Lee 2019 J Diabetes Investig
| Lee HK (2019) Fatty acid overload to compromised OXPHOS activates inflammation in type 2 diabetes - hidden beasts and how to find them? J Diabetes Investig 11:290-93. |
Lee HK (2019) J Diabetes Investig
Abstract: Epidemic of type 2 diabetes (T2D) and obesity are considered as consequences of lifestyle changes came with industrialization, overconsumption of calorie-dense fatty foods accompanied by less exercise. Because obese subjects have high blood insulin levels while they maintain normal blood glucose, ineffectiveness of insulin or insulin resistance (IR) became key biochemical abnormality to understand obesity. As insulin deficiency is hallmark of diabetes, relative insulin deficiency to compensate IR is considered to cause type 2 diabetes.
© 2019 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd. • Keywords: Inflammation, Insulin resistance, Mitochondrial dysfunction • Bioblast editor: Plangger M • O2k-Network Lab: KR Seoul Lee HK
Labels: MiParea: Respiration
Pathology: Diabetes
HRR: Oxygraph-2k
Labels, 2019-11, KR
