Madreiter-Sokolowski 2019 FEBS J

From Bioblast
Publications in the MiPMap
Madreiter-Sokolowski CT, Ramadani-Muja J, Ziomek G, Burgstaller S, Bischof H, Koshenov Z, Gottschalk B, Malli R, Graier WF (2019) Tracking mitochondria's intra- and inter-organelle signaling. FEBS J 286:4378-401.

Β» PMID: 31661602 Open Access

Madreiter-Sokolowski CT, Ramadani-Muja J, Ziomek G, Burgstaller S, Bischof H, Koshenov Z, Gottschalk B, Malli R, Graier WF (2019) FEBS J

Abstract: Mitochondria are as highly specialized organelles and masters of the cellular energy metabolism in a constant and dynamic interplay with their cellular environment, providing adenosine trisphosphate, buffering Ca2+ and fundamentally contributing to various signaling pathways. Hence, such broad field of action within eukaryotic cells requires a high level of structural and functional adaptation. Therefore, mitochondria are constantly moving and undergoing fusion and fission processes, changing their shape and their interaction with other organelles. Moreover, mitochondrial activity gets fine-tuned by intra- and inter-organelle H+, K+, Na+ and Ca2+ signaling. In this review we provide an up-to-date overview on mitochondrial strategies to adapt and respond to, as well as affect, their cellular environment. We also present cutting-edge technologies used to track and investigate subcellular signaling, essential to the understanding of various physiological and pathophysiological processes.

Β© 2019 Federation of European Biochemical Societies. β€’ Keywords: Calcium, Intracellular signaling, Mitochondria, Mitochondria-associated ER membranes, Mitochondrial membrane potential, Mitochondrial structure, Potassium β€’ Bioblast editor: Plangger M


Labels: MiParea: Respiration, mt-Structure;fission;fusion 





HRR: Oxygraph-2k 

Labels, 2019-11 

Cookies help us deliver our services. By using our services, you agree to our use of cookies.