MitoPedia: Preprints

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MitoPedia: Preprints

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MitoPedia: Preprints

ASAPbioScience only progresses as quickly and efficiently as it is shared. But even with all of the technological capabilities available today, the process of publishing scientific work is taking longer than ever. ASAPbio (Accelerating Science and Publication in biology) is a scientist-driven nonprofit working to address this problem by promoting innovation and transparency in life sciences communication. In 2015, ASAPbio founder Ron Vale published an analysis of the increasing time to first-author publication among graduate students at UCSF, and proposed a more widespread use of preprints in the life sciences as a potential solution.
Advantage of preprintsThe advantages of preprints, the excitement and concerns about the role that preprints can play in disseminating research findings in the life sciences are discussed by N Bhalla (2016).
ArXiv preprint serverarXivarXiv is a classic preprint server initiated in 1991 by Paul Ginsparg. {Quote: is a highly-automated electronic archive and distribution server for research articles. Covered areas include physics, mathematics, computer science, nonlinear sciences, quantitative biology, quantitative finance, statistics, electrical engineering and systems science, and economics. arXiv is maintained and operated by Cornell University with guidance from the arXiv Scientific Advisory Board and the arXiv Member Advisory Board, and with the help of numerous subject moderators. ~ end of Quote}. arXiv rejects abstracts that are submitted without accompanying paper.
BioRxiv preprint server for biologybioRxivbioRxiv (pronounced "bio-archive") is a free online archive and distribution service for unpublished preprints in the life sciences. It was launched in 2013 by Cold Spring Harbor Laboratory Press in New York, and is operated by Cold Spring Harbor Laboratory, a not-for-profit research and educational institution. By posting preprints on bioRxiv, authors are able to make their findings immediately available to the scientific community and receive feedback on draft manuscripts before they are submitted to journals. bioRxiv is intended for rapid sharing of new research. Some review articles contain new data/analyses and may therefore be deemed appropriate. Reviews that solely summarize existing knowledge are not appropriate and neither are term papers, book excerpts, and undergraduate dissertations.
Copyright{Quote} All preprints are posted with a Creative Commons CC BY 4.0 license, ensuring that authors retain copyright and receive credit for their work, while allowing anyone to read and reuse their work. {end of Quote}
Creative Commons Attribution LicenseOpen Access preprints (not peer-reviewed) are distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited. © remains with the authors, who have granted MitoFit an Open Access preprint licence in perpetuity.
Digital Object IdentifierDOIA Digital Object Identifier, DOI, is a persistent identifier used to uniquely identify online publications in order to ensure they remain traceable, searchable and citable over the long term. Compared to other types of persistent identifiers, the DOI system is widespread and well established in the life sciences arena, and it provides widely accepted visible proof that a publication is citable.
Extended abstractsIn the context of MiPevents and MitoEAGLE events, extended abstracts are accepted for preprint publication in MitoFit Preprint Archives upon evaluation by MitoEAGLE MC members. Publishing extended abstracts with MitoFit Preprint Archives does not preclude later full journal publication, but will make your work fully citable, by assigning each manuscript a unique DOI number, and facilitate discovery and feedback.
F1000ResearchF1000Research is an Open Research publishing platform for life scientists, offering immediate publication of articles and other research outputs without editorial bias. All articles benefit from transparent peer review and the inclusion of all source data. It is thus not a preprint server, but posters and slides can be published without author fees. Published posters and slides receive a DOI (digital object identifier) and become citable after a very basic check by our in-house editors.
Journal publicationIn most cases journal publication {Quote} will not be affected by posting a preprint. However, there are some publishers that do not consider papers that have already appeared online. We strongly recommend that you check all journals that you might submit to in advance {end of Quote}. A list of academic journals by preprint policy is available.
MitoFit DOI Data CenterMitoFit DOI DCThe MitoFit DOI Data Center is responsible for the provision of digital identifiers, for the storage and ensuring the persistence of the scientific objects, the provision of access, review process and maintenance of the Metadata, and quality control.
MitoFit Preprint ArchivesMitoFit Preprint ArchMitoFit Preprint Archives is an Open Access preprint server for mitochondrial physiology and bioenergetics.
OSF Preprint serverLeading preprint service providers use OSF Preprints as an open source infrastructure to support their communities. You should upload your preprint to whichever preprint server best fits your topic and the community that you would like to reach. If there isn’t a community-driven preprint server for your discipline, OSF Preprints is available for any discipline. Currently, you can only share your preprint on one community preprint server. It’s on our roadmap to allow users to submit a preprint to multiple community preprint servers. However, to improve discoverability across communities, all preprints shared on OSF Preprints and community preprint servers are indexed and searchable via Right now, it is not possible to add subjects. However, you can add tags with additional subject areas or keywords to improve discoverability. COS supports communities operating their own branded community preprint services using OSF Preprints as the backend.OSF is based in Charlottesville, VA, USA.
Open AccessOALeft Open Access (OA) academic articles comprise all different forms of published research that are distributed online, free of charge and with an open license to facilitate the distribution and reuse. The open access repositories serve as the perfect vehicle to transmit free knowledge, including but not limited to peer-reviewed and non-peer-reviewed academic journal articles, conference papers, theses, book chapters and monographs. The open access movement was driven by the problems of social inequality caused by restricting access to academic research, trying to promote more democratic access to scientific knowledge, as well as addressing the economic challenges and unsustainability of academic publishing.
PREreviewPREreview encourages scientists to post their scientific outputs as preprints. PREreview makes it easier to start and run a Preprint Journal Club, or integrate preprint review into conventional journal clubs. PREreview seeks to diversify peer review in the academic community by crowdsourcing pre-publication feedback to improve the quality of published scientific output, and to train early-career researchers (ECRs) in how to review others' scientific work. We want to facilitate a cultural shift in which every scientist posts, reads, and engages with preprints as standard practice in scholarly publishing. We see PREreview as a hub to support and nurture the growth of a community that openly exchanges timely, constructive feedback on emerging scientific outputs. We believe that by empowering ECRs through peer review training programs, thereby increasing the diversity of researchers involved in the peer review process, PREreview will help establish a healthier and more sustainable culture around research dissemination and evaluation. This project was born in April 2017 as a collaboration between Samantha Hindle and Daniela Saderi, scientists and ASAPbio Ambassadors, with help from Josh Nicholson, at the time working for Authorea.
PeerJ Preprints 'pre-print' area of PeerJPeerJ Preprints is the 'pre-print' area of the Open Access journal PeerJ. Similar to preprint servers that already exist (for example, authors can submit draft, incomplete, or final versions of articles they are working on. By using this service, authors establish precedent; they can solicit feedback; and they can work on revisions of their manuscript. Once they are ready, they can submit their preprint article into PeerJ (although it is not a requirement to do so).

PeerJ Preprints was launched in April 2013. It only accepts submissions in the same subject areas as PeerJ (biological, medical and environmental sciences) and PeerJ Computer Science. In order to submit to PeerJ Preprints, at least the submitting author must have a user account with PeerJ. There is no pre-publication peer-review of submissions; however we do perform basic checks to ensure conformity with our policies. Submissions are made using the same platform as with the peer-reviewed journals, although some of the requirements are less stringent. Articles are not typeset, but we do provide automated conversion into PDF. The default is for a PeerJ Preprints publication to be fully open to all viewers (what we call a 'public' pre-print).

PeerJ is an Open Access, peer-reviewed, scholarly journal. It considers and publishes research articles in the biological, medical and environmental sciences. It aims for rapid decision making and will publish articles as soon as they are ready. PeerJ is based in both San Diego, US, and London, UK.
PrePubMedPrePubMed indexes preprints from arXiv q-bio, PeerJ Preprints, bioRxiv, F1000Research,, The Winnower, Nature Precedings, and Wellcome Open Research. Articles are not stored on PrePubMed, but you will be linked to the article at the respective site.
PreprintA preprint is {Quote} a way in which a manuscript containing scientific results can be rapidly communicated from one scientist, or a group of scientists, to the entire scientific community {end of Quote}.
Preprints multidisciplinary preprint platformPreprints is a platform dedicated to making early versions of research outputs permanently available and citable. We post original research articles and comprehensive reviews, and papers can be updated by authors at any time. Content on Preprints is not peer-reviewed and can receive feedback from readers. Preprints focuses on original research articles and comprehensive reviews. Editorials, discussion papers, and commentary are usually not suitable. Preprints is fully owned and funded by MDPI, an open access journal publisher. It is run on a non-profit basis. You do not need to submit to an MDPI journal in order to post a preprint here, any work is welcome. If you do submit to an MDPI journal, you will be invited to submit to during the submission process.

Preprints has the following features: Multidisciplinary: We cover all research disciplines. Open access: All preprints are posted with a Creative Commons CC BY 4.0 license, ensuring that authors retain copyright and receive credit for their work, while allowing anyone to read and reuse their work. Citation via Crossref DOI: Each preprint has a unique digital object identifier issued by Crossref. This makes them instantly citable and provides a permanent link to the article, even if the URL on our platform changes. New versions of preprints receive a different DOI. Comment on any article: Authors can receive public or private feedback from readers directly from the preprint abstract page. Simple submission process: Submitting a preprint only requires basic information, our team of editors will do the rest and post your preprint as soon as possible. is a platform for peer-reviewed, scientific open-access journals operated by MDPI, based in Basel, Switzerland (since 1996). MDPI is a member of the Committee on Publication Ethics (COPE). To verify the originality of content submitted to our journals, we use iThenticate to check submissions against previous publications. MDPI works with Publons to provide reviewers with credit for their work.
Scope of mtFPAThe areas covered in MitoFit Preprint Archives (mtFPA) include mitochondrial physiology, bioenergetics and ergodynamics. For more details, see Submission form for MitoFit Preprint Arch.
Submission form for MitoFit Preprint ArchManuscripts submitted to MitoFit Preprint Archives have to be accompanied by this submission form.


References: Preprints

 Was published in yearHas title
Learn 2019 Nature2019Learn JR (2019) What bioRxiv’s first 30,000 preprints reveal about biologists. Nature NEWS 22 January 2019.
Tennant 2019 MetaArXiv Preprints2019Tennant J, Bauin S, James S, Kant J (2019) The evolving preprint landscape: introductory report for the Knowledge Exchange working group on preprints.
Sarabipour 2019 PLoS Biol2019Sarabipour S, Debat HJ, Emmott E, Burgess SJ, Schwessinger B, Hensel Z (2019) On the value of preprints: An early career researcher perspective. PLoS Biol 17(2):e3000151.
Abdill 2019 bioRxiv2019Abdill RJ, Blekhman R (2019) Tracking the popularity and outcomes of all bioRxiv preprints. bioRxiv
Gnaiger 2019 MitoFit Preprint Arch Editorial2019Gnaiger E (2019) Editorial: A vision on preprints for mitochondrial physiology and bioenergetics. MitoFit Preprint Arch doi:10.26124/mitofit:190002.v2.
Avasthi 2018 eLife2018Avasthi P, Soragni A, Bembenek JN (2018) Point of View: Journal clubs in the time of preprints. eLife 7:e38532.
Maggio 2018 Perspect Med Educ2018Maggio LA, Artino AR Jr, Driessen EW (2018) Preprints: facilitating early discovery, access, and feedback. Perspect Med Educ 7:287-9.
Tennant 2018 Nature2018Tennant J, Gatto L, Logan C (2018) Preprints help journalism, not hinder it. Nature 560:553.
Sarabipour 2018 Nature2018Sarabipour S (2018) Preprints are good for science and good for the public. Nature 560:553.
Abbasi 2018 J R Soc Med2018Abbasi K (2018) A giant step for science: JRSM welcomes preprints in medical science. J R Soc Med 111:263.
Serghiou 2018 JAMA2018Serghiou S, Ioannidis JPA (2018) Altmetric scores, citations, and publication of studies posted as preprints. JAMA 319:402-4.
Fraser 2018 Nature2018Fraser J, Polka J (2018) Together scientists and journalists can spot poor preprints. Nature 560:553.
Sheldon 2018 Nature2018Sheldon T (2018) Preprints could promote confusion and distortion. Nature 559:445.
Da Silva 2018 Med J Armed Forces India2018da Silva JAT (2018) The preprint debate: What are the issues?. Med J Armed Forces India 74:162-64.
Oakden-Rayner 2018 Int J Epidemiol2018Oakden-Rayner L, Beam AL, Palmer LJ (2018) Medical journals should embrace preprints to address the reproducibility crisis. Int J Epidemiol 47:1363-5.
Kleinert 2018 Lancet2018Kleinert S, Horton R; Editors of the Lancet family of journals (2018) Preprints with The Lancet: joining online research discussion platforms. Lancet 391:2482-3.
Gross 2018 Neurology2018Gross RA (2018) Preprints and the implications for subsequent peer review and publishing. Neurology 91:855-6.
Klein 2018 Int J Digit Libr2018Klein M, Broadwell P, Farb SE, Grappone T (2018) Comparing published scientific journal articles to their pre-print versions. Int J Digit Libr
Bove-Fenderson 2018 JBMR Plus2018Bove-Fenderson E, Duffy K, Mannstadt M (2018) Broadening our horizons: JBMR and JBMR Plus embrace preprints. JBMR Plus 2:59-61.
Committee 2018 COPE Discussion Document2018Committee on Publication Ethics (2018) Discussion document on preprints. COPE Discussion Document
Neylon 2017 F1000Research2017Neylon C, Pattinson D, Bilder G, Lin J (2017) On the origin of nonequivalent states: How we can talk about preprints [version 1; referees: 2 approved]. F1000Research 6:608
Verma 2017 Proc Natl Acad Sci U S A2017Verma IM (2017) Preprint servers facilitate scientific discourse. Proc Natl Acad Sci U S A 114:12630.
Packer 2017 SciELO2017Packer AL, Santos S, Meneghini R (2017) SciELO preprints on the way. SciELO
Kaiser 2017 Science2017Kaiser J (2017) In a 'forgotten experiment,' biologists almost launched the preprint revolution—5 decades ago. Science doi:10.1126/science.aap7593.
Ginsparg 2017 arXiv2017Ginsparg P (2017) Preprint Déjà Vu: an FAQ. arXiv:1706.04188.
Cobb 2017 PeerJ Preprints2017Cobb M (2017) The prehistory of biology preprints: a forgotten experiment from the 1960s. PeerJ Preprints 5:e3174v1
Chawla 2017 Nature2017Chawla DS (2017) When a preprint becomes the final paper. Nature Doi:10.1038/nature.2017.21333.
Hindle 2017 eLife2017Hindle A, Saderi D (2017) PREreview — a new resource for the collaborative review of preprints. eLife Labs Oct 25, 2017.
Bourne 2017 PLoS Comput Biol2017Bourne PE, Polka JK, Vale RD, Kiley R (2017) Ten simple rules to consider regarding preprint submission. PLoS Comput Biol 13:e1005473.
Kaiser 2017 Science 3572017Kaiser J (2017) The preprint dilemma. Science 357:1344-9.
Berg 2017 Science2017Berg J (2017) Preprint ecosystems. Science 357:1331.
Iwema 2016 F1000Research2016Iwema CL, LaDue J, Zack A, Chattopadhyay A (2016) search.bioPreprint: a discovery tool for cutting edge, preprint biomedical research articles. F1000Research 5:1396 [version 2; referees: 2 approved].
Chalmers 2016 F1000Research2016Chalmers I, Glasziou P (2016) Should there be greater use of preprint servers for publishing reports of biomedical science?. F1000Research 5:272 [version 1; referees: not peer reviewed].
Berg 2016 Science2016Berg JM, Bhalla N, Bourne PE, Chalfie M, Drubin DG, Fraser JS, Greider CW, Hendricks M, Jones C, Kiley R, King S, Kirschner MW, Krumholz HM, Lehmann R, Leptin M, Pulverer B, Rosenzweig B, Spiro JE, Stebbins M, Strasser C, Swaminathan S, Turner P, Vale RD, VijayRaghavan K, Wolberger C (2016) Preprints for the life sciences. Science 352:899-901.
Bhalla 2016 Mol Biol Cell2016Bhalla N (2016) Has the time come for preprints in biology? Mol Biol Cell 27:1185-7.
Citron 2015 Proc Natl Acad Sci U S A2015Citron DT, Ginsparg P (2015) Patterns of text reuse in a scientific corpus. Proc Natl Acad Sci U S A 112:25-30.
Vale 2015 Proc Natl Acad Sci U S A2015Vale RD (2015) Accelerating scientific publication in biology. Proc Natl Acad Sci U S A 112:13439-46.
Callaway 2013 Nature2013Callaway E (2013) Preprints come to life. Nature 503:180.
Desjardins-Proulx 2013 PLOS Biol2013Desjardins-Proulx P, White EP, Adamson JJ, Ram K, Poisot T, Gravel D (2013) The case for open preprints in biology. PLoS Biol 11:e1001563. doi: 10.1371/journal.pbio.1001563.
Jackson 2002 Notices Amer Mathemat Soc2002Jackson A (2002) From preprints to e-prints: the rise of electronic preprint servers in mathematics. Notices Amer Mathemat Soc 49:23–32.
Hatch 1998 JAMA1998Hatch CL, Goodman SN (1998) Perceived value of providing peer reviewers with abstracts and preprints of related published and unpublished papers. JAMA 280:273-4.

Preprints for Gentle Science

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