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Difference between revisions of "Bioblast"

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[[File:Bioblast wiki.jpg|940px|link=http://www.bioblast.at/index.php/Bioblast|Bioblasts - Richard Altmann and MiPArt by Odra Noel]]
[[File:Bioblast wiki.jpg|940px|link=http://www.bioblast.at/index.php/Bioblast|Bioblasts - Richard Altmann and MiPArt by Odra Noel]]
{{Bioblast navigation line}}
{{Bioblast navigation line}}
[[Image:BB-Bioblast-text.jpg|left|140px|link=http://www.bioblast.at/index.php/Bioblast|Bioblast wiki]]
[[Image:BB-Bioblast-text.jpg|left|140px|Bioblast wiki]]


<div style="font-size:15px;font-weight:bold;;color:#005199;padding:5px;border-bottom:1px solid #aaaaaa;text-align:left;margin:0px;">
<div style="font-size:15px;font-weight:bold;;color:#005199;padding:5px;border-bottom:1px solid #aaaaaa;text-align:left;margin:0px;">


<big><big><big><big><big>'''[[Bioblast]]'''</big></big></big></big></big>
<big><big><big><big><big>'''[[Bioblast]]'''</big></big></big></big></big> - The '''''mt-information synthase''''' for MitoPedia, MitoFit, and more.
 
:::::: '''Bioblast Boost''' - in the spirit of [http://www.bioblast.at/index.php/Gentle_Science Gentle Science]: '''>600,000 times'''
:::: The '''''mt-information synthase''''' for MitoPedia, MitoFit, and more
:::::: '''[[Bioblast:About]]'''
:::: '''Bioblast Boost''' - in the spirit of Gentle Science
</div>
</div>
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****: [[MITOEAGLE |»MITOEAGLE today]]


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<big><big>
=== [[Bioblast alert]] 2017(01): 2017-02-03 ===
=== [[Bioblast alert]] 2016(01): 2016-02-10 ===
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[[Image:Gentle-Science_Ganesha.jpg|left|60px|link=http://www.bioblast.at/index.php/Gentle_Science|Gentle Science]]
:::: {{Template:MitoGlobal first}}


[[Image:MitoPedia.jpg|left|140px|link=http://www.bioblast.at/index.php/MitoPedia|MitoPedia]]  
::::» [[Gentle_Science#Preprints_for_Gentle_Science |'''Preprints for Gentle Science''']] - ''Scientists take pride in their work and will be guided by their own internal standards in deciding when their work is ready to be released to the community. .. the paper can receive input from more than two or three referees, which could help authors correct flawed experiments/statements and help produce a better final product published in the journal. .. Journals then may be incentivized to '''look more toward quality than speed''' and seek to publish the definitive work that will stand the test of time ..'' - Quoted from [[Vale 2015 Proc Natl Acad Sci U S A |Vale 2015]].
<br />
[[Image:MitoPedia.jpg|left|60px|link=http://www.bioblast.at/index.php/MitoPedia|MitoPedia]]  
:::: '''[[MitoPedia: SUIT]] - first steps towards a data bank of SUIT protocols'''


:::: '''Updated terminology with SUIT protocols - open for discussion:''' [[Lemieux 2017 bioRxiv |Lemieux H, Blier PU, Gnaiger E (2017) Remodeling mitochondrial pathway control of oxidative phosphorylation by temperature in the heart. bioRxiv doi: https://doi.org/10.1101/103457]].
<br />
[[Image:MITOEAGLE-logo.jpg|left|60px|link=http://www.mitoglobal.org/index.php/MITOEAGLE|COST Action MITOEAGLE]]
::::* '''2017-Mar-21 to 23''' [http://www.bioblast.at/index.php/MITOEAGLE_Barcelona_2017 Barcelona ES: Mitochondrial mapping MC meeting and workshops COST Action MITOEAGLE]


Dear colleagues:
<br /><br />
Over the past years, there was a continuous struggle towards a language for translating experimental findings obtained from [[SUIT protocols]] into shared information.
<br /><br />
Let's face it: even the state-of-the-art terminology and the many inconsistent variations are not commonly understandable - they do not make sense. Various efforts, including serial editions of ‘MitoPathways’ ([[Gnaiger 2014 MitoPathways |The Blue Book]]), were helpful but are still a failure: We cannot expect an audience to grasp our message, if we say ‘Complex I’ – when actually having in mind the pathway from NADH-linked substrates to CI - CIII - CIV. Should we rather say CI-CIII-CIV-linked ???
<br /><br />


An even worse mistake: we say ‘[[Complex I&II-linked substrate state |CI<small>&</small>II]]’ (or a previous mistake: ‘CI+II’: ''are the two enzyme complexes added?''), when we actually measure electron transfer linked to CI<small>&</small>II - CIII - CIV !!!
:::: With best wishes and kind regards,
<br /><br />


The cartoons are clear: [[Respiratory complexes]]. The words are not.
:::: [[Gnaiger E |Erich]]
<br /><br />
:::: Bioblast Chief Editor
 
I invite you to challenge fundamentally the way we think and talk and write about our results. Canning the CI-linked, CII-linked, CI<small>&</small>II (CI+II) terminology is not trivial. It is a necessary step. We and many colleagues do not readily make a real change. This change is not only important but necessary in order to render the field of mitochondrial physiology less confusing and make it more attractive. Perhaps we can even attain a deeper understanding among the involved specialists - the Bioblasts.
<br /><br />
 
'''Don't say ‘Complex I’ when it IS NOT JUST Complex I'''. Why talk about a subset or even a single '''enzyme Complex''' when we have '''complicated pathways''' in mind, fuelled by selections and combinations of '''substrate types'''. Stop for a moment. If you agree, take a glance at new entries into MitoPedia prepared during the past months.
<br />
<br />
:» [[Substrate types |Substrate types and pathway types]]<br />
|}
:» [[Categories of SUIT protocols]]<br />
:» [[SUIT protocol names]]<br />
<br />
<br />


I am looking forward to your feedback. Your input will be essential in developing a common language for communication with the people whom we want to reach with research on mitochondrial physiology. Join a new '''quality management of reporting on mitochondrial respiratory control''' to forge results into useful knowlege. Messages of mitochondrial physiology deserve to be understood on a global scale, in support of established health systems in general and mitochondrial organizations in particular. Lets cooperate in an effort to encourage our modern society to become and stay [[MitoFit]].
</big><br />


With best wishes and kind regards,
{| class="wikitable" border="1"
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<big><big>
[[File:MITOEAGLE-representation.jpg|right|250px|link=MITOEAGLE|COST Action MITOEAGLE]]
[[File:COST Logo.jpg|250px|link=MITOEAGLE|right]]
=== COST Action CA15203 MITOEAGLE ===
:::: The objective of the MITOEAGLE network is to improve our knowledge on mitochondrial function in health and disease related to '''E'''volution, '''A'''ge, '''G'''ender, '''L'''ifestyle and '''E'''nvironment.
 
:::::» ''More details'': '''[[MITOEAGLE]]'''


[[Gnaiger E |Erich]]
[[File:MITOEAGLE-MitoGlobal.jpg|px1200|link=MITOEAGLE|MiPArt Gallery: World health worries by Odra Noel (2012)]]
<br />
Bioblast Chief Editor
<br />
<br />
''[[MitoPedia]] - high-resolution terminology - matching measurements at high-resolution, in the spirit of [[Gentle Science]].''</big>


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<div style="float:right">[[Impressum]], [[Bioblast track]], [[Bioblast editorial board|Editorial board]]
<div style="float:right">[[Impressum]], [[Bioblast track]], [[Bioblast editorial board|Editorial board]]

Revision as of 12:48, 22 February 2017

Bioblasts - Richard Altmann and MiPArt by Odra Noel

Bioblast about         MitoPedia         MitoFit         Gentle Science         MitoGlobal         Impressum



Bioblast wiki

Bioblast - The mt-information synthase for MitoPedia, MitoFit, and more.

Bioblast Boost - in the spirit of Gentle Science: >600,000 times
Bioblast:About


Bioblast alert 2017(01): 2017-02-03


Gentle Science
» MitoGlobal first - science beyond borders
» Preprints for Gentle Science - Scientists take pride in their work and will be guided by their own internal standards in deciding when their work is ready to be released to the community. .. the paper can receive input from more than two or three referees, which could help authors correct flawed experiments/statements and help produce a better final product published in the journal. .. Journals then may be incentivized to look more toward quality than speed and seek to publish the definitive work that will stand the test of time .. - Quoted from Vale 2015.


MitoPedia
MitoPedia: SUIT - first steps towards a data bank of SUIT protocols
Updated terminology with SUIT protocols - open for discussion: Lemieux H, Blier PU, Gnaiger E (2017) Remodeling mitochondrial pathway control of oxidative phosphorylation by temperature in the heart. bioRxiv doi: https://doi.org/10.1101/103457.


COST Action MITOEAGLE


With best wishes and kind regards,
Erich
Bioblast Chief Editor




COST Action MITOEAGLE
COST Logo.jpg

COST Action CA15203 MITOEAGLE

The objective of the MITOEAGLE network is to improve our knowledge on mitochondrial function in health and disease related to Evolution, Age, Gender, Lifestyle and Environment.
» More details: MITOEAGLE

MiPArt Gallery: World health worries by Odra Noel (2012)


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