Talk:Oroboros Laboratory: Difference between revisions

Revision as of 08:41, 7 August 2017

Picked up - reading and discussion

As we go

2017-07-31 Don't run biomedical science as a business

2017-07-19 Article not only about the shipping of frozen PBMC: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010910/ Velikab (talk)

2017-07-11 A very brief comparison of O2k vs. Seahorse: Li 2017 Methodist Debakey Cardiovasc J

The Oroboros high-resolution respirometer ... can perform multiple injections sequentially for substrates and chemicals. This makes the Oroboros more flexible for comparison purposes. >> O2k-Feedback

2017-06-19 Gdynia_2016_Nat Commun - Malic enzyme; cancer

2017-06-08 Patent of Q-electrode (1988): Dr P.R. Rich, Glynn Res. Ph., Bodmin; European Patent no.85900699.1 Hungerm (talk) 10:18, 21 June 2017 (CEST)

2017-06-08 Pre-print publication: Mitochondria are physiologically maintained at close to 50 °C »Bioblast link«

2017-05-30 Quote of the day: ".. oligomycin (complex V inhibitor) determines the amount of ATP production is linked to respiration, FCCP (mitochondrial uncoupler) enables measurement of maximal respiratory capacity, while a combination of rotenone (complex I inhibitor) and antimycin A (complex III inhibitor) determines the reserved respiratory capacity." .. and more: "The mitochondrial network is a major site of ATP production through the coupled integration of the electron transport chain (ETC) with oxidative phosphorylation." - Trotta et al (2017) Disruption of mitochondrial electron transport chain function potentiates the pro-apoptotic effects of MAPK inhibition. JBC Papers in Press. Published on May 25, 2017 as Manuscript M117.786442.

What is reserved respiratory capacity?

2017-05-22: Komlodi 2017 Neuropharmacology

Various

Warburg effect

Warburg O (1956) On the origin of cancer cells. Science 123:309-14.
Warburg O (1956) On respiratory impairment in cancer cells. Science 124:269-70.
Vander Heiden MG, Cantley LC, Thompson CB (2009) Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324: 1029-33.
Kim JW, Dang CV (2006) Cancer’s molecular sweet tooth and the Warburg effect. Cancer Res 66:8927-30.
Review: http://online.liebertpub.com/doi/full/10.1089/ars.2016.6750
Review: http://onlinelibrary.wiley.com/doi/10.1111/febs.13402/full

To our editors

OROBOROS Mitochondrial Research Laboratory was moved to Oroboros MitoFit Laboratory

>> Please check redirects from OROBOROS Mitochondrial Research Laboratory

OROBOROS MitoLab: visiting scientists was moved to roboros MitoFit lab: visiting scientists

>> Please check redirects from OROBOROS MitoLab: visiting scientists

Rationale: The 'MitoFit Centre of Excellence' or the 'MitoFit Core Facility' will be comprise of the Oroboros MitoFit Laboratory and the DSL MitoFit Facility.

Popular Bioblast page

Oroboros MitoFit Laboratory has been accessed more than

5,000 times (2017-07-05)

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 === As we go ===
+* 2017-07-31 [https://www.nature.com/polopoly_fs/1.22366!/menu/main/topColumns/topLeftColumn/pdf/547381a.pdf Don't run biomedical science as a business]
+* 2017-07-19 Article not only about the shipping of frozen PBMC: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010910/ [[User:Velikab|Velikab]] ([[User talk:Velikab|talk]])
+* 2017-07-11 A very brief comparison of '''O2k vs. Seahorse''':    [[Li 2017 Methodist Debakey Cardiovasc J]]
+::::::: ''The Oroboros high-resolution respirometer ... can perform multiple injections sequentially for substrates and chemicals. This makes the Oroboros more flexible for comparison purposes.'' >> [[O2k-Feedback]]
 * 2017-06-19 [[Gdynia_2016_Nat Commun]] - Malic enzyme; cancer