Difference between revisions of "MitoCom Events"
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Revision as of 16:39, 3 May 2013
MitoCom News
Xtreme Everst 2 - high-altitude research in Nepal
Dr. Erich Gnaiger and Verena Laner participated at the Xtreme Everest 2 Expedition in Nepal.
Erich Gnaiger (Innsbruck, AT) joined the Xtreme Everest 2 mitochondrial team at Everest Base Camp (5,300 m) where acclimation to high altitude was studied using three O2k (March to May 2013). In Kathmandu (Nepal) at low altitude (1,400 m), Andrew Murray (Cambridge, UK) operated high-resolution respirometry on human musle biopsies with assistance by Verena Laner (Innsbruck, AT).
More infomation: Xtreme Everest 2
Some impressions of the Expedition:
The participants from Innsbruck are supported by the K-Regio project MitoCom Tyrol, D. Swarovski Research Laboratory (Medical University of Innsbruck), and OROBOROS INSTRUMENTS.
MitoCom Track Record 2012
O2k-Workshop, Schroecken, Austria, Dec 5 - 10
Bioblast 2012 - Conference on Mitochondrial Competence
The Bioblast Conference 2012 took place in Hotel Grauer Bär from 10th to 12th December 2012. With more than 70 participants from 19 nations the conference was a great success.
For the article of the Medical University Innsbruck, see: MUI website
More information: Bioblast 2012
Padua Muscle Days, Nov 23 - 25
After the satellite meeting in Vienna on October 17th, Prof. Dr. Gnaiger was invited by Prof. Dr. Ugo Carraro (University of Padua) to Padua for a talk on high-resolution respirometry in permeabilized fibers from small biopsies of human muscle.
MCI Forum Technologie & Life Sciences, Innsbruck, Nov 6
In her talk, Mag. Verena Laner will outline the development of the company OROBOROS INSTRUMENTS and will walk you through the early company days up to the current K-Regio Project MitoCom Tyrol. Programme
Satellite Meeting Vienna, Oct 17
Dr. Erich Gnaiger participated at the Satellite Meeting in Vienna, which took place on 17th October.
Attendees of this meeting were Delegates of the University in Padua (Univ.-Prof. Dr. Ugo Carraro and Dr. Sandra Zampieri), University in Chieti (Univ.-Prof. Dr. Protasi) and University in Rome (Univ.-Prof. Dr. Andrea Musaro).
The meeting was organized by Dr. Kern from the Ludwig Boltzmann Institute in Vienna.
Standort Lunch Vienna, 2012 Sep 27
Dr. Erich Gnaiger presented the MitoCom project at the Standort Lunch in Vienna, organized by the Standortagentur Tirol. More information.
The article of the STANDORT Tirol you can find in issue no. 15, page 8
Medizintechnikforum Hall, 2012 Sep 20 to 21
OROBOROS INSTRUMENTS exhibited at the Medizintechnikforum Hall, showing latest developments in high-resolution respirometry in combination with the O2k-Fluorescence LED2-Module. MitoCom Tyrol was presented together with the Open Innovation project, both supported by the Government of Tyrol.
Tiroltag, Europäisches Forum Alpbach, 2012 Aug 19
Verena Laner, the project manager of MitoCom Tyrol, took part at the Tirolday, which was the "Opening" of the European Congress in Alpbach 2012. The main topic was "The future of sports in the Alps", which is an integral part of the MitoCom project. Additionally to the presentations and the award presentation ceremony for young scientists, there was a podium discussion with well-known experts such as the famous alpinist Reinhard Messner.
MitoCom Cooperation AltitudeOmics 2012, 2012 July 20 to Aug 13
Dr. Erich Gnaiger participated in the AltitudeOmics2012 project in Bolivia and provided the scientists with two O2ks and his expertise. Aim of the study was to investigate the impacts of hypoxia/acclimatization onto molecular mechanisms of the human cells.
Visiting scientist: Prof. Dr. Fr. Baby Joseph, July 19
On July 19th, Prof. Dr. Fr. Baby Joseph visited the OROBOROS office.
Time schedule of the research visit
Houska Award 2011 - First price for MitoCom Tyrol, April 26
- First price - Medical University of Innsbruck: http://www.oroboros.at/?Houska-Award_2011
- http://www.houskapreis.at/siegerprojekt-2011-licht-in-die-kraftwerke-der-zellen
- http://www.houskapreis.at
- http://www.tt.com/Nachrichten/4702341-6/houska-preise-an-universit%C3%A4ten-in-innsbruck-und-graz.csp
Mitolab O2k-Fluorometry Workshop Madrid, Spain, May 7
- Mitolab Workshop by Erich Gnaiger
- Contact: Eduardo Rial (Email: [email protected]) and Susana Cadenas (Email: [email protected])
>> See also MitoCom_Tyrol - Report
O2k-Workshop Schröcken, Austria, April 11 to 16
O2k-Workshop Sydney, Australia, April 2 to 4
First O2k-Fluorometry Workshop, Innsbruck, March 15 to 16
- IOC66 O2k-Fluorometry Workshop. An International O2k-Workshop of MitoCom Tyrol.
Manuscript accepted for publication in PloS One, March 9
- "Physical fitness and mitochondrial respiratory capacity in horse skeletal muscle" (by Votion DM, Gnaiger E, Lemieux H, Mouithys-Mickalad A, Serteyn D) was accepted for publication in PloS One.
- From the anonymous referee's comments:
- Reviewer #1: "This is an original work performed with state of the art methodologies, as high-resolution respirometry. The results indicate that not only mitochondrial capacity is a limiting factor of horse performance but also the modalities of energy substrate utilization. Horse is an animal of choice for energetic studies since it shows a huge consumption of oxygen during muscle contraction, suggesting an positive adaptation of the mitochondrial system as compared to other animals. .. This article provides new findings on the link between mitochondrial capacity and whole animal body size and aerobic capacity. It also clarifies whether mitochondrial capacity is a controling factor for horse performance. An important finding is also that the control by the phosphorylation system is stable and does not vary with the performance of the horse. In contrast, the relative utilization of complex I versus complex II varies witht he performance, and this is a new finding which adds up to our knowledge of energy regulation. This work is of broad interest for sport physiology, metabolic researchers and aging research."
- Reviewer #2: "The results could be described in a much easier way if utilizing classical definitions of mitochondrial respiratory parameters (from the late Britton Chance's milestones), such as state IV (or II), state III, uncoupled respiration, respiratory control ratio and so on." (Comment: Glossary: Respiratory states)
MitoCom Track Record 2011
- See also: Science Calendar
2011-11-29: 9. Tiroler Innovationstag
- 13:00-14:30 Cluster-Partnertreffen LIFE SCIENCES Tirol
- Programm
- ab 12.30 Uhr: Treffen im Congress Innsbruck, 3. Stock
- 13.00 Uhr: Begrüßung DDr. Petra Stöckl (Programm Managerin Life Sciences Tirol)
- 13.05 Uhr: Die neue Clusterstrategie. Vorstellung der Eckdaten
- 13.20 Uhr: Vorstellung der Clusterpartner und Diskussion der Clusterstrategie
- 14.15 Uhr Vorstellung K-Regio MitoCom. Univ.-Prof. Dr. Erich Gnaiger (Oroboros)
- 15:00 m Tiroler Innovationstag - Programm
2011-11-19: An extension of MitoPedia
- In addition to the List of respirometry terms, the List of fluorometry terms and List of spectrophotometry terms were initiated by David Harrison.
2011-11-11: Bioblast alert
- Bioblast alert was launched, for information purposes, not intended to be an advertisement.
2011-11-04: Product news
2011-November: MitoCom Lectures, Innsbruck
2011-10-20 to 21: Targeting Mitochondria, Berlin, DE
- Invited lecture: Erich Gnaiger - Gnaiger 2011 Abstract-Berlin
- Exhibition of OROBOROS INSTRUMENTS and MitoCom Tyrol: Katrin Stecher, Lyda Staudacher
2011-09-24: High-output to replace wasteful high-throughput?
2011-09-05 to 04: MiP2011 Bordeaux, France
- 8th Conference on Mitochondrial Physiology - MiP2011. Bordeaux, France.
- Invited lecture: Erich Gnaiger - Sumbalova 2011 Abstract Bordeaux
- Poster: Erich Gnaiger - Lemieux_2011_Abstract Bordeaux
- Poster: Mario Fasching - Fasching_2011_Abstract Bordeaux
- Exhibition of OROBOROS INSTRUMENTS and MitoCom Tyrol: Katrin Stecher, Lyda Staudacher
2011-08-31 to 09-04: KAGOSHIMA JAPAN
- 5th Biennial Meeting of Society for Free Radical Research (SFRR)-Asia, 8th Conference of Asian Society for Mitochondrial Research and Medicine (ASMRM), and 11th Conference of Japanese Society of Mitochondrial Research and Medicine (J-mit); Kagoshima Citizens´Culture Hall, Kagoshima, Japan. Chair: Prof. Hideyuki J. Majima; E-mail: [email protected]
- Invited lecture: Erich Gnaiger - Sumbalova 2011 Abstract Kagoshima
- Exhibition of the OROBOROS Oxygraph-2k: Yoshiaki Nakayoshi, Sanyo Trading Co. Ltd., Tokyo, JP
2011-08-26 to 27: O2k-Workshop China
2011-08-12: Circular on MitoScore
MitoScore is an initiative of MitoCom:
2011-08-09: Manuscript accepted for publication in IJBCB
- "Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart" (by Lemieux H, Semsroth S, Antretter H, Höfer D, Gnaiger E) was accepted for publication in Intl. J. Biochem. Cell Biol.
- From the anonymous referee's comments:
- Reviewer #1: "The manuscript by Lemieux and colleagues offers interesting insight into the bioenergetics of early phases of heart failure."
- Reviewer #2: "This is a beautifully written work, replete with well-designed experiments and, within the space limitations, a nice review of the pertinent literature. The demonstration of impaired mitochondrial fatty acid oxidation in early stages of human failure is very important, as is the demonstration of defects in the phosphorylation system and Complex I-linked respiration."
- Reviewer #3: "The manuscript belongs literally to the symphony of bioenergetics and have mastered on a maximum thorough and detailed level a priority study of human heart disease bioenergetics in an intermediate state of heart disease, which was done only scarcely in medical sciences and for this orthodox approach this work deserves a high attention. It elegantly describes detailed oxidative phosphorylation parameters in heart disease compared to the control human heart. Using high-resolution respirometry of permeabilized human heart muscle fibres authors progressively describe distinct aspect of measured data in logical steps to present important differences of diminished mitochondrial function during heart failure. Using elegant protocols developed for years, authors distinguish between phosphorylating (OXPHOS) and non-phosphorylating (ETS) conditions with both complex I and II input using physiological substrates of glucose and lipid oxidation. With presented protocols, authors are able to provide conclusions regarding, e.g., complex I impairment, phosphorylation system limitation (3.2) mitochondrial content (3.3), leak respiration involvement, etc., besides OXPHOS and ETS capacities. Authors use their own terminology describing respiratory states. It would be useful to explain briefly their terminology also in terms of the canonical state 2 - 4 terminology. In spite of this, the methodology approach and presented data are well explained."
2011-07-18: Informal MitoCom-MiPArt 18:18
- Monday, July 18 ● 18:18 h ● Schöpfstr. 18 – we thank our guests for sharing a friendly 18:18 evening with us.
- Informal get-together at 'Oroboros' - science and art - celebrate a "beautifully written work" - a "symphony of bioenergetics" (see 2011-08-09).
- Celebrate the official acceptance of K-Regio MitoCom Tyrol.
- Explore future perspectives.
2011-07-12: The K-Regio MitoCom project - accepted
- The project application MitoCom Tyrol was officially accepted.
2011-07-12: Manuscript accepted in AJP
- "Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans" by Pesta D, Hoppel F, Macek C, Messner H, Faulhaber M, Kobel C, Parson W, Burtscher M, Schocke M, Gnaiger E, was accepted for publication in Am. J. Physiol. Regul. Integr. Comp. Physiol. (http://www.ncbi.nlm.nih.gov/pubmed/21775647).
- From the anonymous referee's comments: This is really a superb revision; the MS has been improved substantially, particularly with reference to the theory and methods re: the HRR.
2011-07-11 to 13: Introductory O2k-Workshop (IOC62) - MitoCom Tyrol
- Location: OROBOROS INSTRUMENTS, Schöpfstr. 18, Innsbruck, Austria.
- More informatio: IOC62
2011-06-15 to 18: UMDF Mitochondrial Medicine 2011 - Chicago, US
- Poster: Erich Gnaiger - Burtscher 2011 AbstractUMDFChicago
- Poster: Dominik Pesta - Pesta_2011_AbstractUMDFChicago-Training
- Poster: Dominik Pesta - Pesta_2011_AbstractUMDFChicago-Diagnosis
- Exhibition of OROBOROS INSTRUMENTS and MitoCom Tyrol: Katrin Stecher, Dominik Pesta, Erich Gnaiger
2011-05-18: MiPArt - Mitochondria - the Aliens in our Cells
MiPArt - Mitochondria - the Aliens in our Cells
- Exhibition (Odra Noel, Richard Altmann and others)
- Presentation of MitoCom Tyrol
