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...tion of ischemia/reperfusion injury: effects of a soluble adenylyl cyclase inhibitor LRE1. ...a setting of rodent model of hepatic IR. Therefore, we tested LRE1 (a sAC inhibitor) administration before I/R.

...tion induced by PA was observed by treatment with diphenylene iodonium, an inhibitor of NADPH oxidase. The participation of this enzyme complex was confirmed th

|mitopedia topic=Inhibitor

|description=Triethyltin bromide (TET) is a lipophilic [1] inhibitor of the mitochondrial [[ATP synthase]] [2] which is used to induce [[LEAK st |mitopedia topic=Inhibitor

...its capability of acting as both a protonophore and an unusual complex II inhibitor, which interferes with the mitochondrial respiration by blocking the electr |keywords=Complex II inhibitor, Mitochondria, Q(d)-binding site, Superoxide anion, Triclosan, Uncoupler

...nveiled mitochondrial dysfunction upon exposure to the FDA-approved kinase inhibitor sunitinib. This seemingly context-dependent side effect of this drug highli ...cells, cell bioenergetics, cell culture media, cell proliferation, kinase inhibitor, mitochondrial function

...cooling was without interruption. The newly established multiple substrate-inhibitor titration provides the possibility to measure complex I dependent functiona ...r technique, respirometry, mitochondria, mitochondrial function, substrate-inhibitor-titration, mitochondrial encephalomyopathy, shipment of samples

...of mitochondrial respiration, FCCP, a protonophore, nor propyl gallate, an inhibitor of the plastid terminal oxidase, induced such a strong effect like antimyci

...act=Human mitochondrial malic enzyme is a regulatory enzyme with ATP as an inhibitor. Structural studies reveal that the enzyme has two ATP-binding sites, one a |topics=ATP, Inhibitor

|keywords=3-Bromopyruvate, Glycolytic inhibitor, Mitochondrial respiration inhibitor, Alkylation,Tumor cell metabolism

..., ADP and glutamate (GMO(3) ), + succinate (GMOS(3) ), + uncoupler (U) and inhibitor (rotenone) of complex I respiration. Citrate synthase (CS) activity was mea |keywords=AMPKα2 kinase-dead (KD) mice; substrate-uncoupler-inhibitor-titration (SUIT) protocol

...ma S, Yokota T, Tanaka S, Okita K, Tsutsui H (2016) Dipeptidyl peptidase-4 inhibitor improved exercise capacity and mitochondrial biogenesis in mice with heart ...igated the effects of the administration of a dipeptidyl peptidase (DPP)-4 inhibitor on the exercise capacity and skeletal muscle abnormalities in an HF mouse m

...d soluble F₁-ATPase. Activity assays and immunodetection of the inhibitor protein IF₁ were used and combined with molecular docking analys ''Key Results'': T1AM is a non-competitive inhibitor of F₀F₁-ATPsynthase whose binding is mutually exclusi

...r), ODQ (a GC inhibitor), PP2 (a src kinase inhibitor), and KT-5823 (a PKG inhibitor) abolished preconditioning by BK and blocked the inotropic response to ouab |topics=Cyt c, Inhibitor, Ion;substrate transport

...O(2)(-) generation in control cells, or those treated with the NO synthase inhibitor, when incubated at 21% O(2). However, after 30-min exposure of control cell |topics=Cyt c, Flux control, Inhibitor, Oxygen kinetics, Redox state

...Wang Z, Rhee KY, Ding K, Zhang T, Cook GM (2018) A pyrazolo[1,5-a]pyridine inhibitor of the respiratory cytochrome bcc complex for the treatment of drug-resista ...infection. Here, we characterize a putative respiratory complex III (QcrB) inhibitor, TB47: a pyrazolo[1,5-a]pyridine-3-carboxamide. TB47 is active (MIC between

...ediated pAkt while increased pAMPK regardless of insulin. Reciprocally, an inhibitor of Akt, triciribine (TCN), decreased cellular ATP contents. Overexpression

...) and diacylglycerol (DAG) content was significantly attenuated with DPP-4 inhibitor treatment. In addition, MK0626 significantly reduced mitochondrial incomple ...rds=Lipidomics, NAFLD, Obesity, Hepatic insulin resistance, MK-0626 (DPP-4 inhibitor)

...et''' contains the sequential titrations in a specific Substrate-uncoupler-inhibitor titration (SUIT) protocol. The laboratory titration sheets for different SU

...GA, Doshi A, Zaware N, Gangjee A, Ihnat MA (2016) AG311, a small molecule inhibitor of complex I and hypoxia-induced HIF-1α stabilization. Cancer Lett pii: S0 ...nd animals with AG311 and dichloroacetate, a pyruvate dehydrogenase kinase inhibitor that increases oxidative metabolism, resulted in synergistic cell kill and