MitoEAGLE Verona 2016

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MiPsociety
COST Action CA15203 MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping


 

MitoEAGLE Verona 2016


Publications in the MiPMap
Verona IT, 2016 Nov 15-17. A roadmap for MitoEAGLE and first steps COST Action MitoEAGLE
COST Action MitoEAGLE

» http://www.cost.eu/COST_Actions/ca/CA15203

COST Association (2016-11-15) MitoGlobal

Abstract:
MitoEAGLE - Verona 15-17 Nov 2016: A roadmap for MitoEAGLE and first steps




COST Policies.png

Minutes

Download: MitoEAGLE Verona Meeting Minutes CA15203.docx
Find the WG summaries in the Minutes

General information

First Core Group Meeting, WG1 and WG4 Meeting
Date: 2016-11-15 to 2016-11-17
Venue: Verona, IT
Time schedule
  • 2016-11-15: Core Group Meeting 13:00 - 18:00
  • 2016-11-16: WG1/WG4 Meeting and Workshop 9:00 - 18:00
  • 2016-11-17: WG1/WG4 Meeting and Workshop 9:00 - 13:00
Arrival
  • By plane: shuttle bus from the Catullo airport to Porta Nuova station » More details
  • From the Train Station to the Centre: very quick by bus (13, 11, 12 please check direction Piazza Bra) or by taxi.


MitoEAGLE Working Groups

Goals and outputs

Goals and outputs are defined in the Work and Budget Plan Grant Period 1
Goals
  • Development of an interlaboratory proficiency ring test,
  • Draft of a manuscript on concepts and terminology of mitochondrial physiology,
  • Collect and discuss procedures and experimental protocols for the evaluation of mitochondrial capacities and create a Library of protocols: reference SUIT protocols, standard experimental media, and detailed instructions for OXPHOS analysis,
  • Kick-off meeting to develop a working plan for the establishment of consensus protocols, reporting schemes, and the assignment of specific study tasks for mitochondrial respiratory studies in blood and cultured cells,
  • Development of SOPs for blood cell separation.
Outputs
  • Roadmap of MitoEAGLE.
  • Roadmap of WG1.
  • First draft of position paper on MitoEAGLE (Lancet).
  • Concept of joint publications on nomenclature and terminology in mitochondrial physiology.
  • First steps on implementation of MitoFit Proficiency Test.
  • Roadmap for WG4.
  • Draft of methods manuscript on protocols for blood cell isolation and storage - summary of the state-of-the-art.


Programme

  • Last update 2016-10-31

November 15

Sala Zorzi (B), Palazzo Zorzi-Polfranceschi, Lungadige Porta Vittoria 17
Time Name and topic Materials and discussion
11:45 Lunch University restaurant, Via San Francesco 20
13:00 1. Core Group Meeting Work and Budget Plan Grant Period 1
13:10 Erich Gnaiger Erich Gnaiger, Chair (AT), Elisa Calabria Elisa Calabria, Vice chair (IT): A road map for MitoEAGLE Memorandum of Understanding
1.1. Road map and first steps of Working Groups

13:20 Pablo Garcia-Roves Garcia-Roves PM (ES): WG2 MitoEAGLE data repository in muscle tissues Proposal

Icons-mini-file acrobat.gif Presentation: WG2

13:35 Strategy
13:50 Zuzana Cervinkova Cervinkova Z (CZ): WG3 MitoEAGLE data repository on fat, neurol and liver tissues Proposal

Icons-mini-file acrobat.gif Presentation: WG3 - Liver

14:05 Strategy
14:20 Elisa Calabria Calabria E (IT): WG4 MitoEAGLE data: blood and cultured cells Proposal

Icons-mini-file acrobat.gif Presentation: WG4

14:30 Strategy
14:40 Kathrin Renner-Sattler Renner-Sattler K (DE): WG1 Standard operating procedures and user requirement document: Protocols, terminology, documentation Proposal

Icons-mini-file acrobat.gif Presentation: WG1

14:50 Strategy
15:00 Magdalena Labieniec-Watala Labieniec-Watala M (PL): Short-Term Scientific Missions (STSMs) Grant Periods 1 and 2 STSMs MitoEAGLE

Icons-mini-file acrobat.gif Presentation:STSMs

15:15 Strategy
15:30 Coffee
1.2. Dissemination plan

16:00 Marina Makrecka Makrecka-Kuka M (LV): Dissemination plan MitoEAGLE.docx »Discussion

Icons-mini-file acrobat.gif Presentation: Dissemination

16:15 MitoEAGLE flyer »Discussion
1.3. Prepare agenda for MC Meeting Barcelona Programme coordinators link the specific topics to the global MitoEAGLE targets.
16:40 Pablo Garcia-Roves Garcia-Roves PM (ES): General outline Icons-mini-file acrobat.gif Presentation: Barcelona Meeting
16:50 Erich Gnaiger Gnaiger E (AT): Training School in Obergurgl, Tyrol/Austria in July 2017 MiPschool Obergurgl 2017
17:00 Other networking activities
17:10 Next Management Committee Meeting in an Inclusiveness Target Country, Grant Period 2 »Discussion
17:20 Nina Krako Krako N (RS): Implementation strategy: plan towards inclusiveness (geographical coverage, early career investigator involvement and gender balance) that is revised and updated at every MC meeting and develop a strategy to attract researchers and stakeholders. »Discussion

Icons-mini-file acrobat.gif Presentation: Inclusiveness

17:30 Laner Verena Laner V (AT): Aiming to support the involvement of researchers from Near Neighbour (NNC) and International Partner Countries (IPC) in MitoEAGLE - networking with the Mitochondrial Physiology Society - on the basis of mutual benefit. - »Discussion

Icons-mini-file acrobat.gif Presentation: MiPsociety

17:40 Presentations of independently funded projects, according to the Memorandum of Understanding.
17:50-18:00 Pablo Garcia-Roves Garcia-Roves PM (ES): Summary.
18:30 Dinner Pizzeria Du de Coppe, Galleria Pellicciai


November 16

Sala Barbieri, Palazzo Giuliari, Via dell’Artigliere 8
Time Name and topic Materials and discussion
09:00 MitoEAGLE Working Groups Verona Meeting
09:05 Prof. Andrea Sbarbati, Director of Dept Neurosciences, Biomedicine and Movement Sciences, Univ Verona: Welcome
09:10 Prof. Federico Schena, Dept Neurological and Movement Sciences, Section of Motor Sciences, Univ Verona: Welcome
09:15 Elisa Calabria Calabria E (IT): Summary of Core Group meeting: relevant topics
2. WG1 meeting: MitoEAGLE protocols, terminology, documentation Programme coordinator: Erich Gnaiger
2.1. Discussion of concepts and terminology of mitochondrial physiology TG1.1 Coupling states and coupling control ratios: consensus statements

09:30 Erich Gnaiger Gnaiger E (AT): Towards a database: why terminology is important. - MitoEAGLE: Respiratory states »Discussion
10:00 Wuest RC (NL): On terminology for mitochondrial respiration using different substrates. Icons-mini-file acrobat.gif Presentation: Wüst R
2.2. TG1.2 SUIT protocols: concept and nomenclature suitable for a database.

10:20 Carolina Doerrier Doerrier C (AT): Approaches for finding a SUIT reference protocol. MitoPedia: SUIT
10:50 Coffee
11:20 Sameh Ali Ali SS (EG): Oxygen consumption and ROS production - challenges for evaluation of experimental protocols. Icons-mini-file acrobat.gif Presentation: Ali SS
11:50 Roberto Scatena Scatena R (IT): Mitochondrial respiratory complexes as targets of drugs - critical importance of protocols: intact vs permeabilized cells, incubation time. Icons-mini-file acrobat.gif Presentation: Scatena R
12:15-12:20 General discussion.
12:45 Lunch University restaurant, Via San Francesco 20
2.3. TG1.5 Knowledge management system

14:00 Michael Drinnan Drinnan M (AT, UK): Data management: direction of travel.
14:30 Pablo Garcia-Roves Garcia-Roves PM (ES): Design and implementation of systems biology approaches to integrate heterogenic data in biomedical research.
15:00 Vendelin M (EE): A mitochondrial physiology database for the laboratory.
15:30 Kathrin Renner-Sattler Renner-Sattler K (DE): Summary Roadmap Working Group 1 Icons-mini-file acrobat.gif Presentation: Renner-Sattler K
16:00 Coffee
3. WG4 meeting: MitoEAGLE data: blood and cultured cells - TG4.1 Blood: Develop a working plan for the establishment of consensus protocols, reporting schemes, and the assignment of specific study tasks for mitochondrial respiratory studies in blood cells. Programme coordinator: Elisa Calabria
3.1. PBMCs

16:30 Elisa Calabria Calabria E (IT): Blood cells mitochondrial activity in aging and frailty. Discussion

Icons-mini-file acrobat.gif Presentation: Calabria E

17:00 Zuzana Sumbalova Sumbalova Z (AT, SK): Isolation of blood cells for high-resolution respirometry: PBMCs and platelets. MiPNet21.17 BloodCellsIsolation

Icons-mini-file acrobat.gif Presentation: Sumbalova Z

17:30 Chiara Volani Volani C (AT): Human and rat PBMCs: what can we do better? Icons-mini-file acrobat.gif Presentation: Volani C
17:45-18:00 Keppner G (DE): Isolation of PBMCs for high-resolution respirometry and association to basal metabolic rate. Icons-mini-file acrobat.gif Presentation: Keppner G
18:30 Dinner Ristorante al Torcolo, Via C. Cattaneo, 11b


November 17

Sala Barbieri, Palazzo Giuliari, Via dell’Artigliere 8
Time Name and topic Materials and discussion
3.2. Platelets

09:00 Eleonor Asander Frostner Aasander Frostner E (SE): Mitochondrial respiration in human viable platelets.
09:30 Luiz Felipe Garcia e Souza Garcia-Souza LF (AT): Mitochondrial respiratory control in platelets. MitoFit-Bloodcells
10:00 Emil Westerlund Westerlund E (SE): The role of platelet respirometry in diagnosing mitochondrial disease.
10:30 Coffee
11:00-11:30 Discussion: Development of SOPs for blood cell separation and respiration. Working Group 4
4. MitoEAGLE Agenda

11:30-12:30 A roadmap to publications: MitoEAGLE terminology; respiratory protocols Working Group 1
12:30-13:00 Summary for programme of Barcelona MC and WG meeting - MitoEAGLE next steps - on the wing MitoEAGLE Barcelona 2017
13:00 Lunch University restaurant, Via San Francesco 20


Participants

(Attendance list)
Country Participant
Sameh Ali
EG Ali Sameh
EG Aly Enji
Eleonor Asander Frostner
SE Asander Frostner Eleonor
Elisa Calabria
IT Calabria Elisa
Zuzana Cervinkova
CZ Cervinkova Zuzana
Carolina Doerrier
AT Doerrier Velasco Carolina
Michael Drinnan
UK Drinnan Michael
TR Engin Ayse Basak
Luiz Felipe Garcia e Souza
AT Garcia e Souza Luiz Felipe
Pablo Garcia-Roves
ES Garcia-Roves Pablo M
Maria Luisa Genova
IT Genova Maria Luisa
Erich Gnaiger
AT Gnaiger Erich
IT Guida Marianna
EE Kaambre Tuuli
DE Keppner Gloria
Nina Krako
RS Krako Nina
Magdalena Labieniec-Watala
PL Labieniec-Watala Magdalena
Laner Verena
AT Laner Verena
Marina Makrecka
LV Makrecka-Kuka Marina
PL Michalak Slawomir
Christina Plattner
AT Plattner Christina
Kathrin Renner-Sattler
DE Renner-Sattler Kathrin
Roberto Scatena
IT Scatena Roberto
IT Schena Federico
Zuzana Sumbalova
AT Sumbalova Zuzana
IT Tiolo Gaia
EE Vendelin Marko
Chiara Volani
AT Volani Chiara
Emil Westerlund
SE Westerlund Emil
NL Wüst Rob C


Venue

  • Day 1 (afternoon): Sala Zorzi (B), Palazzo Zorzi-Polfranceschi, Lungadige Porta Vittoria 17
  • Day 2: Sala Barbieri, Palazzo Giuliari, Via dell’Artigliere 8
  • Day 3: Sala Barbieri, Palazzo Giuliari, Via dell’Artigliere 8
Lunch: University restaurant, Via San Francesco 20 (for registrations received until 15 days in advance)


Accomodation

The following hotels are recommended - please mention 'MitoEAGLE' in your reservation
Hotel Giulietta & Romeo (fully booked)
http://www.giuliettaeromeo.it
info@hotelgr.it
EUR 89.00 (double room used as a single room with breakfast)
Hotel Milano - reservation deadline: Nov 5
http://www.hotels2go.it/
info@hotels2go.it
Classic room: EUR 94.00 (double room used as a single room with breakfast)
Executive room: EUR 102.00


Financial COST support

Financial support for the Verona meeting is defined in the Work and Budget Plan Grant Period 1. Priority will be given to the Core Group and to participants with specific presentations listed in the programme.
All participants (limited to 30-40 researchers)
  • Registration fees: waived.
  • Lunch and coffee breaks: free, for registrations received until 15 days in advance.
20 participants
  • Travel and daily allowance: see COST Vademecum
  • Accomodation revised flat rate: 95 EUR (according to the e-vote by the Management Committee)


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