Difference between revisions of "Carnitine palmitoyltransferase I"
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|description=CPT | |description='''Carnitine palmitoyltransferase I''' (CPT 1) is a regulatory enzyme in mitochondrial long-chain acyl-CoA uptake and further oxidation. CPT 1 is associated with the outer mt-membrane and catalyses the formation of acylcarnitines from acyl-CoA and L-carnitine. There are three enzyme isoforms: CPT 1A (liver type), CPT 1B (muscle type), CPT 1C (brain type). Isoforms have significantly different kinetic and regulatory properties. Malonyl-CoA is an endogenous inhibitor of CPT 1. | ||
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|mitopedia topic= | |mitopedia topic=Enzyme | ||
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Revision as of 18:09, 2 October 2014
- high-resolution terminology - matching measurements at high-resolution
Carnitine palmitoyltransferase I
Description
Carnitine palmitoyltransferase I (CPT 1) is a regulatory enzyme in mitochondrial long-chain acyl-CoA uptake and further oxidation. CPT 1 is associated with the outer mt-membrane and catalyses the formation of acylcarnitines from acyl-CoA and L-carnitine. There are three enzyme isoforms: CPT 1A (liver type), CPT 1B (muscle type), CPT 1C (brain type). Isoforms have significantly different kinetic and regulatory properties. Malonyl-CoA is an endogenous inhibitor of CPT 1.
Abbreviation: CPT 1
MitoPedia topics: Enzyme
