Carbohydrates, also known as saccharides, are molecules composed of carbon, hydrogen and oxygen. These molecules can be divided by size and complexity into monosaccharides, disaccharides, oligosaccharides, and polysaccharides. Glucose is a monosaccharide considered the primary source of energy in cells and a metabolic intermediate. This carbohydrate undergoes glycolysis, with the generation of pyruvate, that can enter the TCA cycle.
Carbohydrates such as glucose and fructose may also be involved in the Crabtree effect.
MitoPedia topics: Substrate and metabolite
SUITbrowser question: Carbohydrate
- SUIT protocols can be focused on the analysis of carbohydrate metabolism. Pyruvate is formed in glycolysis and is decarboxylated in the mt-matrix by the pyruvate dehydrogenase, generating acetyl-CoA. The addition of other substrates (M, S) is necessary for further steps of the TCA cycle.
- The SUITbrowser can be used to find the best SUIT protocols to analyze carbohydrate metabolism, among other research questions.