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O2k-Publications: Topics
- Mitochondria and Cell Research - the Oroboros Ecosystem
Mitochondrial physiology: MiP areas
# O2k-Publications MitoPedia: Comment O2k Total 1 mt-Medicine (357 entries) 357 495 2 Exercise physiology;nutrition;life style 659 910 3 Comparative MiP;environmental MiP 301 440 4 Pharmacology;toxicology 751 890 5 mt-Biogenesis;mt-density 239 319 6 Genetic knockout;overexpression 553 612 7 Instruments;methods 229 342
Pathological states
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Aging;senescence 243 376 2 Alzheimer's 65 87 3 Autism 6 10 4 Cancer 317 419 5 Cardiovascular 171 238 6 COPD 8 11 7 Diabetes 316 418 8 Inherited 60 81 9 Infectious 39 52 10 Myopathy 58 69 11 Neurodegenerative 149 207 12 Obesity 221 363 13 Parkinson's 52 84 14 Sepsis 65 75 15 Other 239 308
Stress conditions
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Cell death White, brown, beige fat tissue 91 148 2 Cryopreservation 35 58 3 Hypoxia 78 113 4 Ischemia-reperfusion 301 404 5 Oxidative stress;RONS 544 756 6 Permeability transition 67 88 7 Temperature: hypothermia; hyperthermia 89 106
Organisms
- Mammals
- Model organisms
# O2k-Publications MitoPedia: Comment O2k Total 1 Chicken (» Birds) 4 5 2 Zebrafish (» Fishes) 11 16 3 Drosophila (» Hexapods) 55 72 4 Caenorhabditis elegans (» Nematodes) 21 29 5 Artemia (» Crustaceans) 11 18 6 Saccharomyces cerevisiae (» Fungi) 56 76 7 Comparative MiP 301 440
- Non-mammals
# O2k-Publications MitoPedia: Comment O2k Total 1 Birds (» Chicken) 11 21 2 Reptiles turtles, lizards, snakes, crocodiles, alligators 10 15 3 Amphibians frogs, toads, salamanders 10 15 4 Fishes bony fishes, carilaginous fishes (sharks, rays, skates) and jawless fishes (hagfish, lampreys); » Zebrafish 106 136 5 Hexapods insects, springtails; » Drosophila 31 40 6 Crustaceans crabs, shrimp, barnacles, etc.; » Artemia 19 37 7 Annelids polychaetes, e.g. lugworm Arenicola marina, oligochaetes, leeches 3 16 8 Molluscs gastropods, cephalopods, bivalves 21 31 9 Nematodes » Caenorhabditis elegans 5 10 10 Other invertebrates urocordates (e.g. ascidians, sea squirts); cephalochordates (amphioxus, lancelets); echinoderms; chelicerates (e.g. spiders, scorpions, horseshoe crabs); myriapods (millipedes, centipedes); gastrotrichs; rotifers; ctenophores; nemerteans; tardigrades; platyhelminthes; cnidaria; porifera; ... 11 15 11 Fungi yeast, molds, mushrooms, etc.; » Saccharomyces cerevisiae 50 61 12 Plants 29 53 13 Protists amoebas, ciliates, trypanosomes, dinoflagellates, diatoms, green algae, etc. 32 44 14 Eubacteria true bacteria, cyanobacteria, spirochetes 24 43 15 Archaea archaebacteria 0 6
Tissues and cells
- Tissues - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Fat White, brown, beige fat tissue 157 218 2 Genital 83 112 3 Heart 645 834 4 Kidney 128 157 5 Liver 573 736 6 Lung;Gill 53 68 7 Nervous system 538 640 8 Skeletal muscle 968 1189
- Cell types - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Blood cells 225 276 2 Endothelial;epithelial;mesothelial cell 230 261 3 Fibroblast 182 234 4 Islet cell;pancreas;thymus 45 57 5 Leukemia 22 25 6 Lymphocyte 52 66 7 Platelets 106 124 8 Stem cells 33 43
- Cell lines - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 CHO 13 13 2 HEK 75 93 3 HeLa 32 46 4 Neuroblastoma 36 39 5 HUVEC 19 22 6 Macrophage-derived cell lines 24 33 7 Other cells and cell lines 276 314
Preparations
# O2k-Publications MitoPedia: Comment O2k Total 1 Living organism 49 222 2 Intact organ 22 35 3 Living cells 1000 1109 4 Permeabilized cells 597 631 5 Permeabilized tissue 977 1063 6 Homogenate 312 349 7 Isolated mitochondria 1133 1412 8 SMP Submitochondrial particles 9 26 9 Chloroplasts 1 9 10 Enzyme 39 70 11 Oxidase and biochemical oxidation 38 48
Enzymes
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Adenine nucleotide translocase ANT 21 25 2 Complex I CI 439 525 3 Complex II;succinate dehydrogenase CII 386 458 4 Complex III CIII 294 341 5 Complex IV;cytochrome c oxidase CIV 398 468 6 Complex V;ATP synthase CV 214 254 7 mt-Inner membrane transporter 31 43 8 Marker enzyme 52 75 9 Supercomplex 43 59 10 TCA cycle and matrix dehydrogenases Tricarboxylic acid cycle 77 98 11 Uncoupling protein 59 64
Regulation
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 ADP ADP kinetics 146 192 2 ATP production 73 106 3 Aerobic glycolysis 41 77 4 Amino acid 9 18 5 Calcium 92 139 6 Coupling efficiency;uncoupling 75 139 7 Cyt c Cytochrome c 38 50 8 Fatty acid FA substrate kinetics 118 142 9 Flux control 48 79 10 Inhibitor Inhibitor kinetics 127 156 11 Ion;substrate transport 55 95 12 mt-Membrane potential Mitochondrial membrane potential
- Bioblast links: Force and membrane potential - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
.::: Fundamental relationships
- mt-Membrane potential and protonmotive force
- O2k-Potentiometry
- » O2k-Catalogue: O2k-TPP+ ISE-Module
- » O2k-Manual: MiPNet15.03 O2k-MultiSensor-ISE
- » TPP - O2k-Procedures: Tetraphenylphosphonium
- » Specifications: MiPNet15.08 TPP electrode
- » Poster
- » Unspecific binding of TPP+
- » TPP+ inhibitory effect
- O2k-Potentiometry
- O2k-Fluorometry
- » O2k-Catalogue: O2k-FluoRespirometer
- » O2k-Manual: MiPNet22.11 O2k-FluoRespirometer manual
- » Safranin - O2k-Procedures: MiPNet20.13 Safranin mt-membranepotential / Safranin
- » TMRM - O2k-Procedures: TMRM
- O2k-Fluorometry
- O2k-Publications
99 151 13 Oxygen kinetics 98 131 14 Q-junction effect 12 54 15 Redox state 46 74 16 Substrate Fuel substrate kinetics 177 229 17 Temperature Temperature dependence 63 87 18 Threshold;excess capacity 27 30 19 Uncoupler Uncoupler kinetics 52 68
Coupling-control
# O2k-Publications MitoPedia: Coupling-control states Comment O2k Total 1 P 
OXPHOS capacity
Oxidative phosphorylation capacity, saturating [ADP] 2475 2679 2 R 
ROUTINE respiration
Physiological state, living cells 760 830 3 E 
ET capacity
Maximal noncoupled respiration 1734 1826 4 L 
LEAK respiration
Resting state, non-phosphorylating respiration 2173 2311
Pathway control
# O2k-Publications MitoPedia: Electron-transfer-pathway states Comment O2k Total 1 F F-pathway control state Fatty acid oxidation, level 5 516 613 2 N N-pathway control state NADH-linked, level 4 2101 2236 3 S S-pathway control state Succinate-linked, level 3 1413 1494 4 Gp Gp-pathway control state Glycerophosphate-linked, level 3 132 153 5 DQ Duorquinol-linked, level 2 18 23 6 CIV Complex IV single step Ascorbate & TMPD, level 1 594 622 7 NS NS-pathway control state Convergent CI- and CII-linked electron flow to the Q-junction 1311 1362 8 Other 126 143 9 ROX 
Residual oxygen consumption
includes non-mitochondrial respiration 1227 1273
MiPMap combinations - examples
- Examples for specific combinations
# O2k-Publications MitoPedia: Comment O2k Total 1 O2k-Publications: Human skeletal muscle 968 1189 2 O2k-Publications: Human heart 645 834 3 O2k-Publications: Skeletal muscle - human vs mouse 36 44
- Browse data
O2k-Manuals and protocols and specific instrumental applications
# O2k-Publications MitoPedia: Comment O2k Total 1 Twin-Flow respirometry 0 21 2 Separate DatLab applications 28 34