- high-resolution terminology - matching measurements at high-resolution
NS e-input
Description
NS e-input (CI&II e-input) is electron input from a combination of N and S substrates through Complexes CI and CII simultaneously into the Q-junction corresponding to TCA cycle function in vivo, with convergent electron flow through the ETS. In mt-preparations, NS e-input requires addition not only of N (CI-linked) substrate (pyruvate&malate or glutamate&malate), but of S (succinate) simultaneously, since metabolite depletion in the absence of succinate prevents a significant stimulation of S-linked respiration. For more details, see: Additive effect of convergent electron flow.
Abbreviation: NS, CI&II
Reference: Gnaiger 2014 MitoPathways, Gnaiger 2009 Int J Biochem Cell Biol
MitoPedia concepts:
Respiratory state,
SUIT state
