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O2k-Publications: Topics
- Mitochondria and Cell Research - the Oroboros Ecosystem
Contents
- 1 Mitochondrial physiology: MiP areas
- 2 Pathological states
- 3 Stress conditions
- 4 Organisms
- 5 Tissues and cells
- 6 Preparations
- 7 Enzymes
- 8 Regulation
- 9 Coupling-control states
- 10 Pathway control states
- 11 MiPMap combinations - examples
- 12 O2k-Manuals and protocols and specific instrumental applications
Mitochondrial physiology: MiP areas
# O2k-Publications MitoPedia: Comment O2k Total 1 mt-Medicine (354 entries) 354 484 2 Exercise physiology;nutrition;life style 642 888 3 Comparative MiP;environmental MiP 297 434 4 Pharmacology;toxicology 695 830 5 mt-Biogenesis;mt-density 233 307 6 Genetic knockout;overexpression 521 579 7 Instruments;methods 217 322
Pathological states
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Aging;senescence 235 361 2 Alzheimer's 61 82 3 Autism 3 7 4 Cancer 304 402 5 Cardiovascular 155 221 6 COPD 8 11 7 Diabetes 301 401 8 Inherited 60 81 9 Infectious 37 50 10 Myopathy 55 66 11 Neurodegenerative 147 202 12 Obesity 208 348 13 Parkinson's 52 83 14 Sepsis 61 71 15 Other 229 297
Stress conditions
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Cell death White, brown, beige fat tissue 89 146 2 Cryopreservation 34 57 3 Hypoxia 75 107 4 Ischemia-reperfusion 295 397 5 Oxidative stress;RONS 533 739 6 Permeability transition 66 87 7 Temperature: hypothermia; hyperthermia 88 105
Organisms
- Mammals
- Model organisms
# O2k-Publications MitoPedia: Comment O2k Total 1 Chicken (» Birds) 4 5 2 Zebrafish (» Fishes) 11 16 3 Drosophila (» Hexapods) 51 66 4 Caenorhabditis elegans (» Nematodes) 19 27 5 Artemia (» Crustaceans) 11 18 6 Saccharomyces cerevisiae (» Fungi) 53 73 7 Comparative MiP 297 434
- Non-mammals
# O2k-Publications MitoPedia: Comment O2k Total 1 Birds (» Chicken) 11 21 2 Reptiles turtles, lizards, snakes, crocodiles, alligators 10 14 3 Amphibians frogs, toads, salamanders 10 14 4 Fishes bony fishes, carilaginous fishes (sharks, rays, skates) and jawless fishes (hagfish, lampreys); » Zebrafish 100 130 5 Hexapods insects, springtails; » Drosophila 31 40 6 Crustaceans crabs, shrimp, barnacles, etc.; » Artemia 19 37 7 Annelids polychaetes, e.g. lugworm Arenicola marina, oligochaetes, leeches 3 16 8 Molluscs gastropods, cephalopods, bivalves 19 29 9 Nematodes » Caenorhabditis elegans 4 9 10 Other invertebrates urocordates (e.g. ascidians, sea squirts); cephalochordates (amphioxus, lancelets); echinoderms; chelicerates (e.g. spiders, scorpions, horseshoe crabs); myriapods (millipedes, centipedes); gastrotrichs; rotifers; ctenophores; nemerteans; tardigrades; platyhelminthes; cnidaria; porifera; ... 11 15 11 Fungi yeast, molds, mushrooms, etc.; » Saccharomyces cerevisiae 48 59 12 Plants 27 47 13 Protists amoebas, ciliates, trypanosomes, dinoflagellates, diatoms, green algae, etc. 31 43 14 Eubacteria true bacteria, cyanobacteria, spirochetes 23 39 15 Archaea archaebacteria 0 6
Tissues and cells
- Tissues - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Fat White, brown, beige fat tissue 152 213 2 Genital 81 110 3 Heart 618 799 4 Kidney 124 152 5 Liver 550 708 6 Lung;Gill 49 64 7 Nervous system 513 613 8 Skeletal muscle 933 1148
- Cell types - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Blood cells 220 270 2 Endothelial;epithelial;mesothelial cell 223 253 3 Fibroblast 171 217 4 Islet cell;pancreas;thymus 45 55 5 Leukemia 22 25 6 Lymphocyte 48 62 7 Platelets 102 120 8 Stem cells 31 41
- Cell lines - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 CHO 13 13 2 HEK 73 91 3 HeLa 30 43 4 Neuroblastoma 32 35 5 HUVEC 19 22 6 Macrophage-derived cell lines 24 33 7 Other cells and cell lines 271 308
Preparations
# O2k-Publications MitoPedia: Comment O2k Total 1 Living organism 43 213 2 Intact organ 21 34 3 Living cells 950 1049 4 Permeabilized cells 562 593 5 Permeabilized tissue 944 1028 6 Homogenate 299 334 7 Isolated mitochondria 1087 1356 8 SMP Submitochondrial particles 9 21 9 Chloroplasts 1 9 10 Enzyme 39 68 11 Oxidase and biochemical oxidation 38 48
Enzymes
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Adenine nucleotide translocase ANT 20 24 2 Complex I CI 429 513 3 Complex II;succinate dehydrogenase CII 379 448 4 Complex III CIII 289 333 5 Complex IV;cytochrome c oxidase CIV 390 457 6 Complex V;ATP synthase CV 211 249 7 mt-Inner membrane transporter 31 43 8 Marker enzyme 50 71 9 Supercomplex 41 54 10 TCA cycle and matrix dehydrogenases Tricarboxylic acid cycle 75 95 11 Uncoupling protein 57 62
Regulation
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 ADP ADP kinetics 145 190 2 ATP production 71 104 3 Aerobic glycolysis 41 76 4 Amino acid 9 18 5 Calcium 88 133 6 Coupling efficiency;uncoupling 71 132 7 Cyt c Cytochrome c 38 47 8 Fatty acid FA substrate kinetics 116 140 9 Flux control 46 73 10 Inhibitor Inhibitor kinetics 127 155 11 Ion;substrate transport 54 94 12 mt-Membrane potential Mitochondrial membrane potential
- Bioblast links: Force and membrane potential - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
.::: Fundamental relationships
- mt-Membrane potential and protonmotive force
- O2k-Potentiometry
- » O2k-Catalogue: O2k-TPP+ ISE-Module
- » O2k-Manual: MiPNet15.03 O2k-MultiSensor-ISE
- » TPP - O2k-Procedures: Tetraphenylphosphonium
- » Specifications: MiPNet15.08 TPP electrode
- » Poster
- » Unspecific binding of TPP+
- » TPP+ inhibitory effect
- O2k-Potentiometry
- O2k-Fluorometry
- » O2k-Catalogue: O2k-FluoRespirometer
- » O2k-Manual: MiPNet22.11 O2k-FluoRespirometer manual
- » Safranin - O2k-Procedures: MiPNet20.13 Safranin mt-membranepotential / Safranin
- » TMRM - O2k-Procedures: TMRM
- O2k-Fluorometry
- O2k-Publications
97 147 13 Oxygen kinetics 96 127 14 Q-junction effect 6 7 15 Redox state 45 70 16 Substrate Fuel substrate kinetics 175 227 17 Temperature Temperature dependence 59 82 18 Threshold;excess capacity 27 30 19 Uncoupler Uncoupler kinetics 52 68
Coupling-control states
# O2k-Publications MitoPedia: Coupling-control states Comment O2k Total 1 P 
OXPHOS capacity
Oxidative phosphorylation capacity, saturating [ADP] 2356 2552 2 R 
ROUTINE respiration
Physiological state, living cells 717 776 3 E 
ET capacity
Maximal noncoupled respiration 1637 1721 4 L 
LEAK respiration
Resting state, non-phosphorylating respiration 2044 2172
Pathway control states
# O2k-Publications MitoPedia: Electron-transfer-pathway states Comment O2k Total 1 F F-pathway control state Fatty acid oxidation, level 5 490 584 2 N N-pathway control state NADH-linked, level 4 1993 2113 3 S S-pathway control state Succinate-linked, level 3 1333 1404 4 Gp Gp-pathway control state Glycerophosphate-linked, level 3 124 142 5 DQ Duorquinol-linked, level 2 17 21 6 CIV Complex IV single step Ascorbate & TMPD, level 1 562 588 7 NS NS-pathway control state Convergent CI- and CII-linked electron flow to the Q-junction 1240 1286 8 Other 123 139 9 ROX 
Residual oxygen consumption
includes non-mitochondrial respiration 1148 1190
MiPMap combinations - examples
- Examples for specific combinations
# O2k-Publications MitoPedia: Comment O2k Total 1 O2k-Publications: Human skeletal muscle 933 1148 2 O2k-Publications: Human heart 618 799 3 O2k-Publications: Skeletal muscle - human vs mouse 36 44
- Browse data
O2k-Manuals and protocols and specific instrumental applications
# O2k-Publications MitoPedia: Comment O2k Total 1 Twin-Flow respirometry 0 21 2 Separate DatLab applications 27 33
