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O2k-Publications: Topics
- Mitochondria and Cell Research - the Oroboros Ecosystem
Contents
- 1 Mitochondrial physiology: MiP areas
- 2 Pathological states
- 3 Stress conditions
- 4 Organisms
- 5 Tissues and cells
- 6 Preparations
- 7 Enzymes
- 8 Regulation
- 9 Coupling control states
- 10 Pathway control states
- 11 MiPMap combinations - examples
- 12 O2k-Manuals and protocols and specific instrumental applications
Mitochondrial physiology: MiP areas
# O2k-Publications MitoPedia: Comment O2k Total 1 mt-Medicine (354 entries) 354 483 2 Exercise physiology;nutrition;life style 622 868 3 Comparative MiP;environmental MiP 290 427 4 Pharmacology;toxicology 663 797 5 mt-Biogenesis;mt-density 231 305 6 Genetic knockout;overexpression 501 559 7 Instruments;methods 208 311
Pathological states
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Aging;senescence 226 352 2 Alzheimer's 60 81 3 Autism 3 7 4 Cancer 293 391 5 Cardiovascular 147 213 6 COPD 8 11 7 Diabetes 287 387 8 Inherited 60 81 9 Infectious 34 46 10 Myopathy 54 65 11 Neurodegenerative 145 200 12 Obesity 190 330 13 Parkinson's 52 83 14 Sepsis 61 71 15 Other 218 286
Stress conditions
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Cell death White, brown, beige fat tissue 85 142 2 Cryopreservation 33 56 3 Hypoxia 70 102 4 Ischemia-reperfusion 289 391 5 Oxidative stress;RONS 519 725 6 Permeability transition 62 83 7 Temperature: hypothermia; hyperthermia 85 102
Organisms
- Mammals
- Model organisms
# O2k-Publications MitoPedia: Comment O2k Total 1 Chicken (» Birds) 4 5 2 Zebrafish (» Fishes) 11 16 3 Drosophila (» Hexapods) 50 65 4 Caenorhabditis elegans (» Nematodes) 18 26 5 Artemia (» Crustaceans) 11 18 6 Saccharomyces cerevisiae (» Fungi) 52 72 7 Comparative MiP 290 427
- Non-mammals
# O2k-Publications MitoPedia: Comment O2k Total 1 Birds (» Chicken) 11 21 2 Reptiles turtles, lizards, snakes, crocodiles, alligators 10 14 3 Amphibians frogs, toads, salamanders 9 13 4 Fishes bony fishes, carilaginous fishes (sharks, rays, skates) and jawless fishes (hagfish, lampreys); » Zebrafish 98 127 5 Hexapods insects, springtails; » Drosophila 30 39 6 Crustaceans crabs, shrimp, barnacles, etc.; » Artemia 19 37 7 Annelids polychaetes, e.g. lugworm Arenicola marina, oligochaetes, leeches 3 16 8 Molluscs gastropods, cephalopods, bivalves 18 28 9 Nematodes » Caenorhabditis elegans 3 8 10 Other invertebrates urocordates (e.g. ascidians, sea squirts); cephalochordates (amphioxus, lancelets); echinoderms; chelicerates (e.g. spiders, scorpions, horseshoe crabs); myriapods (millipedes, centipedes); gastrotrichs; rotifers; ctenophores; nemerteans; tardigrades; platyhelminthes; cnidaria; porifera; ... 11 15 11 Fungi yeast, molds, mushrooms, etc.; » Saccharomyces cerevisiae 48 59 12 Plants 25 45 13 Protists amoebas, ciliates, trypanosomes, dinoflagellates, diatoms, green algae, etc. 28 40 14 Eubacteria true bacteria, cyanobacteria, spirochetes 23 39 15 Archaea archaebacteria 0 6
Tissues and cells
- Tissues - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Fat White, brown, beige fat tissue 149 210 2 Genital 79 108 3 Heart 598 779 4 Kidney 117 145 5 Liver 541 699 6 Lung;Gill 46 61 7 Nervous system 500 600 8 Skeletal muscle 901 1116
- Cell types - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Blood cells 211 261 2 Endothelial;epithelial;mesothelial cell 211 241 3 Fibroblast 168 214 4 Islet cell;pancreas;thymus 43 53 5 Leukemia 23 26 6 Lymphocyte 48 62 7 Platelets 101 119 8 Stem cells 30 40
- Cell lines - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 CHO 13 13 2 HEK 69 87 3 HeLa 29 42 4 Neuroblastoma 32 35 5 HUVEC 19 22 6 Macrophage-derived cell lines 23 32 7 Other cells and cell lines 266 303
Preparations
# O2k-Publications MitoPedia: Comment O2k Total 1 Living organism 40 207 2 Intact organ 21 34 3 Living cells 907 1005 4 Permeabilized cells 542 572 5 Permeabilized tissue 910 994 6 Homogenate 287 321 7 Isolated mitochondria 1059 1327 8 SMP Submitochondrial particles 9 21 9 Chloroplasts 1 9 10 Enzyme 39 67 11 Oxidase and biochemical oxidation 37 47
Enzymes
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Adenine nucleotide translocase ANT 20 24 2 Complex I CI 423 507 3 Complex II;succinate dehydrogenase CII 373 441 4 Complex III CIII 285 329 5 Complex IV;cytochrome c oxidase CIV 385 452 6 Complex V;ATP synthase CV 206 244 7 mt-Inner membrane transporter 31 43 8 Marker enzyme 50 71 9 Supercomplex 41 54 10 TCA cycle and matrix dehydrogenases Tricarboxylic acid cycle 75 95 11 Uncoupling protein 57 62
Regulation
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 ADP ADP kinetics 145 190 2 ATP production 70 103 3 Aerobic glycolysis 41 76 4 Amino acid 9 18 5 Calcium 86 131 6 Coupling efficiency;uncoupling 71 132 7 Cyt c Cytochrome c 37 46 8 Fatty acid FA substrate kinetics 116 140 9 Flux control 46 73 10 Inhibitor Inhibitor kinetics 128 156 11 Ion;substrate transport 51 91 12 mt-Membrane potential Mitochondrial membrane potential
- Bioblast links: Force and membrane potential - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
.::: Fundamental relationships
- mt-Membrane potential and protonmotive force
- O2k-Potentiometry
- » O2k-Catalogue: O2k-TPP+ ISE-Module
- » O2k-Manual: MiPNet15.03 O2k-MultiSensor-ISE
- » TPP - O2k-Procedures: Tetraphenylphosphonium
- » Specifications: MiPNet15.08 TPP electrode
- » Poster
- » Unspecific binding of TPP+
- » TPP+ inhibitory effect
- O2k-Potentiometry
- O2k-Fluorometry
- » O2k-Catalogue: O2k-FluoRespirometer
- » O2k-Manual: MiPNet22.11 O2k-FluoRespirometer manual
- » Safranin - O2k-Procedures: MiPNet20.13 Safranin mt-membranepotential / Safranin
- » TMRM - O2k-Procedures: TMRM
- O2k-Fluorometry
- O2k-Publications
94 144 13 Oxygen kinetics 95 126 14 Q-junction effect 6 7 15 Redox state 45 70 16 Substrate Fuel substrate kinetics 173 224 17 Temperature Temperature dependence 58 81 18 Threshold;excess capacity 27 30 19 Uncoupler Uncoupler kinetics 51 67
Coupling control states
# O2k-Publications MitoPedia: Coupling control states Comment O2k Total 1 P 
OXPHOS capacity
Oxidative phosphorylation capacity, saturating [ADP] 2268 2464 2 R 
ROUTINE respiration
Physiological state, living cells 682 741 3 E 
ET-capacity
Maximal noncoupled respiration 1564 1647 4 L 
LEAK respiration
Resting state, non-phosphorylating respiration 1937 2065
Pathway control states
# O2k-Publications MitoPedia: Electron transfer-pathway states Comment O2k Total 1 F F-pathway control state Fatty acid oxidation, level 5 467 561 2 N N-pathway control state NADH-linked, level 4 1906 2026 3 S S-pathway control state Succinate-linked, level 3 1280 1351 4 Gp Gp-pathway control state Glycerophosphate-linked, level 3 118 136 5 DQ Duorquinol-linked, level 2 17 21 6 CIV Complex IV single step Ascorbate & TMPD, level 1 542 568 7 NS NS-pathway control state Convergent CI- and CII-linked electron flow to the Q-junction 1181 1227 8 Other 123 139 9 ROX 
Residual oxygen consumption
includes non-mitochondrial respiration 1089 1131
MiPMap combinations - examples
- Examples for specific combinations
# O2k-Publications MitoPedia: Comment O2k Total 1 O2k-Publications: Human skeletal muscle 901 1116 2 O2k-Publications: Human heart 598 779 3 O2k-Publications: Skeletal muscle - human vs mouse 36 44
- Browse data
O2k-Manuals and protocols and specific instrumental applications
# O2k-Publications MitoPedia: Comment O2k Total 1 Twin-Flow respirometry 0 21 2 Separate DatLab applications 26 32
