 45
- Browse data
O2k-Manuals and protocols and specific instrumental applications
# O2k-Publications MitoPedia: Comment O2k Total 1 Twin-Flow respirometry 0 21 2 Separate DatLab applications 29 35