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Difference between revisions of "Bioblast"

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[[File:Bioblast wiki.jpg|940px|link=http://www.bioblast.at/index.php/Bioblast|Bioblasts - Richard Altmann and MiPArt by Odra Noel]]
[[File:Bioblast wiki.jpg|940px|link=http://www.bioblast.at/index.php/Bioblast|Bioblasts - Richard Altmann and MiPArt by Odra Noel]]
{{Bioblast navigation line}}
{{Bioblast navigation line}}
[[Image:BB-Bioblast-text.jpg|left|140px|link=http://www.bioblast.at/index.php/Bioblast|Bioblast wiki]]
[[Image:BB-Bioblast-text.jpg|left|140px|Bioblast wiki]]


<div style="font-size:15px;font-weight:bold;;color:#005199;padding:5px;border-bottom:1px solid #aaaaaa;text-align:left;margin:0px;">
<div style="font-size:15px;font-weight:bold;;color:#005199;padding:5px;border-bottom:1px solid #aaaaaa;text-align:left;margin:0px;">


<big><big><big><big><big>'''[[Bioblast]]'''</big></big></big></big></big>
<big><big><big><big><big>'''[[Bioblast]]'''</big></big></big></big></big> - The '''''mt-information synthase''''' for MitoPedia, MitoFit, and more.
 
:::::: '''Bioblast Boost''' - in the spirit of [http://www.bioblast.at/index.php/Gentle_Science Gentle Science]: '''>600,000 times'''
:::: The '''''mt-information synthase''''' for MitoPedia, MitoFit, and more
:::::: '''[[Bioblast:About]]'''
:::: '''Bioblast Boost''' - in the spirit of Gentle Science
</div>
</div>
 
<br />
****: [[MITOEAGLE |»MITOEAGLE today]]


{| class="wikitable" border="1"
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=== [[Bioblast alert]] 2016(01): 2016-02-10 ===
=== [[Bioblast alert]] 2017(01): 2017-02-03 ===
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[[Image:Gentle-Science_Ganesha.jpg|left|60px|link=http://www.bioblast.at/index.php/Gentle_Science|Gentle Science]]
:::: {{Template:MitoGlobal first}}


[[Image:MitoPedia.jpg|left|100px|link=http://www.bioblast.at/index.php/MitoPedia|MitoPedia]]  
::::» [[Gentle_Science#Preprints_for_Gentle_Science |'''Preprints for Gentle Science''']] - ''Scientists take pride in their work and will be guided by their own internal standards in deciding when their work is ready to be released to the community. .. the paper can receive input from more than two or three referees, which could help authors correct flawed experiments/statements and help produce a better final product published in the journal. .. Journals then may be incentivized to '''look more toward quality than speed''' and seek to publish the definitive work that will stand the test of time ..'' - Quoted from [[Vale 2015 Proc Natl Acad Sci U S A |Vale 2015]].
 
<big>Dear colleagues:
<br />
<br />
[[Image:MitoPedia.jpg|left|60px|link=http://www.bioblast.at/index.php/MitoPedia|MitoPedia]]
:::: '''[[MitoPedia: SUIT]] - first steps towards a data bank of SUIT protocols'''


Over the past years, there was a continuous struggle to find a language for translating our experimental findings obtained from [[SUIT protocols]] into useful information.  
:::: '''Updated terminology with SUIT protocols - open for discussion:''' [[Lemieux 2017 bioRxiv |Lemieux H, Blier PU, Gnaiger E (2017) Remodeling mitochondrial pathway control of oxidative phosphorylation by temperature in the heart. bioRxiv doi: https://doi.org/10.1101/103457]].
<br />
<br />
[[Image:MITOEAGLE-logo.jpg|left|60px|link=http://www.mitoglobal.org/index.php/MITOEAGLE|COST Action MITOEAGLE]]
::::* '''2017-Mar-21 to 23''' [http://www.bioblast.at/index.php/MITOEAGLE_Barcelona_2017 Barcelona ES: Mitochondrial mapping MC meeting and workshops COST Action MITOEAGLE]


Still our standard terminology and some even less consistent variations are not commonly understandable. Despite all efforts, including sequential editions of ‘MitoPathways’ ([[Gnaiger 2014 MitoPathways |The Blue Book]]), those attempts were basically a failure: We cannot expect any audience to grasp our message, if we say ‘Complex I’ – but actually have in mind the pathway from NADH-linked substrates to CI - CIII - CIV. Should we rather say CI-CIII-CIV-linked? (???)
<br />


Or even worse (my mistake!): We say ‘CI<small>&</small>II’ (and worse: ‘CI+II’: are the two enzymes added??), but we actually mean CI<small>&</small>II - CIII - CIV !!!
:::: With best wishes and kind regards,
<br />


I invite you to challenge fundamentally the way we think and talk and write about our results. To drop the CI-linked, CII-linked, CI<small>&</small>II (CI+II) terminology is not trivial but is a necessary step. At this stage, you and many colleagues will not like to make a real change. But such a change is not only important but necessary to make ourselves understood by a general audience, to make our field of mitochondrial physiology less confusing and more attractive. Perhaps we can even attain a deeper understanding among the involved specialists - the Bioblasts.
:::: [[Gnaiger E |Erich]]
:::: Bioblast Chief Editor
<br />
<br />
 
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If you agree that in mitochondrial respiratory physiology we should '''not say ‘Complex I’ for what IS NOT Complex I''', that we should not talk about a subset of '''enzyme complexes''' when we have in mind much more '''complicated pathways''' fuelled by a selection and combination of specific '''substrate types''', then I seriously ask you to stop for a moment and take a look at some new entries into MitoPedia which I have prepared during the past months.
<br />
<br />


:» Substrate types and pathway types: [[Substrate types]]
<br />
:» [[Categories of SUIT protocols]]
<br />
:» [[SUIT protocol names]]
<br />


I am looking forward to your feedback. Your input will be essential to find a common language for communication with the people whom we want to reach with our research in mitochondrial physiology. Lets cooperate in an effort on quality management of reporting our results. The messages of mitochondrial physiology need to be understood on a global scale, to support the various health systems in encouraging modern populations to become and stay [[MitoFit]].  
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<big><big>
[[File:MITOEAGLE-representation.jpg|right|250px|link=MITOEAGLE|COST Action MITOEAGLE]]
[[File:COST Logo.jpg|250px|link=MITOEAGLE|right]]
=== COST Action CA15203 MITOEAGLE ===
:::: The objective of the MITOEAGLE network is to improve our knowledge on mitochondrial function in health and disease related to '''E'''volution, '''A'''ge, '''G'''ender, '''L'''ifestyle and '''E'''nvironment.


With best wishes and kind regards,
:::::» ''More details'': '''[[MITOEAGLE]]'''
<br />


[[Gnaiger E |Erich]]
[[File:MITOEAGLE-MitoGlobal.jpg|px1200|link=MITOEAGLE|MiPArt Gallery: World health worries by Odra Noel (2012)]]
<br />
Bioblast Chief Editor
<br />
<br />
''[[MitoPedia]] - high-resolution terminology - matching measurements at high-resolution, in the spirit of [[Gentle Science]].''</big>


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<div style="float:right">[[Impressum]], [[Bioblast track]], [[Bioblast editorial board|Editorial board]]
<div style="float:right">[[Impressum]], [[Bioblast track]], [[Bioblast editorial board|Editorial board]]

Revision as of 11:48, 22 February 2017

Bioblasts - Richard Altmann and MiPArt by Odra Noel

Bioblast about         MitoPedia         MitoFit         Gentle Science         MitoGlobal         Impressum



Bioblast wiki

Bioblast - The mt-information synthase for MitoPedia, MitoFit, and more.

Bioblast Boost - in the spirit of Gentle Science: >600,000 times
Bioblast:About


Bioblast alert 2017(01): 2017-02-03


Gentle Science
» MitoGlobal first - science beyond borders
» Preprints for Gentle Science - Scientists take pride in their work and will be guided by their own internal standards in deciding when their work is ready to be released to the community. .. the paper can receive input from more than two or three referees, which could help authors correct flawed experiments/statements and help produce a better final product published in the journal. .. Journals then may be incentivized to look more toward quality than speed and seek to publish the definitive work that will stand the test of time .. - Quoted from Vale 2015.


MitoPedia
MitoPedia: SUIT - first steps towards a data bank of SUIT protocols
Updated terminology with SUIT protocols - open for discussion: Lemieux H, Blier PU, Gnaiger E (2017) Remodeling mitochondrial pathway control of oxidative phosphorylation by temperature in the heart. bioRxiv doi: https://doi.org/10.1101/103457.


COST Action MITOEAGLE


With best wishes and kind regards,
Erich
Bioblast Chief Editor




COST Action MITOEAGLE
COST Logo.jpg

COST Action CA15203 MITOEAGLE

The objective of the MITOEAGLE network is to improve our knowledge on mitochondrial function in health and disease related to Evolution, Age, Gender, Lifestyle and Environment.
» More details: MITOEAGLE

MiPArt Gallery: World health worries by Odra Noel (2012)


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