Aon 2015 Antioxid Redox Signal
|Aon MA, Foster DB (2015) Diabetic cardiomyopathy and the role of mitochondrial dysfunction: novel insights, mechanisms, and therapeutic strategies. Antioxid Redox Signal 22:1499-501.|
Abstract: This Forum addresses the role of mitochondrial dysfunction in the multifactorial nature of diabetic cardiomyopathy (DCM) from multiple angles. Contributors deliver a diverse and in-depth view of the state-of-the-art in DCM, from bench to bedside. What emerges is a picture of mitochondrial dysfunction as a central upstream defect, inflicted on the heart by diabetes. Collectively, the authors pinpoint high-value knowledge gaps, propose new conceptual frameworks, and highlight understudied, but promising, research themes.
Labels: MiParea: mt-Structure;fission;fusion, mtDNA;mt-genetics, Exercise physiology;nutrition;life style, mt-Medicine, Patients, mt-Awareness Pathology: Cardiovascular, Diabetes Stress:Oxidative stress;RONS Organism: Human