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From Bioblast
 YearReferenceCouplingPathwayPreparationOrganismTissue;cell
Cunha-de 2017 Thesis2017Cunha-de Padua MM (2017) Mecanismos citotóxicos da galactomanana de sementes de Schizolobium amazonicum e seus complexos com oxovanádio em células de hepatocarcinoma humano (HepG2) e efeito do silenciamento da enzima glucose-6-fosfato isomerase (GPI) na sobrevivência de células de adenocarcinoma de cólon humano (LS174T). Doctoral Thesis p160.LEAK
ROUTINE
OXPHOS
ET
N
NS
ROX
Intact cells
Permeabilized cells
HumanLiver
Other cell lines
Chin 2017 US Patent2017Chin MT, Chien WM, Dinca A (2017) Methods for treating and preventing cardiomyopathy. US Patent WO2016094791A1.LEAK
OXPHOS
ET
N
CIV
ROX
HomogenateMouseHeart
Asseburg 2017 Thesis2017Asseburg H (2017) Untersuchungen zur nutritiven Prävention der Neurodegeneration – Wirkungen von Trauben- und Olivenpolyphenolen auf die mitochondriale und kognitive Dysfunktion bei der Gehirnalterung und Alzheimer-Erkrankung. Dissertation p296.LEAK
OXPHOS
ET
N
S
CIV
NS
ROX
Permeabilized cells
Isolated mitochondria
Intact cells
Mouse
Rat
Nervous system
Other cell lines
Selwood 2017 US Patent2017Selwood DL, Baker D, Szabadkai G, Duchen MR, Hill JM, Warne JND (2017) Quinolium conjugates of cyclosporin. US Patent US20170349632 A1.LEAK
OXPHOS
ET
N
ROX
Isolated mitochondriaMouseLiver
Comelli 2017 J Bioenerg Biomembr2017Comelli M, Pretis I, Buso A, Mavelli I (2017) Mitochondrial energy metabolism and signalling in human glioblastoma cell lines with different PTEN gene status. J Bioenerg Biomembr 50:33-52.LEAK
ROUTINE
OXPHOS
ET
N
Gp
CIV
NS
ROX
Intact cells
Permeabilized cells
HumanNervous system
Dent 2017 Mol Metab2017Dent JR, Martins VF, Svensson K, LaBarge SA, Schlenk NC, Esparza MC, Buckner EH, Meyer GA, Hamilton DL, Schenk S, Philp A (2017) Muscle-specific knockout of general control of amino acid synthesis 5 (GCN5) does not enhance basal or endurance exercise-induced mitochondrial adaptation. Mol Metab 6:1574-84.LEAK
OXPHOS
ET
F
N
S
NS
ROX
Permeabilized tissueMouseSkeletal muscle
Scheede-Bergdahl 2017 Can J Physiol Pharmacol2017Scheede-Bergdahl C, Bergdahl A (2017) Adaptation of mitochondrial expression and ATP production in dedifferentiating vascular smooth muscle cells. Can J Physiol Pharmacol 95:1473-9.LEAK
OXPHOS
F
N
CIV
NS
ROX
Permeabilized tissueMouseEndothelial;epithelial;mesothelial cell
Tueller 2017 Biochem Biophys Res Commun2017Tueller DJ, Harley JS, Hancock CR (2017) Effects of curcumin and ursolic acid on the mitochondrial coupling efficiency and hydrogen peroxide emission of intact skeletal myoblasts. Biochem Biophys Res Commun 492:368-72.LEAK
ROUTINE
OXPHOS
F
N
NS
ROX
Permeabilized cells
Intact cells
Skeletal muscle
Dechandt 2017 J Bioenerg Biomembr2017Dechandt CRP, Zuccolotto-Dos-Reis FH, Teodoro BG, Fernandes AMAP, Eberlin MN, Kettelhut IC, Curti C, Alberici LC (2017) Triacsin C reduces lipid droplet formation and induces mitochondrial biogenesis in primary rat hepatocytes. J Bioenerg Biomembr 49:399-411.LEAK
ROUTINE
ET
F
N
ROX
Permeabilized cells
Intact cells
RatLiver
Stepanova 2017 J Cereb Blood Flow Metab2017Stepanova A, Kahl A, Konrad C, Ten V, Starkov AS, Galkin A (2017) Reverse electron transfer results in a loss of flavin from mitochondrial complex I: Potential mechanism for brain ischemia-reperfusion injury. J Cereb Blood Flow Metab 37:3649-58.OXPHOS
ET
LEAK
N
NS
ROX
Isolated mitochondriaMouseNervous system
Yu 2017 Free Radic Biol Med2017Yu Y, Wang L, Delguste F, Durand A, Guilbaud A, Rousselin C, Schmidt AM, Tessier F, Boulanger E, Neviere R (2017) Advanced glycation end products receptor RAGE controls myocardial dysfunction and oxidative stress in high-fat fed mice by sustaining mitochondrial dynamics and autophagy-lysosome pathway. Free Radic Biol Med 112:397-410.LEAK
OXPHOS
F
N
CIV
ROX
Permeabilized tissueMouseHeart
De Velasco 2017 Br J Nutr2017de Velasco PC, Chicaybam G, Ramos-Filho DM, Dos Santos RMAR, Mairink C, Sardinha FLC, El-Bacha T, Galina A, Tavares-do-Carmo MDG (2017) Maternal intake of trans-unsaturated or interesterified fatty acids during pregnancy and lactation modifies mitochondrial bioenergetics in the liver of adult offspring in mice. Br J Nutr 118:41-52.LEAK
OXPHOS
ET
N
NS
ROX
Isolated mitochondriaMouseLiver
Yeh 2017 Thesis2017Yeh A (2017) Modulation of mitochondrial function as an indicator for sublethal effects of contaminants of emerging concern. Dissertation p117.LEAK
OXPHOS
ET
N
CIV
NS
ROX
Permeabilized cells
Permeabilized tissue
Human
Fishes
Liver
Rowley 2017 Thesis2017Rowley TJ (2017) The effect of cocoa flavanols on β-cell mass and function. Master's Thesis p131.OXPHOS
ET
N
NS
ROX
Permeabilized cellsRatIslet cell;pancreas;thymus
Wu 2017 Sci Rep2017Wu LH, Chang SC, Fu TC, Huang CH, Wang JS (2017) High-intensity interval training improves mitochondrial function and suppresses thrombin generation in platelets undergoing hypoxic stress. Sci Rep 7:4191.LEAK
OXPHOS
ET
ROUTINE
N
NS
ROX
CIV
Permeabilized cells
Intact cells
HumanBlood cells
Platelet
Briston 2017 Sci Rep2017Briston T, Roberts M, Lewis S, Powney B, M Staddon J, Szabadkai G, Duchen MR (2017) Mitochondrial permeability transition pore: sensitivity to opening and mechanistic dependence on substrate availability. Sci Rep 7:10492.OXPHOS
ET
N
S
NS
ROX
Isolated mitochondriaRatLiver
Lopez 2017 Sci Rep2017Lopez Sanchez MIG, Waugh HS, Tsatsanis A, Wong BX, Crowston JG, Duce JA, Trounce IA (2017) Amyloid precursor protein drives down-regulation of mitochondrial oxidative phosphorylation independent of amyloid beta. Sci Rep 7:9835.LEAK
OXPHOS
ET
N
NS
ROX
Permeabilized cellsHuman
Thomsen 2017 Neurobiol Aging2017Thomsen K, Yokota T, Hasan-Olive MM, Sherazi N, Fakouri NB, Desler C, Regnell CE, Larsen S, Rasmussen LJ, Dela F, Bergersen LH, Lauritzen M (2017) Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus. Neurobiol Aging 61:215-24.LEAK
OXPHOS
N
NS
ROX
MouseNervous system
Parajuli 2017 PLOS ONE2017Parajuli N, Shrum S, Tobacyk J, Harb A, Arthur JM, MacMillan-Crow LA (2017) Renal cold storage followed by transplantation impairs expression of key mitochondrial fission and fusion proteins. PLOS ONE 12:e0185542.OXPHOSN
S
ROX
Permeabilized tissueRatKidney
Nan 2017 Circ Res2017Nan J, Hu H, Sun Y, Zhu L, Wang Y, Zhong Z, Zhao J, Zhang N, Wang Y, Wang Y, Ye J, Zhang L, Hu X, Zhu W, Wang J (2017) TNFR2 stimulation promotes mitochondrial fusion via Stat3- and NF-kB-dependent activation of OPA1 expression. Circ Res 121:392-410.OXPHOS
ET
N
S
NS
ROX
Intact cellsMouseHeart
Permer 2017 Bachelor Thesis2017Permer M (2017) Respirometrische Charakterisierung kryopräservierter HEK 239T Zellen. Bachelor Thesis 1-56.LEAK
ROUTINE
OXPHOS
ET
F
N
S
Gp
CIV
NS
ROX
Permeabilized cells
Intact cells
HumanOther cell lines
HEK
Hu 2017 Proc Natl Acad Sci U S A2017Hu H, Nan J, Sun Y, Zhu D, Xiao C, Wang Y, Zhu L, Wu Y, Zhao J, Wu R, Chen J, Yu H, Hu X, Zhu W, Wang J (2017) Electron leak from NDUFA13 within mitochondrial complex I attenuates ischemia-reperfusion injury via dimerized STAT3. Proc Natl Acad Sci U S A 114:11908-13.OXPHOSN
S
CIV
NS
ROX
Isolated mitochondriaMouse
Krylova 2017 Biomed Khim2017Krylova TD, Tsygankova PG, Itkis YS, Sheremet NL, Nevinitsyna TA, Mikhaylova SV, Zakharova EY (2017) High resolution respirometry in diagnostic of mitochondrial disorders caused by mitochondrial complex I deficiency. Biomed Khim 63:327-33.ETN
S
NS
ROX
Permeabilized cells
Intact cells
HumanEndothelial;epithelial;mesothelial cell
Fibroblast
Lang 2017 Aging (Albany NY)2017Lang A, Anand R, Altinoluk-Hambüchen S, Ezzahoini H, Stefanski A, Iram A, Bergmann L, Urbach J, Böhler P, Hänsel J, Franke M, Stühler K, Krutmann J, Scheller J, Stork B, Reichert AS, Piekorz RP (2017) SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy. Aging (Albany NY) 9:2163-89.LEAK
ET
ROUTINE
ROXIntact cellsHumanKidney
HEK
Djordjevic 2017 Neuroscience2017Djordjevic J, Thomson E, Chowdhury SR, Snow WM, Perez C, Wong TP, Fernyhough P, Albensi BC (2017) Brain region- and sex-specific alterations in mitochondrial function and NF-κB signaling in the TgCRND8 mouse model of Alzheimer's disease. Neuroscience 361:81-92.ROUTINE
OXPHOS
ET
N
S
ROX
Isolated mitochondriaMouseNervous system
Mueller 2017 Orphanet J Rare Dis2017Mueller SM, Gehrig SM, Petersen JA, Frese S, Mihaylova V, Ligon-Auer M, Khmara N, Nuoffer JM, Schaller A, Lundby C, Toigo M, Jung HH (2017) Effects of endurance training on skeletal muscle mitochondrial function in Huntington disease patients. Orphanet J Rare Dis 12:184.LEAK
OXPHOS
ET
F
N
S
CIV
NS
ROX
Permeabilized tissueHumanSkeletal muscle
Ruiz 2017 Brain Pathol2017Ruiz M, Bégou M, Launay N, Ranea-Robles P, Bianchi P, López-Erauskin J, Morató L, Guilera C, Petit B, Vaurs-Barriere C, Guéret-Gonthier C, Bonnet-Dupeyron MN, Fourcade S, Auwerx J, Boespflug-Tanguy O, Pujol A (2017) Oxidative stress and mitochondrial dynamics malfunction are linked in Pelizaeus-Merzbacher disease. Brain Pathol 28:611-30.LEAK
ROUTINE
ET
ROXIntact cellsHuman
Mouse
Nervous system
Fibroblast
Bombaca 2017 Free Radic Biol Med2017Bombaça ACS, Dias FA, Ennes-Vidal V, Garcia-Gomes ADS, Sorgine MHF, d'Avila-Levy CM, Menna-Barreto RFS (2017) Hydrogen peroxide resistance in Strigomonas culicis: Effects on mitochondrial functionality and Aedes aegypti interaction. Free Radic Biol Med 113:255-66.ROUTINECIV
ROX
Intact cellsProtists
JanssenDuijghuijsen 2017 Front Physiol2017JanssenDuijghuijsen LM, Grefte S, de Boer VCJ, Zeper L, van Dartel DAM, van der Stelt I, Bekkenkamp-Grovenstein M, van Norren K, Wichers HJ, Keijer J (2017) Mitochondrial ATP depletion disrupts Caco-2 monolayer integrity and internalizes Claudin 7. Front Physiol 8:794.LEAK
ROUTINE
ET
ROXIntact cellsHumanEndothelial;epithelial;mesothelial cell
Other cell lines
Zholobenko 2017 PLOS ONE2017Zholobenko AV, Mouithys-Mickalad A, Dostal Z, Serteyn D, Modriansky M (2017) On the causes and consequences of the uncoupler-like effects of quercetin and dehydrosilybin in H9c2 cells. PLOS ONE 12:e0185691.LEAK
OXPHOS
ET
ROUTINE
F
N
S
NS
ROX
Permeabilized cells
Intact cells
RatHeart
Kanaan 2017 Redox Biol2017Kanaan GN, Ichim B, Gharibeh L, Maharsy W, Patten DA, Xuan JY, Reunov A, Marshall P, Veinot J, Menzies K, Nemer M, Harper ME (2017) Glutaredoxin-2 controls cardiac mitochondrial dynamics and energetics in mice, and protects against human cardiac pathologies. Redox Biol 14:509-21.LEAK
OXPHOS
N
CIV
NS
ROX
Permeabilized tissueMouseHeart
Santos 2017 Sci Rep2017Santos GC, Zeidler JD, Pérez-Valencia JA, Sant'Anna-Silva ACB, Da Poian AT, El-Bacha T, Almeida FCL (2017) Metabolomic analysis reveals vitamin D-induced decrease in polyol pathway and subtle modulation of glycolysis in HEK293T cells. Sci Rep 7:9510.LEAK
ET
ROXHumanKidney
HEK
White 2017 Sci Rep2017White SH, Warren LK, Li C, Wohlgemuth SE (2017) Submaximal exercise training improves mitochondrial efficiency in the gluteus medius but not in the triceps brachii of young equine athletes. Sci Rep 7:14389.LEAK
OXPHOS
ET
N
NS
ROX
Permeabilized tissueHorseSkeletal muscle
MiPNet21.14 Reference sample HRR2016-10-19
O2k-Protocols

Development of a reference sample for HRR.

LEAK
ROUTINE
OXPHOS
ET
F
N
S
Gp
CIV
NS
Other combinations
ROX
Intact cells
Permeabilized cells
HumanHEK
MiPNet21.12 Comparison mt respiration media2016-10-18
O2k-Protocols

O2k-MultiSensor: Mitochondrial respiration media for HRR and simultaneous O2k-Fluorometry.

LEAK
ROUTINE
OXPHOS
ET
N
S
NS
ROX
Intact cells
Permeabilized cells
HumanHEK
MiPNet21.13 Comparison mt-preparations2016-10-18
O2k-Protocols

O2k-Protocols: Mitochondrial preparations for HRR.

LEAK
OXPHOS
ET
N
S
NS
ROX
Permeabilized cells
Homogenate
Isolated mitochondria
MouseHeart
MiPNet10.04 CellRespiration2016-08-08
O2k-Protocols

An experiment with high-resolution respirometry: coupling control in cell respiration.

LEAK
ROUTINE
ET
ROXIntact cellsMouseBlood cells
MiPNet21.07 MitoFit DatLab PT2016-07-20
O2k-Protocols

MitoFit DatLab proficiency test.

LEAK
OXPHOS
ET
F
N
S
Gp
CIV
Other combinations
ROX
Permeabilized cellsHuman
Jang 2016 J Intensive Care Med2016Jang DH, Greenwood JC, Spyres MB, Eckmann D (2016) Measurement of mitochondrial respiration and motility in acute care: sepsis, trauma, and poisoning. J Intensive Care Med 32:86-94.LEAK
ROUTINE
ET
ROXIntact cellsHumanBlood cells
Lymphocyte
Barth 2016 Thesis2016Barth C (2016) Effekte einer intermittierenden Hyperoxie auf die mitochondriale Atmung in Alveolarmakrophagen. Dissertation p69.LEAK
ROUTINE
OXPHOS
N
S
CIV
NS
ROX
Permeabilized cells
Intact cells
MouseLung;gill
Macrophage-derived
Dias 2016 Neurobiol Aging2016Dias C, Lourenço CF, Ferreiro E, Barbosa RM, Laranjinha J, Ledo A (2016) Age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications for neurometabolic regulation. Neurobiol Aging 46:84-95.LEAK
ET
N
S
ROX
Permeabilized tissueMouseNervous system
Jiroutkova 2016 JPEN J Parenter Enteral Nutr2016Jiroutková K, Krajčová A, Žiak J, Fric M, Gojda J, Džupa V, Kalous M, Tůmová J, Trnka J, Duška F (2016) Mitochondrial function in an in vitro model of skeletal muscle of patients with protracted critical illness and intensive care unit-acquired weakness. JPEN J Parenter Enteral Nutr 41:1213-21.LEAK
ET
F
ROX
HumanSkeletal muscle
Other cell lines
Price 2016 J Thermal Biol2016Price ER, Sirsat TS, Sirsat SKG, Kang G, Keereetaweep J, Aziz M, Chapman KD, Dzialowski EM (2016) Thermal acclimation in American alligators: Effects of temperature regime on growth rate, mitochondrial function, and membrane composition. J Thermal Biol p11.LEAK
OXPHOS
ET
N
S
CIV
NS
ROX
Permeabilized tissueReptilesHeart
Skeletal muscle
Lemieux 2016 Mitochondrion2016Lemieux H, Boemer F, van Galen G, Serteyn D, Amory H, Baise E, Cassart D, van Loon G, Marcillaud-Pitel C, Votion DM (2016) Mitochondrial function is altered in horse atypical myopathy. Mitochondrion 30:35-41.OXPHOS
ET
N
S
NS
ROX
Permeabilized tissueHorseSkeletal muscle
Kimball 2016 Thesis2016Kimball RL (2016) The role of hypoxia on pyruvate kinase M2, mammalian target of rapamycin, mitochondrial function, and cell invasion in the trophoblast. Master Thesis p55.LEAK
OXPHOS
ET
N
S
NS
ROX
Permeabilized cellsHumanGenital
Other cell lines
Gregg 2016 Diabetes2016Gregg T, Poudel C, Schmidt BA, Dhillon RS, Sdao SM, Truchan NA, Baar EL, Fernandez LA, Denu JM, Eliceiri KW, Rogers JD, Kimple ME, Lamming DW, Merrins MJ (2016) Pancreatic β cells from mice offset age-associated mitochondrial deficiency with reduced KATP channel activity. Diabetes 65:2700-10.LEAK
OXPHOS
ET
N
S
NS
ROX
Permeabilized tissueHuman
Mouse
Islet cell;pancreas;thymus
Other cell lines
Camacho-Pereira 2016 Cell Metab2016Camacho-Pereira J, Tarragó MG, Chini CC, Nin V, Escande C, Warner GM, Puranik AS, Schoon RA, Reid JM, Galina A, Chini EN (2016) CD38 dictates age-related NAD decline and mitochondrial dysfunction through an SIRT3-dependent mechanism. Cell Metab 23:1127-39.LEAK
ROUTINE
OXPHOS
ET
S
ROX
Isolated mitochondria
Intact cells
Human
Mouse
Liver
Lung;gill
Other cell lines
Ryan 2016 Diabetes2016Ryan TE, Schmidt CA, Green TD, Spangenburg EE, Neufer PD, McClung JM (2016) Targeted expression of catalase to mitochondria protects against ischemic myopathy in high fat fed mice. Diabetes 65:2553-68.LEAK
OXPHOS
ET
N
S
CIV
Other combinations
ROX
Isolated mitochondriaMouseSkeletal muscle
Franko 2016 Diabetes2016Franko A, Huypens P, Neschen S, Irmler M, Rozman J, Rathkolb B, Neff F, Prehn C, Dubois G, Baumann M, Massinger R, Gradinger D, Przemeck GK, Repp B, Aichler M, Feuchtinger A, Schommers P, Stöhr O, Sanchez-Lasheras C, Adamski J, Peter A, Prokisch H, Beckers J, Walch AK, Fuchs H, Wolf E, Schubert M, Wiesner RJ, Hrabě de Angelis M (2016) Bezafibrate improves insulin sensitivity and metabolic flexibility in STZ-treated diabetic mice. Diabetes 65:2540-52.LEAK
OXPHOS
N
S
CIV
ROX
Permeabilized cells
Permeabilized tissue
HumanSkeletal muscle
Fibroblast
Christensen 2016 J Appl Physiol (1985)2016Christensen PM, Jacobs RA, Bonne T, Flück D, Bangsbo J, Lundby C (2016) A short period of high-intensity interval training improves skeletal muscle mitochondrial function and pulmonary oxygen uptake kinetics. J Appl Physiol (1985) 120:1319-27.LEAK
OXPHOS
ET
F
N
S
CIV
NS
Other combinations
ROX
Permeabilized tissueHumanSkeletal muscle
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