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O2k-Publications: Topics
- Mitochondria and Cell Research - the Oroboros Ecosystem
Contents
- 1 Mitochondrial physiology: MiP areas
- 2 Pathological states
- 3 Stress conditions
- 4 Organisms
- 5 Tissues and cells
- 6 Preparations
- 7 Enzymes
- 8 Regulation
- 9 Coupling-control states
- 10 Pathway control states
- 11 MiPMap combinations - examples
- 12 O2k-Manuals and protocols and specific instrumental applications
Mitochondrial physiology: MiP areas
# O2k-Publications MitoPedia: Comment O2k Total 1 mt-Medicine (354 entries) 354 483 2 Exercise physiology;nutrition;life style 635 881 3 Comparative MiP;environmental MiP 292 429 4 Pharmacology;toxicology 679 813 5 mt-Biogenesis;mt-density 232 306 6 Genetic knockout;overexpression 510 568 7 Instruments;methods 211 316
Pathological states
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Aging;senescence 230 356 2 Alzheimer's 60 81 3 Autism 3 7 4 Cancer 300 398 5 Cardiovascular 150 216 6 COPD 8 11 7 Diabetes 295 395 8 Inherited 60 81 9 Infectious 36 48 10 Myopathy 55 66 11 Neurodegenerative 145 200 12 Obesity 202 342 13 Parkinson's 52 83 14 Sepsis 61 71 15 Other 227 295
Stress conditions
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Cell death White, brown, beige fat tissue 87 144 2 Cryopreservation 34 57 3 Hypoxia 73 105 4 Ischemia-reperfusion 291 393 5 Oxidative stress;RONS 526 732 6 Permeability transition 66 87 7 Temperature: hypothermia; hyperthermia 85 102
Organisms
- Mammals
- Model organisms
# O2k-Publications MitoPedia: Comment O2k Total 1 Chicken (» Birds) 4 5 2 Zebrafish (» Fishes) 11 16 3 Drosophila (» Hexapods) 50 65 4 Caenorhabditis elegans (» Nematodes) 19 27 5 Artemia (» Crustaceans) 11 18 6 Saccharomyces cerevisiae (» Fungi) 52 72 7 Comparative MiP 292 429
- Non-mammals
# O2k-Publications MitoPedia: Comment O2k Total 1 Birds (» Chicken) 11 21 2 Reptiles turtles, lizards, snakes, crocodiles, alligators 10 14 3 Amphibians frogs, toads, salamanders 9 13 4 Fishes bony fishes, carilaginous fishes (sharks, rays, skates) and jawless fishes (hagfish, lampreys); » Zebrafish 99 129 5 Hexapods insects, springtails; » Drosophila 31 40 6 Crustaceans crabs, shrimp, barnacles, etc.; » Artemia 19 37 7 Annelids polychaetes, e.g. lugworm Arenicola marina, oligochaetes, leeches 3 16 8 Molluscs gastropods, cephalopods, bivalves 18 28 9 Nematodes » Caenorhabditis elegans 3 8 10 Other invertebrates urocordates (e.g. ascidians, sea squirts); cephalochordates (amphioxus, lancelets); echinoderms; chelicerates (e.g. spiders, scorpions, horseshoe crabs); myriapods (millipedes, centipedes); gastrotrichs; rotifers; ctenophores; nemerteans; tardigrades; platyhelminthes; cnidaria; porifera; ... 11 15 11 Fungi yeast, molds, mushrooms, etc.; » Saccharomyces cerevisiae 48 59 12 Plants 25 45 13 Protists amoebas, ciliates, trypanosomes, dinoflagellates, diatoms, green algae, etc. 30 42 14 Eubacteria true bacteria, cyanobacteria, spirochetes 23 39 15 Archaea archaebacteria 0 6
Tissues and cells
- Tissues - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Fat White, brown, beige fat tissue 152 213 2 Genital 81 110 3 Heart 610 791 4 Kidney 118 146 5 Liver 546 704 6 Lung;Gill 47 62 7 Nervous system 507 607 8 Skeletal muscle 919 1134
- Cell types - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Blood cells 218 268 2 Endothelial;epithelial;mesothelial cell 220 250 3 Fibroblast 170 216 4 Islet cell;pancreas;thymus 45 55 5 Leukemia 22 25 6 Lymphocyte 48 62 7 Platelets 102 120 8 Stem cells 30 40
- Cell lines - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 CHO 13 13 2 HEK 72 90 3 HeLa 29 42 4 Neuroblastoma 32 35 5 HUVEC 19 22 6 Macrophage-derived cell lines 24 33 7 Other cells and cell lines 268 305
Preparations
# O2k-Publications MitoPedia: Comment O2k Total 1 Living organism 42 211 2 Intact organ 21 34 3 Living cells 932 1031 4 Permeabilized cells 557 588 5 Permeabilized tissue 930 1014 6 Homogenate 292 327 7 Isolated mitochondria 1075 1344 8 SMP Submitochondrial particles 9 21 9 Chloroplasts 1 9 10 Enzyme 39 68 11 Oxidase and biochemical oxidation 38 48
Enzymes
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Adenine nucleotide translocase ANT 20 24 2 Complex I CI 425 509 3 Complex II;succinate dehydrogenase CII 375 444 4 Complex III CIII 286 330 5 Complex IV;cytochrome c oxidase CIV 386 453 6 Complex V;ATP synthase CV 207 245 7 mt-Inner membrane transporter 31 43 8 Marker enzyme 50 71 9 Supercomplex 41 54 10 TCA cycle and matrix dehydrogenases Tricarboxylic acid cycle 75 95 11 Uncoupling protein 57 62
Regulation
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 ADP ADP kinetics 145 190 2 ATP production 71 104 3 Aerobic glycolysis 41 76 4 Amino acid 9 18 5 Calcium 88 133 6 Coupling efficiency;uncoupling 71 132 7 Cyt c Cytochrome c 38 47 8 Fatty acid FA substrate kinetics 116 140 9 Flux control 46 73 10 Inhibitor Inhibitor kinetics 127 155 11 Ion;substrate transport 54 94 12 mt-Membrane potential Mitochondrial membrane potential
- Bioblast links: Force and membrane potential - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
.::: Fundamental relationships
- mt-Membrane potential and protonmotive force
- O2k-Potentiometry
- » O2k-Catalogue: O2k-TPP+ ISE-Module
- » O2k-Manual: MiPNet15.03 O2k-MultiSensor-ISE
- » TPP - O2k-Procedures: Tetraphenylphosphonium
- » Specifications: MiPNet15.08 TPP electrode
- » Poster
- » Unspecific binding of TPP+
- » TPP+ inhibitory effect
- O2k-Potentiometry
- O2k-Fluorometry
- » O2k-Catalogue: O2k-FluoRespirometer
- » O2k-Manual: MiPNet22.11 O2k-FluoRespirometer manual
- » Safranin - O2k-Procedures: MiPNet20.13 Safranin mt-membranepotential / Safranin
- » TMRM - O2k-Procedures: TMRM
- O2k-Fluorometry
- O2k-Publications
95 145 13 Oxygen kinetics 95 126 14 Q-junction effect 6 7 15 Redox state 45 70 16 Substrate Fuel substrate kinetics 175 227 17 Temperature Temperature dependence 59 82 18 Threshold;excess capacity 27 30 19 Uncoupler Uncoupler kinetics 52 68
Coupling-control states
# O2k-Publications MitoPedia: Coupling-control states Comment O2k Total 1 P 
OXPHOS capacity
Oxidative phosphorylation capacity, saturating [ADP] 2318 2514 2 R 
ROUTINE respiration
Physiological state, living cells 704 763 3 E 
ET capacity
Maximal noncoupled respiration 1603 1687 4 L 
LEAK respiration
Resting state, non-phosphorylating respiration 1999 2127
Pathway control states
# O2k-Publications MitoPedia: Electron-transfer-pathway states Comment O2k Total 1 F F-pathway control state Fatty acid oxidation, level 5 481 575 2 N N-pathway control state NADH-linked, level 4 1954 2074 3 S S-pathway control state Succinate-linked, level 3 1309 1380 4 Gp Gp-pathway control state Glycerophosphate-linked, level 3 122 140 5 DQ Duorquinol-linked, level 2 17 21 6 CIV Complex IV single step Ascorbate & TMPD, level 1 554 580 7 NS NS-pathway control state Convergent CI- and CII-linked electron flow to the Q-junction 1212 1258 8 Other 123 139 9 ROX 
Residual oxygen consumption
includes non-mitochondrial respiration 1117 1159
MiPMap combinations - examples
- Examples for specific combinations
# O2k-Publications MitoPedia: Comment O2k Total 1 O2k-Publications: Human skeletal muscle 919 1134 2 O2k-Publications: Human heart 610 791 3 O2k-Publications: Skeletal muscle - human vs mouse 36 44
- Browse data
O2k-Manuals and protocols and specific instrumental applications
# O2k-Publications MitoPedia: Comment O2k Total 1 Twin-Flow respirometry 0 21 2 Separate DatLab applications 26 32
