From Bioblast
O2k-Publications: Topics
- Mitochondria and Cell Research - the Oroboros Ecosystem
Mitochondrial physiology: MiP areas
# O2k-Publications MitoPedia: Comment O2k Total 1 mt-Medicine (357 entries) 357 500 2 Exercise physiology;nutrition;life style 713 989 3 Comparative MiP;environmental MiP 313 459 4 Pharmacology;toxicology 802 958 5 mt-Biogenesis;mt-density 245 327 6 Genetic knockout;overexpression 608 674 7 Instruments;methods 263 398
Pathological states
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Aging;senescence 256 391 2 Alzheimer's 68 92 3 Autism 7 11 4 Cancer 333 443 5 Cardiovascular 190 259 6 COPD 9 12 7 Diabetes 339 441 8 Inherited 61 93 9 Infectious 47 65 10 Myopathy 65 76 11 Neurodegenerative 159 220 12 Obesity 240 382 13 Parkinson's 62 98 14 Sepsis 70 80 15 Other 267 338
Stress conditions
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Cell death White, brown, beige fat tissue 92 154 2 Cryopreservation 38 61 3 Hypoxia 101 195 4 Ischemia-reperfusion 316 420 5 Oxidative stress;RONS 560 789 6 Permeability transition 71 93 7 Temperature: hypothermia; hyperthermia 90 110
Organisms
- Mammals
- Model organisms
# O2k-Publications MitoPedia: Comment O2k Total 1 Chicken (» Birds) 5 7 2 Zebrafish (» Fishes) 14 20 3 Drosophila (» Hexapods) 61 78 4 Caenorhabditis elegans (» Nematodes) 23 31 5 Artemia (» Crustaceans) 11 18 6 Saccharomyces cerevisiae (» Fungi) 60 84 7 Comparative MiP 313 459
- Non-mammals
# O2k-Publications MitoPedia: Comment O2k Total 1 Birds (» Chicken) 13 24 2 Reptiles turtles, lizards, snakes, crocodiles, alligators 13 18 3 Amphibians frogs, toads, salamanders 10 15 4 Fishes bony fishes, carilaginous fishes (sharks, rays, skates) and jawless fishes (hagfish, lampreys); » Zebrafish 109 145 5 Hexapods insects, springtails; » Drosophila 32 41 6 Crustaceans crabs, shrimp, barnacles, etc.; » Artemia 19 39 7 Annelids polychaetes, e.g. lugworm Arenicola marina, oligochaetes, leeches 3 20 8 Molluscs gastropods, cephalopods, bivalves 24 41 9 Nematodes » Caenorhabditis elegans 5 11 10 Other invertebrates urocordates (e.g. ascidians, sea squirts); cephalochordates (amphioxus, lancelets); echinoderms; chelicerates (e.g. spiders, scorpions, horseshoe crabs); myriapods (millipedes, centipedes); gastrotrichs; rotifers; ctenophores; nemerteans; tardigrades; platyhelminthes; cnidaria; porifera; ... 11 18 11 Fungi yeast, molds, mushrooms, etc.; » Saccharomyces cerevisiae 51 62 12 Plants 32 64 13 Protists amoebas, ciliates, trypanosomes, dinoflagellates, diatoms, green algae, etc. 40 56 14 Eubacteria true bacteria, cyanobacteria, spirochetes 24 43 15 Archaea archaebacteria 0 7
Tissues and cells
- Tissues - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Fat White, brown, beige fat tissue 177 241 2 Genital 91 122 3 Heart 687 886 4 Kidney 136 168 5 Liver 614 791 6 Lung;Gill 55 75 7 Nervous system 574 691 8 Skeletal muscle 1038 1284
- Cell types - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Blood cells 235 290 2 Endothelial;epithelial;mesothelial cell 244 279 3 Fibroblast 197 256 4 Islet cell;pancreas;thymus 51 63 5 Leukemia 22 25 6 Lymphocyte 55 73 7 Platelets 113 131 8 Stem cells 36 48
- Cell lines - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 CHO 13 15 2 HEK 89 109 3 HeLa 36 53 4 Neuroblastoma 42 48 5 HUVEC 19 22 6 Macrophage-derived cell lines 26 35 7 Other cells and cell lines 289 333
Preparations
# O2k-Publications MitoPedia: Comment O2k Total 1 Living organism 51 242 2 Intact organ 22 36 3 Living cells 1089 1221 4 Permeabilized cells 674 707 5 Permeabilized tissue 1048 1135 6 Homogenate 349 387 7 Isolated mitochondria 1201 1492 8 SMP Submitochondrial particles 10 28 9 Chloroplasts 2 10 10 Enzyme 39 74 11 Oxidase and biochemical oxidation 38 48
Enzymes
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Adenine nucleotide translocase ANT 21 26 2 Complex I CI 452 541 3 Complex II;succinate dehydrogenase CII 395 467 4 Complex III CIII 298 348 5 Complex IV;cytochrome c oxidase CIV 402 473 6 Complex V;ATP synthase CV 219 259 7 mt-Inner membrane transporter 31 43 8 Marker enzyme 57 80 9 Supercomplex 45 61 10 TCA cycle and matrix dehydrogenases Tricarboxylic acid cycle 81 106 11 Uncoupling protein 59 64
Regulation
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 ADP ADP kinetics 147 198 2 ATP production 78 117 3 Aerobic glycolysis 48 92 4 Amino acid 9 19 5 Calcium 100 169 6 Coupling efficiency;uncoupling 81 147 7 Cyt c Cytochrome c 39 52 8 Fatty acid FA substrate kinetics 120 145 9 Flux control 53 85 10 Inhibitor Inhibitor kinetics 127 159 11 Ion;substrate transport 60 107 12 mt-Membrane potential Mitochondrial membrane potential
- Bioblast links: Force and membrane potential - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
- Fundamental relationships
- mt-Membrane potential and protonmotive force
- O2k-Potentiometry
- » O2k-Catalogue: O2k-TPP+ ISE-Module
- » O2k-Manual: MiPNet15.03 O2k-MultiSensor-ISE
- » TPP - O2k-Procedures: Tetraphenylphosphonium
- » Specifications: MiPNet15.08 TPP electrode
- » Poster
- » Unspecific binding of TPP+
- » TPP+ inhibitory effect
- O2k-Potentiometry
- O2k-Fluorometry
- » O2k-Catalogue: O2k-FluoRespirometer
- » O2k-Manual: MiPNet22.11 O2k-FluoRespirometer manual
- » Safranin - O2k-Procedures: MiPNet20.13 Safranin mt-membranepotential / Safranin
- » TMRM - O2k-Procedures: TMRM
- O2k-Fluorometry
- O2k-Publications
106 161 13 Oxygen kinetics 103 141 14 Q-junction effect 13 55 15 Redox state 50 85 16 Substrate Fuel substrate kinetics 179 231 17 Temperature Temperature dependence 70 95 18 Threshold;excess capacity 27 30 19 Uncoupler Uncoupler kinetics 54 69
Coupling-control
# O2k-Publications MitoPedia: Coupling-control states Comment O2k Total 1 P 
OXPHOS capacity
Oxidative phosphorylation capacity, saturating [ADP] 2703 2915 2 R 
ROUTINE respiration
Physiological state, living cells 829 911 3 E 
ET capacity
Maximal noncoupled respiration 1923 2021 4 L 
LEAK respiration
Resting state, non-phosphorylating respiration 2424 2569
Pathway control
# O2k-Publications MitoPedia: Electron-transfer-pathway states Comment O2k Total 1 F F-pathway control state Fatty acid oxidation, level 5 565 663 2 N N-pathway control state NADH-linked, level 4 2313 2452 3 S S-pathway control state Succinate-linked, level 3 1571 1652 4 Gp Gp-pathway control state Glycerophosphate-linked, level 3 148 170 5 DQ Duorquinol-linked, level 2 23 27 6 CIV Complex IV single step Ascorbate & TMPD, level 1 655 682 7 NS NS-pathway control state Convergent CI- and CII-linked electron flow to the Q-junction 1461 1513 8 Other 130 146 9 ROX 
Residual oxygen consumption
includes non-mitochondrial respiration 1407 1457
MiPMap combinations - examples
- Examples for specific combinations
# O2k-Publications MitoPedia: Comment O2k Total 1 O2k-Publications: Human skeletal muscle 1038 1284 2 O2k-Publications: Human heart 687 886 3 O2k-Publications: Skeletal muscle - human vs mouse 37 46
- Browse data
O2k-Manuals and protocols and specific instrumental applications
# O2k-Publications MitoPedia: Comment O2k Total 1 Twin-Flow respirometry 0 21 2 Separate DatLab applications 29 35
