Cardiolipin

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Cardiolipin

Description

Cardiolipin, CL, is a double phospholipid (having 4 fatty acyl chains) in the mitochondrial inner membrane (mtIM) which plays an important role in mitochondrial bioenergetics. CL is involved in the mitochondria-dependent pathway of apoptosis, participates in the function and stabilization of mitochondrial respiratory complexes and supercomplexes and also contributes to mitochondrial integrity.

Contributed by Sparagna G 2016-04-18

Abbreviation: CL

Reference: Paradies 2014 Biochim Biophys Acta, Chicco 2007 Am J Physiol Cell Physiol