Difference between revisions of "Sauer 1980 J Biol Chem"

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Sauer LA, Dauchy RT, Nagel WO, Morris HP (1980) Mitochondrial malic enzymes. Mitochondrial NAD(P)+-dependent malic enzyme activity and malate-dependent pyruvate formation are progression-linked in Morris hepatomas. J Biol Chem 255: 3844-8.

» PMID: 7372652 Open Access

Sauer LA, Dauchy RT, Nagel WO, Morris HP (1980) J Biol Chem

Abstract:

In the presence of ADP, pyruvate formed from malate was rapidly oxidized to CO2 by pyruvate dehydrogenase. The production and oxidation of pyruvate occurred entirely within the mitochondrial matrix space. The results are consistent with a role for the NAD(P)⁺-dependent malic enzyme in net glutamine oxidation in undifferentiated hepatomas.

Labels: MiParea: Respiration Pathology: Cancer

Organism: Rat Tissue;cell: Liver Preparation: Isolated mitochondria

Coupling state: OXPHOS

Malic enzyme

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 {{Publication
 |title=Sauer LA, Dauchy RT, Nagel WO, Morris HP (1980) Mitochondrial malic enzymes. Mitochondrial NAD(P)+-dependent malic enzyme activity and malate-dependent pyruvate formation are progression-linked in Morris hepatomas. J Biol Chem 255: 3844-8.
 |info=[http://www.ncbi.nlm.nih.gov/pubmed/7372652 PMID: 7372652 Open Access]
 |authors=Sauer LA, Dauchy RT, Nagel WO, Morris HP
@@ Line 11: / Line 11: @@
 |organism=Rat
 |tissues=Liver
-|preparations=Isolated Mitochondria
+|preparations=Isolated mitochondria
 |diseases=Cancer
 |couplingstates=OXPHOS
 |additional=Malic enzyme
 }}