Alvarez-Luis 2024 MitoFit
| Alvarez-Luis J, Gama-Perez P, Garcia-Roves PM (2024) Exploring Mitochondrial Adaptability: Key to Overcoming Obesity and Enhancing Metabolic Health. MitoFit Preprints 2024.5. https://doi.org/10.26124/mitofit:2024-0005 |
» MitoFit Preprints 2024.5.
Exploring Mitochondrial Adaptability: Key to Overcoming Obesity and Enhancing Metabolic Health.
Alvarez-Luis Jorge, Gama Perez Pau, Garcia-Roves Pablo M (2024) MitoFit Prep
Abstract: The management of obesity is critical and has traditionally included surgical interventions like bariatric surgery and pharmacological treatments. However, these methods have limitations when applied in isolation, which limits their effectiveness in completely reversing the condition. A comprehensive approach that considers the unique properties of adipose tissue and evaluates additional parameters—such as the ratio of lean mass to fat and insulin sensitivity—can offer a more nuanced understanding of obesity. Moreover, lifestyle modifications have been shown to significantly influence the performance of cellular organelles responsible for maintaining bodily homeostasis, including mitochondria. This analysis explores into the impact of obesity on mitochondrial function and the potential for lifestyle changes to influence this relationship.
• Keywords: obesity, metabolic disease, white adipose tissue, mitochondria, metabolic plasticity
• Bioblast editor: Tindle-Solomon L
• O2k-Network Lab: ES Barcelona Garcia-Roves PM
ORCID: Alvarez-Luis Jorge, 
Gama Perez Pau, Garcia-Roves Pablo M
Labels: MiParea: Exercise physiology;nutrition;life style
Pathology: Obesity
