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CH Lausanne Canto C

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CH Lausanne Canto C

Oroboros O2k-Network

O2k-Network
O2k-Network Lab Nestl茅 Institute of Health Sciences SA

Campus EPFL

Power-O2k Network Cluster: CH Lausanne EPFL

Address Quartier de l'innovation

B芒timent G, 1015

City Lausanne
State/Prov
Country Switzerland
Weblink
Contact Canto Alvarez Carlos
Team Baetge Edward, Feige Jerome, Weiderkehr Andreas
Team previous
Status 4 Power-O2k 2012-
Oroboros Events IOC97
Topics Nutrient sensing, energy sensing and metabolic adaptation


O2k-Publications

 PublishedReference
Valera-Alberni 2021 Cell Rep2021Valera-Alberni M, Joffraud M, Miro-Blanch J, Capellades J, Junza A, Dayon L, N煤帽ez Galindo A, Sanchez-Garcia JL, Valsesia A, Cercillieux A, S枚llner F, Ladurner AG, Yanes O, Cant贸 C (2021) Crosstalk between Drp1 phosphorylation sites during mitochondrial remodeling and their impact on metabolic adaptation. Cell Rep 36:109565.
Ling 2019 Am J Clin Nutr2019Ling Y, Carayol J, Galusca B, Canto C, Montaurier C, Matone A, Vassallo I, Minehira K, Alexandre V, Cominetti O, N煤帽ez Galindo A, Corth茅sy J, Dayon L, Charpagne A, M茅tairon S, Raymond F, Descombes P, Casteillo F, Peoc'h M, Palaghiu R, F茅asson L, Boirie Y, Estour B, Hager J, Germain N, Gheldof N (2019) Persistent low body weight in humans is associated with higher mitochondrial activity in white adipose tissue. Am J Clin Nutr 110:605-16.
Sambeat 2019 Nat Commun2019Sambeat A, Ratajczak J, Joffraud M, Sanchez-Garcia JL, Giner MP, Valsesia A, Giroud-Gerbetant J, Valera-Alberni M, Cercillieux A, Boutant M, Kulkarni SS, Moco S, Canto C (2019) Endogenous nicotinamide riboside metabolism protects against diet-induced liver damage. Nat Commun 10:4291.
Hollis 2018 Neuropharmacology2018Hollis F, Mitchell ES, Canto C, Wang D, Sandi C (2018) Medium chain triglyceride diet reduces anxiety-like behaviors and enhances social competitiveness in rats. Neuropharmacology 138:245-56.
Van der Kooij 2018 Mol Psychiatry2018van der Kooij MA, Hollis F, Lozano L, Zalachoras I, Abad S, Zanoletti O, Grosse J, Guillot de Suduiraut I, Canto C, Sandi C (2018) Diazepam actions in the VTA enhance social dominance and mitochondrial function in the nucleus accumbens by activation of dopamine D1 receptors. Mol Psychiatry 23:569-78.
Boutant 2017 EMBO J2017Boutant M, Kulkarni SS, Joffraud M, Ratajczak J, Valera-Alberni M, Combe R, Zorzano A, Cant贸 C (2017) Mfn2 is critical for brown adipose tissue thermogenic function. EMBO J 36:1543-58.
Greggio 2017 Cell Metab2017Greggio C, Jha P, Kulkarni SS, Lagarrigue S, Broskey NT, Boutant M, Wang X, Alonso SC, Ofori E, Auwerx J, Cant贸 C, Amati F (2017) Enhanced respiratory chain supercomplex formation in response to exercise in human skeletal muscle. Cell Metab 25:301-11.
Gariani 2016 Hepatology2016Gariani K, Menzies KJ, Ryu D, Wegner CJ, Wang X, Ropelle ER, Moullan N, Zhang H, Perino A, Lemos V, Kim B, Park YK, Piersigilli A, Pham TX, Yang Y, Ku SC, Koo SI, Fomitchova A, Cant贸 C, Schoonjans K, Sauve AA, Lee JY, Auwerx J (2016) Eliciting the mitochondrial unfolded protein response via NAD+ repletion reverses fatty liver disease. Hepatology 63:1190-204.
Boutant 2016 Cell Rep2016Boutant M, Kulkarni SS, Joffraud M, Raymond F, M茅tairon S, Descombes P, Cant贸 C (2016) SIRT1 gain of function does not mimic or enhance the adaptations to intermittent fasting. Cell Rep 14:2068-75.
Canto 2015 Curr Protoc Mouse Biol2015Cant贸 C, Garcia-Roves PM (2015) High-resolution respirometry for mitochondrial characterization of ex vivo mouse tissues. Curr Protoc Mouse Biol 5:135-53.
Hollis 2015 Proc Natl Acad Sci U S A2015Hollis F, van der Kooij MA, Zanoletti O, Lozano L, Cant贸 C, Sandi C (2015) Mitochondrial function in the brain links anxiety with social subordination. Proc Natl Acad Sci U S A 112:15486-91.
Boutant 2014 Mol Metab2014Boutant M, Joffraud M, Kulkarni SS, Garcia-Casarrubios E, Garcia-Roves PM, Ratajczak J, Fernandez-Marcos PJ, Valverde AM, Serrano M, Canto C (2014) SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function. Mol Metab 4:118-31.

O2k-Abstracts

update please


O2k-Feedback
  • We are so happy with the performance of our two Oroboros machines that we are considering buying a couple more. We tested permeabilized muscle fibers and liver samples, always obtaining an excellent performance. The resolution of the machines goes largely beyond my most optimistic expectations and, so far, I am very positively impressed with their accuracy and experimental possibilities! - Carlos Canto (2012)