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From Bioblast
 YearReferenceTissue and cellCell lineMammal and modelNonmammal
Andrade 2021 Biochim Biophys Acta Mol Cell Biol Lipids2021Andrade ML, Gilio GR, Perandini LA, Peixoto AS, Moreno MF, Castro E, Oliveira TE, Vieira TS, Ortiz-Silva M, Thomazelli CA, Chaves-Filho AB, Belchior T, Chimin P, Magdalon J, Ivison R, Pant D, Tsai L, Yoshinaga MY, Miyamoto S, Festuccia WT (2021) PPARγ-induced upregulation of subcutaneous fat adiponectin secretion, glyceroneogenesis and BCAA oxidation requires mTORC1 activity. Biochim Biophys Acta Mol Cell Biol Lipids 1866:158967.FatMouse
Liang 2021 Biomed Pharmacother2021Liang L, Zhang G, Cheng C, Li H, Jin T, Su C, Xiao Y, Bradley J, Peberdy MA, Ornato JP, Mangino MJ, Tang W (2021) High-resolution respirometry for evaluation of mitochondrial function on brain and heart homogenates in a rat model of cardiac arrest and cardiopulmonary resuscitation. Biomed Pharmacother 142:111935.Heart
Nervous system
Rat
Bandara 2021 BMC Mol Cell Biol2021Bandara AB, Drake JC, Brown DA (2021) Complex II subunit SDHD is critical for cell growth and metabolism, which can be partially restored with a synthetic ubiquinone analog. https://doi.org/10.1186/s12860-021-00370-w
Ouillon 2021 J Exp Biol2021Ouillon N, Sokolov EP, Otto S, Rehder G, Sokolova IM (2021) Effects of variable oxygen regimes on mitochondrial bioenergetics and reactive oxygen species production in a marine bivalve Mya arenaria. J Exp Biol 224:jeb237156.
Cardoso 2021 BEC MgG2021Cardoso LHD, Doerrier C, Gnaiger E (2021) Magnesium Green for fluorometric measurement of ATP production does not interfere with mitochondrial respiration. Bioenerg Commun 2021.1. https://doi.org/10.26124/bec:2021-0001HeartMouse
Kaspar 2021 Sci Adv2021Kaspar S, Oertlin C, Szczepanowska K, Kukat A, Senft K, Lucas C, Brodesser S, Hatzoglou M, Larsson O, Topisirovic I, Trifunovic A (2021) Adaptation to mitochondrial stress requires CHOP-directed tuning of ISR. Sci Adv 7:0971.HeartMouse
Scheffer 2021 Brain Commun2021Scheffer DDL, Freitas FC, Aguiar AS Jr, Ward C, Guglielmo LGA, Prediger RD, Cronin SJF, Walz R, Andrews NA, Latini A (2021) Impaired dopamine metabolism is linked to fatigability in mice and fatigue in Parkinson's disease patients. Brain Commun 3:fcab116.Skeletal muscleRat
Yin 2021 Nat Commun2021Yin Z, Burger N, Kula-Alwar D, Aksentijević D, Bridges HR, Prag HA, Grba DN, Viscomi C, James AM, Mottahedin A, Krieg T, Murphy MP, Hirst J (2021) Structural basis for a complex I mutation that blocks pathological ROS production. Nat Commun 12:707.
Whitehead 2021 Nat Commun2021Whitehead A, Krause FN, Moran A, MacCannell ADV, Scragg JL, McNally BD, Boateng E, Murfitt SA, Virtue S, Wright J, Garnham J, Davies GR, Dodgson J, Schneider JE, Murray AJ, Church C, Vidal-Puig A, Witte KK, Griffin JL, Roberts LD (2021) Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis. Nat Commun 12:1905.Skeletal muscleHuman
Styles 2021 Cell Death Dis2021Styles FL, Al-Owais MM, Scragg JL, Chuntharpursat-Bon E, Hettiarachchi NT, Lippiat JD, Minard A, Bon RS, Porter K, Sukumar P, Peers C, Roberts LD (2021) Kv1.3 voltage-gated potassium channels link cellular respiration to proliferation through a non-conducting mechanism. Cell Death Dis 12:372.HEKHuman
Moon 2021 J Lipid Res2021Moon SH, Dilthey BG, Liu X, Guan S, Sims HF, Gross RW (2021) High-Fat diet activates liver iPLA2γ generating eicosanoids that mediate metabolic stress. J Lipid Res 62:100052.LiverMouse
Honecker 2021 Int J Obes (Lond)2021Honecker J, Weidlich D, Heisz S, Lindgren CM, Karampinos DC, Claussnitzer M, Hauner H (2021) A distribution-centered approach for analyzing human adipocyte size estimates and their association with obesity-related traits and mitochondrial function. Int J Obes (Lond) [Ephub ahead of print].FatHuman
Colin 2021 J Cell Mol Med2021Colin M, Dechene L, Ceusters J, Niesten A, Demazy C, Lagneaux L, Zouaoui Boudjeltia K, Franck T, Van Antwerpen P, Renard P, Mathieu V, Serteyn D (2021) Priming of mesenchymal stem cells with a hydrosoluble form of curcumin allows keeping their mesenchymal properties for cell-based therapy development. J Cell Mol Med 25:4877-81.Stem cellsHorse
Akinbiyi 2021 Sci Rep2021Akinbiyi EO, Abramowitz LK, Bauer BL, Stoll MSK, Hoppel CL, Hsiao CP, Hanover JA, Mears JA (2021) Blocked O-GlcNAc cycling alters mitochondrial morphology, function, and mass. Sci Rep 11:22106.
Tonnesen 2021 Mol Cell Biochem2021Tonnesen PT, Hjortbak MV, Lassen TR, Seefeldt JM, Bøtker HE, Jespersen NR (2021) Myocardial salvage by succinate dehydrogenase inhibition in ischemia-reperfusion injury depends on diabetes stage in rats. Mol Cell Biochem 476:2675-84.HeartRat
Hansen 2021 Physiol Rep2021Hansen C, Olsen K, Pilegaard H, Bangsbo J, Gliemann L, Hellsten Y (2021) High metabolic substrate load induces mitochondrial dysfunction in rat skeletal muscle microvascular endothelial cells. Physiol Rep 9:e14855.Skeletal muscle
Endothelial;epithelial;mesothelial cell
Rat
King 2021 J Biol Chem2021King WT, Axelrod CL, Zunica ERM, Noland RC, Davuluri G, Fujioka H, Tandler B, Pergola K, Hermann GE, Rogers RC, López-Domènech S, Dantas WS, Stadler K, Hoppel CL, Kirwan JP (2021) Dynamin-related protein 1 regulates substrate oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics. J Biol Chem 297:101196.Skeletal muscleMouse
Abdel-Rahman 2021 Free Radic Res2021Abdel-Rahman EA, Zaky EA, Aboulsaoud M, Elhossiny RM, Youssef WY, Mahmoud AM, Ali SS (2021) Autism spectrum disorder (ASD)-associated mitochondrial deficits are revealed in children's platelets but unimproved by hyperbaric oxygen therapy. Free Radic Res 55:26-40.
Mailloux 2021 Redox Biol2021Mailloux RJ (2021) An update on methods and approaches for interrogating mitochondrial reactive oxygen species production. Redox Biol 45:102044. https://doi.org/10.3390/antiox9060472
Hamm 2021 Mol Ther Methods Clin Dev2021Hamm SE, Fathalikhani DD, Bukovec KE, Addington AK, Zhang H, Perry JB, McMillan RP, Lawlor MW, Prom MJ, Vanden Avond MA, Kumar SN, Coleman KE, Dupont JB, Mack DL, Brown DA, Morris CA, Gonzalez JP, Grange RW (2023) Voluntary wheel running complements microdystrophin gene therapy to improve muscle function in mdx mice. https://doi.org/10.1016/j.omtm.2021.02.024Skeletal muscleMouse
Liu 2021 Front Physiol2021Liu H, Tenzing N, van Patot MT, Qile M, Ge RL, Wuren T (2021) Enhanced placental mitochondrial respiration in Tibetan women at high altitude. Front Physiol 12:697022. doi: 10.3389/fphys.2021.697022GenitalHuman
Schmidt 2021 Cancer Metab2021Schmidt CA, McLaughlin KL, Boykov IN, Mojalagbe R, Ranganathan A, Buddo KA, Lin CT, Fisher-Wellman KH, Neufer PD (2021) Aglycemic growth enhances carbohydrate metabolism and induces sensitivity to menadione in cultured tumor-derived cells. Cancer Metab 9:3.LiverHuman
Connell 2021 J Nutr2021Connell NJ, Grevendonk L, Fealy CE, Moonen-Kornips E, Bruls YMH, Schrauwen-Hinderling VB, de Vogel J, Hageman R, Geurts J, Zapata-Perez R, Houtkooper RH, Havekes B, Hoeks J, Schrauwen P (2021) NAD+-precursor supplementation with L-tryptophan, nicotinic acid, and nicotinamide does not affect mitochondrial function or skeletal muscle function in physically compromised older adults. J Nutr 151:2917-31Skeletal muscleHuman
Tungtur 2021 Sci Rep2021Tungtur SK, Wilkins HM, Rogers RS, Badawi Y, Sage JM, Agbas A, Jawdat O, Barohn RJ, Swerdlow RH, Nishimune H (2021) Oxaloacetate treatment preserves motor function in SOD1G93A mice and normalizes select neuroinflammation-related parameters in the spinal cord. Sci Rep 11:11051.Nervous systemMouse
Branco Haas 2021 Thesis2021Branco Haas C (2021) Insulin signaling and microglia in the young and aged brain. PhD Thesis 135.
Koch 2021 Trends Ecol Evol2021Koch RE, Buchanan KL, Casagrande S, Crino O, Dowling DK, Hill GE, Hood WR, McKenzie M, Mariette MM, Noble DWA, Pavlova A, Seebacher F, Sunnucks P, Udino E, White CR, Salin K, Stier A (2021) Integrating mitochondrial aerobic metabolism into ecology and evolution. Trends Ecol Evol 36:321-32.
Wall 2021 Dis Model Mech2021Wall JM, Basu A, Zunica ERM, Dubuisson OS, Pergola K, Broussard JP, Kirwan JP, Axelrod CL, Johnson AE (2021) CRISPR/Cas9-engineered Drosophila knock-in models to study VCP diseases. Dis Model Mech 14:dmm048603.Skeletal muscleDrosophila
Bouche 2021 PLoS One2021Bouche L, Kamel R, Tamareille S, Garcia G, Villedieu C, Pillot B, Gueguen N, Chehaitly A, Chao de la Barca JM, Beaumont J, Baetz D, Ovize M, Sesaki H, Henrion D, Reynier P, Lenaers G, Prunier F, Mirebeau-Prunier D (2021) DRP1 haploinsufficiency attenuates cardiac ischemia/reperfusion injuries. PLoS One 16:0248554.HeartMouse
De Moura Alvorcem 2021 J Neurochem2021de Moura Alvorcem, L, Britto R, Cecatto C, Roginski AC, Rohden F, Scholl JN, Guma FCR, Figueiro F, Amaral AU, Zanatta G, Seminotti B, Wajner M, Leipnitz G. (2021) Ethylmalonic acid impairs bioenergetics by disturbing succinate and glutamate oxidation and induces mitochondrial permeability transition pore opening in rat cerebellum. J Neurochem 158(2): 262–81.Nervous systemRat
Pesta 2021 Front Endocrinol (Lausanne)2021Pesta D, Jelenik T, Zaharia OP, Bobrov P, Görgens S, Bódis K, Karusheva Y, Krako Jakovljevic N, Lalic NM, Markgraf DF, Burkart V, Müssig K, Knebel B, Kotzka J, Eckel J, Strassburger K, Szendroedi J, Roden M (2021) NDUFB6 polymorphism is associated with physical activity-mediated metabolic changes in type 2 diabetes. https://doi.org/10.3389/fendo.2021.693683Skeletal muscleMouse
Stankova 2021 Int J Mol Sci2021Staňková P, Kučera O, Peterová E, Elkalaf M, Rychtrmoc D, Melek J, Podhola M, Zubáňová V, Červinková Z (2021) Western diet decreases the liver mitochondrial oxidative flux of succinate: insight from a murine NAFLD model. https://doi.org/10.3390/ijms22136908LiverMouse
Fischer 2021 Antioxidants2021Fischer C, Volani C, Komlódi T, Seifert M, Demetz E, Valente de Souza L, Auer K, Petzer V, von Raffay L, Moser P, Gnaiger E, Weiss G (2021) Dietary iron overload and Hfe-/- related hemochromatosis alter hepatic mitochondrial function. https://doi.org/10.3390/antiox10111818LiverMouse
Hwang 2021 Crit Care2021Hwang JW, Lee MJ, Chung TN, Lee HAR, Lee JH, Choi SY, Park YJ, Kim CH, Jin I, Kim SH, Kwak HB, Heo JW, Na K, Choi S, Choi YS, Kim K (2021) The immune modulatory effects of mitochondrial transplantation on cecal slurry model in rat. Crit Care 25:20.Skeletal muscle
Liver
Kidney
Blood cells
Rat
Went 2021 MitoFit PB2021Went N, Di Marcello M, Gnaiger E (2021) Oxygen dependence of photosynthesis and light-enhanced dark respiration studied by High-Resolution PhotoRespirometry. MitoFit Preprints 2021.05. https://doi.org/10.26124/mitofit:2021-0005Algae
Brito 2021 BMC Cancer2021Brito A, Merle C, Lagarde P, Faustin B, Devin A, Lartigue L, Chibon F (2021) Cell fusion enhances energy metabolism of mesenchymal tumor hybrid cells to sustain their proliferation and invasion. BMC Cancer 21:863.FibroblastHuman
Newsom 2021 Med Sci Sports Exerc2021Newsom SA, Stierwalt HD, Ehrlicher SE, Robinson MM (2021) Substrate-specific respiration of isolated skeletal muscle mitochondria after 1 h of moderate cycling in sedentary adults. https://doi.org/10.1249/mss.0000000000002615Skeletal muscleHuman
Bastos Sant'Anna Silva 2021 Cancers (Basel)2021Bastos Sant'Anna Silva AC, Perez Valencia JA, Sciacovelli M, Lalou C, Sarlak S, Tronci L, Nikitopoulou E, Meszaros AT, Frezza C, Rossignol R, Gnaiger E, Klocker H (2021) Succinate anaplerosis has an onco-driving potential in prostate cancer cells. https://doi.org/10.3390/cancers13071727GenitalHuman
Palzur 2021 Int J Mol Sci2021Palzur E, Edelman D, Sakas R, Soustiel JF (2021) Etifoxine restores mitochondrial oxidative phosphorylation and improves cognitive recovery following traumatic brain injury. Int J Mol Sci 22:12881. doi: 10.3390/ijms222312881Nervous systemRat
Souidi 2021 Int J Mol Sci2021Souidi M, Sleiman Y, Acimovic I, Pribyl J, Charrabi A, Baecker V, Scheuermann V, Pesl M, Jelinkova S, Skladal P, Dvorak P, Lacampagne A, Rotrekl V, Meli AC (2021) Oxygen is an ambivalent factor for the differentiation of human pluripotent stem cells in cardiac 2D monolayer and 3D cardiac spheroids. Int J Mol Sci 22:E662.
Iadarola 2021 J Biol Chem2021Iadarola DM, Joshi A, Caldwell CB, Gohil VM (2021) Choline restores respiration in Psd1-deficient yeast by replenishing mitochondrial phosphatidylethanolamine. J Biol Chem 296:100539.Saccharomyces cerevisiae
Hesse 2021 FASEB J2021Hesse J, Groterath W, Owenier C, Steinhausen J, Ding Z, Steckel B, Czekelius C, Alter C, Marzoq A, Schrader J (2021) Normoxic induction of HIF-1α by adenosine-A2B R signaling in epicardial stromal cells formed after myocardial infarction. FASEB J 35:21517.Heart
Fibroblast
Rat
McKenna 2021 Redox Biol2021McKenna HT, O'Brien KA, Fernandez BO, Minnion M, Tod A, McNally BD, West JA, Griffin JL, Grocott MP, Mythen MG, Feelisch M, Murray AJ, Martin DS (2021) Divergent trajectories of cellular bioenergetics, intermediary metabolism and systemic redox status in survivors and non-survivors of critical illness. Redox Biol 41:101907.Skeletal muscleHuman
Carballal 2021 J Biol Chem2021Carballal S, Vitvitsky V, Kumar R, Hanna DA, Libiad M, Gupta A, Jones JW, Banerjee R (2021) Hydrogen sulfide stimulates lipid biogenesis from glutamine that is dependent on the mitochondrial NAD(P)H pool. J Biol Chem 297:100950.Other cell lines
Endothelial;epithelial;mesothelial cell
Human
Cretin 2021 EMBO Mol Med2021Cretin E, Lopes P, Vimont E, Tatsuta T, Langer T, Gazi A, Sachse M, Yu-Wai-Man P, Reynier P, Wai T (2021) High-throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts. EMBO Mol Med 13:13579.FibroblastMouse
Rodrigues 2021 Sci Rep2021Rodrigues AQ, Picolo VL, Goulart JT, Silva IMG, Ribeiro RB, Aguiar BA, Ferreira YB, Oliveira DM, Lucci CM, de Bem AF, Paulini F (2021) Metabolic activity in cryopreserved and grafted ovarian tissue using high-resolution respirometry. Sci Rep 11:21517.GenitalMouse
Al-Obeidallah 2021 J Pers Med2021Al-Obeidallah M, Jarkovská D, Valešová L, Horák J, Jedlička J, Nalos L, Chvojka J, Švíglerová J, Kuncová J, Beneš J, Matějovič M, Štengl M (2021) SOFA score, hemodynamics and body temperature allow early discrimination between porcine peritonitis-induced sepsis and peritonitis-induced septic shock. J Pers Med 11:164.Pig
Morgan 2021 Resuscitation2021Morgan RW, Sutton RM, Himebauch AS, Roberts AL, Landis WP, Lin Y, Starr J, Ranganathan A, Delso N, Mavroudis CD, Volk L, Slovis J, Marquez AM, Nadkarni VM, Hefti M, Berg RA, Kilbaugh TJ (2021) A randomized and blinded trial of inhaled nitric oxide in a piglet model of pediatric cardiopulmonary resuscitation. Resuscitation 162:274-83 .Nervous systemPig
Sandoval-Acuna 2021 Cancer Res2021Sandoval-Acuña C, Torrealba N, Tomkova V, Jadhav SB, Blazkova K, Merta L, Lettlova S, Adamcová MK, Rosel D, Brábek J, Neuzil J, Stursa J, Werner L, Truksa J (2021) Targeting mitochondrial iron metabolism suppresses tumor growth and metastasis by inducing mitochondrial dysfunction and mitophagy. Cancer Res 81:2289-303.
Isei 2021 Comp Biochem Physiol C Toxicol Pharmacol2021Isei MO, Chinnappareddy N, Stevens D, Kamunde C (2021) Anoxia-reoxygenation alters H2O2 efflux and sensitivity of redox centers to copper in heart mitochondria. Comp Biochem Physiol C Toxicol Pharmacol 248:109111.HeartFishes
Yoshino 2021 Science2021Yoshino M, Yoshino J, Kayser BD, Patti GJ, Franczyk MP, Mills KF, Sindelar M, Pietka T, Patterson BW, Imai SI, Klein S (2021) Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science 372:1224-29. https://doi.org/10.1126/science.abe9985Skeletal muscleHuman